Fatty acid esters
Selleck Chemical LLC 4-Octyl Itaconate
4-Octyl Itaconate activates Nrf2 signaling to inhibit the production of pro-inflammatory cytokines in human macrophages and systemic lupus erythematosus (SLE) patient-derived PBMCs
Medchemexpress LLC Succinate/succinate receptor antagonist 1 | 2361972-29-2 | C17H15N3O | 100 MG
Succinate/succinate receptor antagonist 1 is an antagonist of the succinate/succinate receptor. It can inhibit the activation of succinate receptor 1 (SUCNR1) and block succinate signaling in gingival tissue. This compound can be used for the study of periodontal disease. In vitro, at 10 μM for 24 hours, it significantly inhibits SUCNR1 activation and blocks succinate-mediated receptor signaling in human SUCNR1 AequoScreen cells.
- Inhibits activation of succinate receptor 1 (SUCNR1)
- Blocks succinate signaling in gingival tissue
- Useful for the study of periodontal disease
Medchemexpress LLC Isopropyl myristate | 110-27-0 | MFCD00008982 | 98.0% | 270.45 g/mol | C17H34O2 | 25G
Isopropyl myristate is a fatty acid ester used as a solvent, emollient, and penetration enhancer in formulation and laboratory applications. The reagent is supplied as a liquid with typical purity 98.0% and is suitable as an excipient, analytical standard, or solvent for biochemical assays and formulation research.
- Purity 98.0%.
- Appearance colorless to light yellow liquid.
- Chemical formula C17H34O2; molecular weight 270.45 g/mol.
- Density 0.85 g/cm3.
- Solubility in DMSO 100 mg/mL; ultrasonic aid recommended.
- Storage (pure) -20°C for 3 years or 4°C for 2 years.
Medchemexpress LLC Methyl laurate | 111-82-0 | 214.34 | 500 G
Methyl laurate, also known as methyl dodecanoate, is an esterified 12-carbon saturated fatty acid. It appears as a colorless to light yellow liquid with a density of 0.87 g/cm³. This chemical is intended for laboratory research and substance manufacturing.
- Esterified 12-carbon saturated fatty acid
- Colorless to light yellow liquid appearance
- Density of 0.87 g/cm³
- Melting/freezing point: 4-5°C
- Boiling point: 263°C at 760 mmHg
- Flash point: 110°C
- Stable under recommended storage conditions
- For research use only
Selleck Chemical LLC Methyl acetoacetate S3091-100mg
Methyl acetylacetate (MAA Acetoacetate methyl ester Methyl 3-oxobutanoate Methyl 3-oxobutyrate Methyl acetoacetate Methyl acetylacetate) an endogenous metabolite is used as a chemical reagent used in the synthesis of pharmaceuticals
Medchemexpress LLC Succinate/succinate receptor antagonist 1 | 2361972-29-2 | C17H15N3O | 25 MG
Succinate/succinate receptor antagonist 1 is an antagonist of the succinate/succinate receptor. It can inhibit the activation of succinate receptor 1 (SUCNR1) and block succinate signaling in gingival tissue. This compound can be used for the study of periodontal disease.
- Antagonist of the succinate/succinate receptor.
- Inhibits the activation of succinate receptor 1 (SUCNR1).
- Blocks succinate signaling in gingival tissue.
- Useful for the study of periodontal disease.
- Purity: 99.40%.
- Appearance: Solid, white to off-white.
- For research use only.
Cayman Chemical Betamethason 17-valerate 100mg
A glucocorticoid with anti-inflammatory activity; inhibits the binding of the radiolabeled glucocorticoid dexamethasone to human epidermis and mouse skin (IC50s = 5 and 6 nM, respectively); topical application of a 0.12% ointment blocks increases in EAr weight in a rat model of EAr edema induced by croton oil
Selleck Chemical LLC Ribociclib succinate S5188-25mg
Ribociclib (LEE011) succinate is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively
Medchemexpress LLC Chlorothalonil | 1897-45-6 | MFCD00045594 | 250 MG
Chlorothalonil is a broad-spectrum foliar fungicide with oral activity. It can be used to combat fungal diseases in vegetable and crop leaves. It can alter the microbial community in the soil. Chlorothalonil inhibits spermatogenesis, and can cause intestinal epithelial barrier dysfunction and fetal toxicity.
- Broad-spectrum foliar fungicide
- Oral activity
- Can be used to combat fungal diseases in vegetable and crop leaves
Medchemexpress LLC Hexanoic acid, 3-oxo-, ethyl ester | 3249-68-1 | MFCD00009401 | 96.0% | 158.20 g·mol⁻1 | C8H14O3 | 50 G
Ethyl butyrylacetate (ethyl 3-oxohexanoate) is a ketoester used as a research reagent and synthetic intermediate in organic chemistry, offering a fruity aroma profile and reactivity useful for building complex molecules.
- Useful synthetic building block for organic synthesis
- Commonly used as a flavor and fragrance intermediate
- Purity approximately 96.0% suitable for research applications
- Molecular weight 158.20 g·mol⁻1; formula C8H14O3
- Store at low temperature for extended stability (recommend -20°C)
Cayman Chemical Lauric Acid Leelamide
Lauric acid leelamide is the lauric (C-12) amide analog of leelamine. Leelamine has weak affinity for the human CB1 and CB2 receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.{14127} Leelamine inhibits PDHK with an IC50 value of 9.5 µM.{14105} Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of PLA2 activity from a variety of sources.{14107} There are no published studies of the pharmacological properties of lauric acid leelamide.
Cayman Chemical 3-hydroxy LaurIc AcId 10mg
A hydroxy fatty acid; found in bacteria as well as Pseudosuberites and D. calyx sea sponges; antifungal activity against a panel of seven fungi (MICs = 10-50 μg/ml); partial agonist of GPR84 receptors in vitro (EC50 = 5.24 μM)
Apexbio Technology LLC Betamethasone Valerate 2152-44-5 10mM (in 1mL DMSO)
Betamethasone valerate (CAS 2152-44-5) is a small-molecule agonist targeting the glucocorticoid receptor It is designed to modulate inflammatory responses by altering gene transcription thereby regulating immune-mediated processes Betamethasone valerate exerts its biological activity primarily through glucocorticoid receptor agonism In in vitro studies betamethasone valerate inhibits radiolabeled glucocorticoid (dexamethasone) binding to human epidermis and mouse skin with IC50 values of 5 and 6 nM respectively Based on these pharmacological properties betamethasone valerate holds research potential in dermatological applications including investigations of recurrent aphthous stomatitis and inflammatory skin disorders
Medchemexpress LLC Succinate/succinate receptor antagonist 1 | 2361972-29-2 | C17H15N3O | 50 MG
Succinate/succinate receptor antagonist 1 is an antagonist of the succinate/succinate receptor. It effectively inhibits the activation of succinate receptor 1 (SUCNR1) and blocks succinate signaling in gingival tissue, making it suitable for the study of periodontal disease.
- Antagonist of the succinate/succinate receptor
- Inhibits SUCNR1 activation
- Blocks succinate signaling in gingival tissue
- Can be used for the study of periodontal disease
- Inhibits succinate-mediated receptor signaling in human SUCNR1 AequoScreen cells
Selleck Chemical LLC 4-Octyl Itaconate
4-Octyl Itaconate activates Nrf2 signaling to inhibit the production of pro-inflammatory cytokines in human macrophages and systemic lupus erythematosus (SLE) patient-derived PBMCs