Sugar acids and derivatives
Medchemexpress LLC 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside | 37067-30-4 | 99.95% | 379.36 | 1 ML
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase. The enzyme functionality is assessed by its ability to remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from this compound. This product is supplied as a 10 mM solution in 1 mL of DMSO, ready for reconstitution. For optimal stability, the solution should be stored at 4°C, protected from light. Once in solvent, store at -80°C for up to 6 months or -20°C for 1 month, also protected from light.
- Fluorogenic substrate for N-acetyl-β-D-glucosaminidase
- Assesses enzyme functionality by removing terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues
- Can be prepared in DMSO at 50 mg/mL (131.80 mM)
- Requires ultrasonication for preparation
- Newly opened DMSO is recommended due to hygroscopic nature affecting solubility
![Medchemexpress LLC (S,E)-N-(4-(2-((6-(2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f]triazolo[4,3-a]diazepin-6-yl)acetamido)hexyl)amino)-2-oxoethoxy)benzyl)-2-cyano-3-(naphthalen-2-yl)acrylamide | 98.1% | 867.46 | C48H47ClN8O4S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288277.png-250.jpg)
Medchemexpress LLC (S,E)-N-(4-(2-((6-(2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f]triazolo[4,3-a]diazepin-6-yl)acetamido)hexyl)amino)-2-oxoethoxy)benzyl)-2-cyano-3-(naphthalen-2-yl)acrylamide | 98.1% | 867.46 | C48H47ClN8O4S | 10 MG
PROTAC BET Degrader-12 is a proteolysis targeting chimera (PROTAC) designed to selectively degrade bromodomain and extra-terminal (BET) family proteins such as BRD3 and BRD4. Supplied as a research reagent in small-mass packs, it is intended for use in targeted protein degradation and epigenetics studies.
- Selective BET protein degrader targeting BRD3 and BRD4.
- Purity 98.1% by HPLC.
- Molecular formula C48H47ClN8O4S; molecular weight 867.46.
- Available in small-mass packs (e.g., 10 mg) for research use.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or diagnostic use.
AdipoGen 3-oxo-C11-L-HSL
Chemical. CAS 216596-70-2. Formula C15H25NO4. MW 283.4. Synthetic. N-3-Oxoundecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Numerous species of bacteria employ 3OC11-HSL in cell-to-cell communication. Shown to have immune suppressive activity, inhibiting murine and human leucocyte proliferation.
![eMolecules 21085-72-3 | Acetobromo-?-D-glucuronic acid methyl ester, 98% | ChemScene | MFCD00061613 | 397.174 | C13H17BrO9 | 98.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 15g | 894453228](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000482129.jpg-250.jpg)
eMolecules 21085-72-3 | Acetobromo-?-D-glucuronic acid methyl ester, 98% | ChemScene | MFCD00061613 | 397.174 | C13H17BrO9 | 98.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 15g | 894453228
Acetobromo-?-D-glucuronic acid methyl ester, 98% | ChemScene | 21085-72-3 | MFCD00061613 | 397.174 | C13H17BrO9 | 98.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 15g | 894453228
Medchemexpress LLC D-Glucuronic acid sodium salt monohydrate | 207300-70-7 | 5 G
D-Glucuronic acid sodium salt monohydrate is a primary constituent of various anti-inflammatory proteoglycans. It has the ability to promote embryonic development and inhibit cell aggregation. Upon metabolization into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), which can lead to pain. Both D-Glucuronic acid sodium salt monohydrate and its derivative, glucurono-lactone, can serve as liver detoxifiers for human health prevention, and its derivatives also demonstrate anti-tumor activity. The product has a purity of 98.0% and is intended for research use only.
- Promotes embryonic development and inhibits cell aggregation
- Activates Toll-like receptor 4 (TLR4)
- Functions as a liver detoxifier
- Demonstrates anti-tumor activity (derivatives)
- Intended for research use only
- High purity
STA PHARMACEUTICAL US LLC 1-(Fmoc-aminomethyl)-beta-D-galacturonic acid | 50 g | CAS 655246-28-9 | MDL MFCD11974983
1-(Fmoc-aminomethyl)-beta-D-galacturonic acid is a Amino Acid reagent (Subcategory: Sugar AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 655246-28-9
- MDL: MFCD11974983
- InChIKey: USLKEBRNVKYNDJ-OMZCGLGVSA-N
- Molecular Weight: 429.425
- Molecular Formula: C22H23NO8
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29329900
- Country Of Origin: China
- IUPAC: (2S,3R,4R,5R,6S)-6-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
- SMILES: O=C([C@H]1O[C@@H](CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)[C@H](O)[C@@H](O)[C@H]1O)O
Medchemexpress LLC Beta-D-glucopyranosyl nitromethane | 81846-60-8 | 99.5% | C7H13NO7 | 25 MG
Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane, presented as a salt of a strongly basic anion exchanger in the OH cycle. This chemical is intended for research use only, serving as a laboratory chemical and for the manufacture of substances.
- Glycosyl derivative of nitromethane.
- Presented as a salt of a strongly basic anion exchanger in the OH cycle.
- Suitable for laboratory chemical applications.
- Used in the manufacture of substances.
Medchemexpress LLC Thymine 1-β-D-arabinofuranoside | 605-23-2 | 98.0% | 258.23 | 25 MG
Thymine 1-β-D-arabinofuranoside is a purine nucleoside analogue. Purine nucleoside analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis.
- Purine nucleoside analogue
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Solid appearance
- Off-white to light yellow color
- Melting/freezing point: 246-247°C
- Recommended storage: 4°C, stored under nitrogen
Medchemexpress LLC UDP-glucuronic acid trisodium | 63700-19-6 | 250 MG
UDP-glucuronic acid trisodium is a vital precursor for essential glycoconjugates found across various biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. Intended for research use only, this white to off-white solid has a high purity of 99.87%, a molecular weight of 646.23, and a chemical formula of C15H19N2Na3O18P2.
- Critical precursor for glycoconjugates
- High purity of 99.87%
- Promotes migration of liver cancer cells (Huh7, SK-Hep1, SNU449) by inducing EMT process in vitro
- Decreases E-cadherin levels and increases vimentin levels in Huh7 and SNU449 cells at 0.5 mM in vitro
![eMolecules 21085-72-3 | Acetobromo-alpha-D-glucuronic acid methyl ester | Combi-Blocks | MFCD00061613 | 397.174 | C13H17BrO9 | 97.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 1g | 117564446](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000472755.jpg-250.jpg)
eMolecules 21085-72-3 | Acetobromo-alpha-D-glucuronic acid methyl ester | Combi-Blocks | MFCD00061613 | 397.174 | C13H17BrO9 | 97.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 1g | 117564446
Acetobromo-alpha-D-glucuronic acid methyl ester | Combi-Blocks | 21085-72-3 | MFCD00061613 | 397.174 | C13H17BrO9 | 97.000 | COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O | 1g | 117564446
Medchemexpress LLC Bet bromodomain inhibitor 4 | 2407658-41-5 | ≥98.0% | 518.59 g/mol | C27H31FN8O2 | 10 MG
BET bromodomain inhibitor 4 is a small-molecule inhibitor of BET family bromodomain epigenetic reader domains supplied for research use as a 10 mg powder. It is used in preclinical studies to probe BET-mediated epigenetic regulation and assay bromodomain interactions.
- Inhibits BET bromodomain activity.
- Intended for research use only.
- Supplied as a 10 mg powder for laboratory applications.
- Target: epigenetic reader domain (BET bromodomain).
- CAS number: 2407658-41-5.
- Molecular formula: C27H31FN8O2; molecular weight: 518.59 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Sigma Aldrich Fine Chemicals Biosciences Heparin SepharoseR 6 Fast
Heparin Sepharose(R) 6 Fast Flow is a well established BioProcess affinity medium designed for capture or intermediate purification steps. This medium is extensively used for industrial purification of several marketed plasma proteins.Heparin Sepharose(R) 6 Fast Flow is a member of the Cytiva range of affinity chromatography media for capture and intermediate purification.Heparin Sepharose(R) 6 Fast Flow is composed of cross-linked 6% agarose beads modified sodium heparin. Immobilization is performed using chemically stable and oriented coupling giving high binding capacity. The chemical stability of the media is solely dictated by the heparin ligand.This medium allows for fast and reliable separations of biomolecules with an affinity for heparin including antithrombin III coagulation factors and other plasma proteins. Additional applications include DNA binding proteins lipoproteins protein synthesis factors enzymes that act on nucleic acids and steroid receptors.Heparin Sepharo