Sugar acids and derivatives
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 10MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor provided as a high-purity research reagent for epigenetic and oncology studies. It is supplied as a powder in multiple pack sizes and displays cellular activity against AML MV4-11 cells, supporting biochemical and cell-based assays. Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- High purity (99.74%).
- Molecular formula C19H19N5O; molecular weight 333.39.
- Demonstrated inhibition of hIL-6 transcription and c-myc activity (IC50 ≤ 0.3 μM).
- Available in multiple pack sizes for flexible experimental design.
- Supplied as a powder with defined cold-storage stability.
Medchemexpress LLC Methanone, (5-methoxy-1H-indol-2-yl)phenyl- | 74588-78-6 | C16H13NO2 | 25 MG
D-64131 is an orally active tubulin inhibitor, exhibiting antimitotic activity and primarily used for cancer research. It effectively inhibits tubulin polymerization with an IC50 of 0.53 μM.
- Binds to β-tubulin, destabilizing microtubules and arresting mitotic cells in M-phase
- Inhibits proliferation of tumor cells from various organs and tissues
- Cytotoxic toward MDR/MRP tumor cell lines
- Suppresses U373 proliferation and cell cycle
- Significantly inhibits tumor growth in human amelanoic melanoma xenograft models in vivo
- Exhibits oral bioavailability and is well tolerated at efficacious doses
Medchemexpress LLC Integrin alpha 2 beta 1 protein | >95.0% | 100UG
Recombinant human integrin alpha 2 beta 1 heterodimer expressed in HEK293 cells. Supplied as a lyophilized, C-terminal His-tagged protein formulated in PBS with trehalose, it is intended for biochemical and cell-based assays and is characterized by purity and low endotoxin as reported on the certificate of analysis.
- High purity (≥95.0%) confirmed by reducing SDS-PAGE.
- Molecular weight consistent with heterodimer (110-140 kDa).
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Lyophilized formulation in PBS with 8% trehalose for enhanced stability.
- C-terminal His tag enables affinity capture or detection.
- Recommended reconstitution concentration not less than 100 μg/mL in ddH2O.
- Store at -20°C; aliquot and store at -80°C for long-term stability.
Medchemexpress LLC Integrin alpha V bet 50ug | 50ug
Integrin alpha V beta 3 (ITGAV ITGB3) functions as a receptor for CD40LG enhancing Lilrb4a inhibitory effects on mast cell activation It suppresses marginal zone B cell antibody production through Lilrb4a interaction ITGAV ITGB3 forming a heterodimer with ITGAV interacts with ligands such as RAB25 CIB1 FBLN5 and more It also forms a complex with PTPRZ1 and PTN stimulating endothelial cell migration Integrin alpha V beta 6 Protein Mouse (HEK293 His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Mouse (HEK293 His) has molecular weight of 90-140 kDa
Medchemexpress LLC N-acetylneuraminic acid-13C-3 | 131-48-6 | MFCD00006620 | 99.0% | 310.26 | C10H19NO9 (13C labeled) | 10 MG
N-Acetylneuraminic acid-13C-3 is a stable isotope-labeled form of N-acetylneuraminic acid used as an internal standard, tracer, or reference material in analytical chemistry and metabolomics for accurate quantification and metabolic tracing.
- 13C isotopic labeling at the 3-position for tracer studies.
- High purity, 99.0%.
- Suitable as an internal standard for LC-MS/MS quantification.
- Available in small mass quantities for analytical applications.
- Recommended storage: powder at -20°C for long-term, 4°C for short-term.
STA PHARMACEUTICAL US LLC 1-(Fmoc-aminomethyl)-beta-D-galacturonic acid | 5 g | CAS 655246-28-9 | MDL MFCD11974983
1-(Fmoc-aminomethyl)-beta-D-galacturonic acid is a Amino Acid reagent (Subcategory: Sugar AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 655246-28-9
- MDL: MFCD11974983
- InChIKey: USLKEBRNVKYNDJ-OMZCGLGVSA-N
- Molecular Weight: 429.425
- Molecular Formula: C22H23NO8
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29329900
- Country Of Origin: China
- IUPAC: (2S,3R,4R,5R,6S)-6-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
- SMILES: O=C([C@H]1O[C@@H](CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)[C@H](O)[C@@H](O)[C@H]1O)O
Medchemexpress LLC PAMP-12(human, porcine) | 196305-05-2 | 97.3% | 1618.93 | 5 MG
PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, processed from the adrenomedullin precursor. It is a potent hypotensive peptide that plays a role in cardiovascular control. This peptide is specifically PAMP[9-20] with a C-terminal amide structure and has demonstrated significant dose-dependent hypotensive effects in anesthetized rats.
- Potent hypotensive peptide
- Processed from adrenomedullin precursor
- Plays a role in cardiovascular control
- PAMP[9-20] with C-terminal amide structure
- For research use only
![Alkali Scientific MUG [4 Methylumbelliferyl β D glucuronide Trihydrate], 100 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660039.jpg-250.jpg)
Alkali Scientific MUG [4 Methylumbelliferyl β D glucuronide Trihydrate], 100 Mg
Methylumbelliferyl β-D Glucuronide Trihydrate, 100 mg is a highly sensitive biochemical reagent used for detecting glucuronidase activity in various biological samples. When cleaved by glucuronidases, this substrate releases a fluorescent product, making it ideal for enzyme assays and biochemical analysis. It is used in clinical diagnostics, genetic research, and microbiological analysis to detect glucuronidase activity. The high sensitivity and purity of this reagent allow for accurate and reproducible results in assays that require low detection limits, such as studies of metabolic disorders and microbial enzyme activity.