Sugar acids and derivatives
Medchemexpress LLC Semaglutide-FITC (semaglutide-Lys(FITC)) | 4502.96 | 25 MG
Semaglutide-FITC is a FITC-labeled semaglutide, a GLP-1R agonist. It is used to directly track the distribution, cellular uptake, and transmembrane transport processes of vesicles. It can also be employed to study the movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
- FITC-labeled semaglutide (a GLP-1R agonist).
- Directly track the distribution, cellular uptake, and transmembrane transport process of vesicles via fluorescence imaging and flow cytometry.
- Study movement and penetration ability of mixed vesicles in porcine intestinal mucus in vitro.
Medchemexpress LLC Beta-asarone (Standard) | 5273-86-9 | 208.25 | 25 MG
Beta-asarone (Standard) | 5273-86-9 | 208.25 | 25 MG
![eMolecules cis-Bicyclo[3.1.0]hexan-3-ol | 694-43-9 | MFCD20921684 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502193492.JPG-250.jpg)
eMolecules cis-Bicyclo[3.1.0]hexan-3-ol | 694-43-9 | MFCD20921684 | 1g
Combi-Blocks | cis-Bicyclo[3.1.0]hexan-3-ol | 1g | 267210850 | ST-7476 | 97.000 | 694-43-9 | MFCD20921684 | 98.145 | C6H10O
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eMolecules Building Block Tool
Medchemexpress LLC Msx-127 (NSC-23026) | 6616-56-4 | MFCD00087356 | 99.7% | 308.37 g/mol | C16H24N2O4 | 25 MG
MSX-127 is a small-molecule C-X-C chemokine receptor 4 (CXCR4) antagonist supplied for research use. It inhibits CXCR4-mediated signaling and has been used in studies of cancer metastasis. The compound is provided as a high-purity solid with documented storage and solubility properties suitable for in vitro research applications.
- Acts as a CXCR4 antagonist relevant to cancer and immunology research.
- High reported purity (≈99.68%).
- Molecular weight 308.37 g/mol and formula C16H24N2O4.
- White to off-white solid appearance.
- Soluble in DMSO (≈41.67 mg/mL); ultrasonic assistance may be required.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
AdipoGen N-Z-L-Homoserine lactone
Chemical. CAS 35677-89-5. Formula C12H13NO4. MW 235.24. N-Z-L-Homoserine lactone is a synthetic building block or intermediate used in the synthesis of biological active agents and analogs of bacterial quorum-sensing signaling molecules. N-Z-L-Homoserine lactone is shown to irreversibly inactivate the 3C cysteine proteinase of hepatitis A virus HAV and might be a scaffold for potent cyteine protein inhibtiors. Shown to reduce the lag phase duration LPD and increase the exponential growth rate EGR of three strains of Pseudomonas fluorescens isolated from refrigerated raw milk.
Medchemexpress LLC Integrin alpha 5 bet 5ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa
Medchemexpress LLC Integrin alpha 8 bet 50ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-10 His C-Flag labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 Flag His) has molecular weight of 85-140 kDa
Medchemexpress LLC Integrin alpha X bet 5ug
Integrin -X/ -2 is a receptor for fibrinogen that recognizes GPR sequences It plays a key role in inflammatory responses particularly in monocyte adhesion and chemotaxis Integrin alpha X beta 2 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein expressed by HEK293 with C-His labeled tag Integrin alpha X beta 2 Protein Human (HEK293 His) has molecular weight of 130-150 kDa (ITGAX) 85-96 kDa (ITGB2) respectively
Apexbio Technology LLC β-Interleukin II (44-56) 25mg
beta-Interleukin II 44-56 is a synthetic peptide fragment derived from interleukin-2 (IL-2) It is designed to serve as a functional IL-2 derivative peptide thereby facilitating studies on immune system modulation and T-cell regulation beta-Interleukin II 44-56 exerts its biological activity by providing a representative segment of IL-2 which supports investigation of T-cell activity regulatory T-cell mechanisms and immunological signaling pathways in cellular and molecular immunology research Based on these pharmacological properties beta-Interleukin II 44-56 holds research potential in studies of immune regulation T-cell biology and immune-related disease mechanisms
Medchemexpress LLC Mosapride citrate dihydrate | 636582-62-2 | 99.6% | 25 MG
Mosapride citrate dihydrate is a gastroprokinetic agent that acts as a 5-hydroxytryptamine4 receptor agonist. It has been extensively used in research related to various gastrointestinal disorders. This compound also potently inhibits Kv4.3 in a concentration-dependent manner, with an IC50 value of 15.2 μM. In vivo, it specifically stimulates upper gastrointestinal motility.
- Acts as a 5-hydroxytryptamine4 receptor agonist
- Used in research for gastrointestinal disorders
- Potently inhibits Kv4.3
- Selectively stimulates upper gastrointestinal motility in vivo
AdipoGen 3-Oxo-C9-L-HSL
Chemical. CAS 441350-70-5. Formula C13H21NO4. MW 255.31. N-3-Oxononanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
BIOHIPPO T-bet-TAR-BSD LV
T-bet-TAR-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC PROTAC BET-binding moiety 1 | 2093387-77-8 | 80.4% | 487.51 | C25H25N7O4 | 1 ML
PROTAC BET-binding moiety 1 is a small-molecule intermediate used in the synthesis of high-affinity BET (bromodomain and extra-terminal) inhibitors. Supplied as a ready-to-use DMSO solution (10 mM, 1 mL), it is intended for medicinal chemistry and PROTAC development targeting BRD2, BRD3, BRD4, and BRDT.
- Ready-to-use 10 mM solution in DMSO.
- Suitable for synthesis of BET inhibitors and PROTACs.
- Molecular formula C25H25N7O4 and molecular weight 487.51.
- Reported purity 80.4%.
- CAS number 2093387-77-8 for unambiguous identification.