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Filtered Search Results
Apexbio Technology LLC Megestrol Acetate 595-33-5 5g
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
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Apexbio Technology LLC Prednisolone Acetate 52-21-1 10mM (in 1mL DMSO)
Prednisolone acetate (52-21-1) is a synthetic glucocorticoid derivative targeting glucocorticoid receptors (GR) It is designed to modulate GR-mediated signaling pathways thereby regulating inflammatory and immune response gene expression Prednisolone acetate exerts its biological activity primarily through binding to cytosolic GR forming complexes that translocate into the nucleus to modulate transcriptional events related to inflammation and immune function Based on these pharmacological properties prednisolone acetate holds research potential in the investigation of inflammatory and allergic responses immune regulation and transcriptional modulation in experimental models of chronic inflammation
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Medchemexpress LLC Abiraterone acetate | 154229-18-2 | 99.9% | C26H33NO2 | 100 MG
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Abiraterone acetate is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. It is an ester prodrug of Abiraterone, an anticancer agent that inhibits key enzymes involved in steroidogenesis.
- Potent, selective, and irreversible inhibitor of CYP17A1.
- Exhibits antiandrogen activity.
- Functions as an ester prodrug of Abiraterone.
- Inhibits 17,20-lyase and 17α-hydroxylase.
- Suppresses proliferation of AR-positive prostate cancer cell lines.
- Blocks synthesis of 5α-dione and DHT.
- Inhibits CRPC progression and prolongs survival in castration-resistant prostate cancer.
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Medchemexpress LLC Ziconotide acetate (SNX-111 acetate) | 914454-03-8 | 99.2% | 2639.13 (free base) | 1 MG
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Ziconotide acetate (SNX-111 acetate) | 914454-03-8 | 99.2% | 2639.13 (free base) | 1 MG
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Medchemexpress LLC CGGK acetate | 96.78% | 363.43 (free acid) | 1 MG
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CGGK acetate is a control peptide of CAQK peptide, intended for research use only. It presents as a white to off-white solid with a purity of 96.78% and a molecular weight of 363.43 (free acid). Its chemical formula is C13H25N5O5S.xC2H4O2. This product is shipped at room temperature and requires sealed storage, away from moisture.
- Sequence: Cys-Gly-Gly-Lys
- Purity: 96.78%
- Solubility in DMSO: ≥ 100 mg/mL
- Powder storage: -80°C for 2 years, or -20°C for 1 year
- In solvent storage: -80°C for 6 months, or -20°C for 1 month
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Medchemexpress LLC AKN-028 acetate | 98.4% | 362.39 | 50 MG
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AKN-028 acetate is a novel tyrosine kinase (TK) inhibitor. It is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. It inhibits FLT3 autophosphorylation and induces a dose-dependent cytotoxic response (mean IC50=1 μM). It also induces apoptosis by activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML).
- Novel tyrosine kinase (TK) inhibitor
- Potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM
- Inhibits FLT3 autophosphorylation
- Induces a dose-dependent cytotoxic response (mean IC50=1 μM)
- Induces apoptosis by activation of caspase 3
- Can be used in research of acute myeloid leukemia (AML)
- Inhibits growth of primary AML and MV4-11 cells in mice
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Medchemexpress LLC Megestrol acetate (Standard) | 595-33-5 | 98.5% | 384.51 | 50 MG
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Megestrol acetate (Standard) is the analytical standard of Megestrol acetate, intended for research and analytical applications. It is a synthetic and orally active progesteronal agent. This product is effective as an appetite stimulant for wasting syndromes like cachexia and decreases nuclear and cytosol androgen receptors in human BPH tissue. It also has potential for HIV study and downregulates the autophagic catabolic pathway.
- Effective as an appetite stimulant for wasting syndromes
- Decreases nuclear and cytosol androgen receptors in human BPH tissue
- Potential for HIV study
- Downregulates the autophagic catabolic pathway
- Suitable for qualitative, quantitative, and methodological research in HPLC, GC, and MS
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Medchemexpress LLC Flecainide acetate | 54143-56-5 | MFCD00214290 | 99.4% | 474.39 g/mol | C19H24F6N2O5 | 10 MG
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Flecainide acetate is a class 1C antiarrhythmic research reagent that inhibits cardiac Nav1.5 sodium channels. Supplied as a white to off-white solid for laboratory use; intended for research use only and not for human or clinical use.
- Class 1C antiarrhythmic agent that blocks Nav1.5 sodium channels.
- Supplied as a white to off-white solid suitable for analytical and biological research.
- High purity of 99.4%.
- Molecular formula C19H24F6N2O5; molecular weight 474.39 g/mol.
- Available in small research pack sizes, including 10 mg.
- Store solid at 4°C; store solutions at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC Rezafungin acetate 10mM 1mL | 1631754-41-0 | 10MM 1ML
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Rezafungin acetate (Biafungin acetate) is a next-generation broad-spectrum and long-lasting echinocandin Rezafungin acetate shows potent antifungal activity against Candida spp Aspergillus spp and Pneumocystis spp [1 [2
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Medchemexpress LLC Mafenide (Acetate) | 13009-99-9 | 99.3% | 50 MG
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Mafenide Acetate is a potent sulfonamide antimicrobial agent that demonstrates antibacterial activity against *Staphylococcus aureus* and *Pseudomonas aeruginosa*, and antifungal activity against filamentous fungi (e.g., *Lichtheimia* and *Aspergillus flavus*). It is used in research for skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds.
- Potent sulfonamide antimicrobial agent
- Exhibits antibacterial activity against *Staphylococcus aureus* and *Pseudomonas aeruginosa*
- Shows antifungal activity against filamentous fungi
- Used in research for skin grafts on burn wounds
- Applicable for post-traumatic invasive fungal infections
- Used in research for bacterially contaminated wounds
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Apexbio Technology LLC Megestrol Acetate 595-33-5 10mM (in 1mL DMSO)
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
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AdipoGen Thionin acetate salt
Chemical. CAS 78338-22-4. Formula C12H9N3S . C2H4O2. MW BD9837. Thionin acetate is a strongly staining metachromatic dye that is widely used for biological staining, especially in histology. Thionine can be used in place of Schiff reagent in quantitative Feulgen staining of DNA or to mediate electron transfer in microbial fuel cells. It is also employed as a general nuclear stain for chromatin and mucin or for staining Nissl granules by end-point buffering and for showing malignant cells in frozen biopsy sections. Spectral data Absorbance ~597-601 nm.
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Medchemexpress LLC Geranyl acetate | 105-87-3 | 10 G
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Geranyl acetate is an acyclic monoterpene ester derived from geraniol. It is widely used in the cosmetics industry due to its pleasant scent and can induce cell apoptosis.
- Purity: 99.74%
- Molecular weight: 196.29
- Formula: C12H20O2
- Appearance: Liquid (density: 0.916 g/cm³)
- Color: Colorless to light yellow
- Initial source: Plants (Gramineae, Cymbopogon flexuosus)
- Solubility (in vitro): 100 mg/mL in DMSO
- Induces cell apoptosis
- Anti-cancer activity against colo-205 cancer cells (IC50: 30 μM)
- Apoptosis in colo-205 cells linked to Bax upregulation and Bcl-2 downregulation
- HEK293 EC50: 25.8 μM (agonist at rat TRPA1)
- HEK293 IC50: 21.2 μM (antagonist at rat TRPA1)
- HEK293 IC50: > 100 μM (antagonist at human TRPV1 and rat TRPM8)
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Medchemexpress LLC (+)-Bornyl acetate | 20347-65-3 | MFCD00135942 | 98.0% | 196.29 g·mol⁻¹ | C12H20O2 | 10 MG
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(+)-Bornyl acetate is a naturally occurring monoterpene ester found in pichtae (Siberian fir needle) essential oil. Supplied as a research-grade reagent with reported biological activity including inhibition of Arabidopsis root growth, it is used in aroma, flavor, and plant physiology studies. Typical properties include CAS 20347-65-3, molecular formula C12H20O2, molecular weight 196.29 g·mol⁻¹, and reported purity 98%.
- Natural monoterpene ester found in fir needle essential oil.
- Reported to inhibit root growth in Arabidopsis seedlings.
- High purity suitable for research applications (98%).
- Supplied in small, precise quantities appropriate for analytical and biological assays.
- Volatile aroma compound with applications in flavor and fragrance research.
- Applicable to plant physiology and bioactivity studies.
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Apexbio Technology LLC Nafarelin Acetate 76932-56-4 50mg
Nafarelin Acetate is a synthetic agonist targeting gonadotropin-releasing hormone (GnRH) receptors It is designed to modulate the hypothalamic-pituitary-gonadal axis by initially stimulating and subsequently downregulating GnRH receptors in the pituitary gland thereby suppressing secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) Nafarelin Acetate exerts its biological activity primarily through receptor downregulation and suppression of pituitary hormone release Based on these pharmacological properties Nafarelin Acetate holds research potential in the investigation of endocrine signaling pathways associated with reproductive development disorders including central precocious puberty and endometriosis
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