Steroids and derivatives
Medchemexpress LLC Guaiacol-d3 (2-Methoxyphenol-d3) | 74495-69-5 | 127.16 | 100 MG
Guaiacol-d3 is the deuterium-labeled Guaiacol, a phenolic compound known for its anti-inflammatory activity. It achieves this by inhibiting LPS-stimulated COX-2 expression and NF-κB activation. This stable isotope can also serve as a tracer and an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS.
- Stable isotope.
- Intended for research purposes.
- Exhibits anti-inflammatory activity.
- Can be utilized as a tracer and internal standard for quantitative analysis.
Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 1 G
Glycocholic acid is an endogenous metabolite and a bile acid that exhibits anticancer activity by targeting both pump resistance-related and non-pump resistance-related pathways. It is suitable for research applications.
- Bile acid with anticancer activity.
- Targets pump resistance-related pathways.
- Targets non-pump resistance-related pathways.
- Increases cytotoxicity and intracellular accumulation of epirubicin in Caco-2 cells.
- Increases absorption of epirubicin in rat small intestine.
- Intensifies epirubicin-induced apoptosis.
- Downregulates MDR1, MRP1, and MRP2 mRNA expression.
- Suppresses Bcl-2 mRNA and induces Bax mRNA.
- Increases Bax-to-Bcl-2 ratio and mRNA levels of p53, caspase-9 and -3.
- Exhibits agonist activity on TGR5 in CHO cells (EC50 = 13.6 μM).
- Inhibits E217betaG uptake in MRP4-expressing HEK293 cells (IC50 = 400 μM).
Medchemexpress LLC Glycocholic acid-d5 | 2170091-95-7 | 470.65 | 1 MG
Glycocholic acid-d5 is the deuterium labeled Glycocholic acid, which is a bile acid exhibiting anticancer activity by targeting both pump resistance-related and non-pump resistance-related pathways. This compound is intended for research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Abcam 20-Hydro x yecdysone (Ecdysterone), Steroid invertebrate hormone, 25MG
MW 480.6 Da, Purity >98%. Steroid invertebrate hormone. Regulates molting, metamorphosis and reproduction in arthropods. Neuroprotective against oxidative stress in mammals. Inhibits NF-κB activation and iNOS expression. Antioxidant and apoptotic agent.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Estrone 3-(beta-D-glucuronide) sodium salt | 15087-01-1 | MFCD00271561 | 25MG
Estrone 3-(beta-D-glucuronide) sodium salt | Purity: >=99% (HPLC) | Mol Wt: 468.47 | 15087-01-1 | MFCD00271561 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Estrone 3-(beta-D-glucuronide) sodium salt | 15087-01-1 | MFCD00271561 | 100MG
Estrone 3-(beta-D-glucuronide) sodium salt | Purity: >=99% (HPLC) | Mol Wt: 468.47 | 15087-01-1 | MFCD00271561 | 100MG
Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.
- Potent farnesoid X receptor (FXR) antagonist.
- Induces apoptosis in multiple cancer cell lines.
- Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
- Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
- Suitable for biochemical and signaling pathway research applications.
Cayman Chemical HyodeoxycholIc ACD MaxSpec
A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
Sigma Aldrich Fine Chemicals Biosciences Estrone 3-(beta-D-glucuronide) sodium salt | 15087-01-1 | MFCD00271561 | 5MG
Estrone 3-(beta-D-glucuronide) sodium salt | Purity: >=99% (HPLC) | Mol Wt: 468.47 | 15087-01-1 | MFCD00271561 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Taurocholic Acid Sodium Salt Hydrate | 345909-26-4 | MFCD00150819 | 100g
Taurocholic Acid Sodium Salt Hydrate | Purity: 95% | Mol Wt: 537.68 (anhydrous basis) | 345909-26-4 | MFCD00150819 | 100g
Sigma Aldrich Fine Chemicals Biosciences Dexamethasone | 50-02-2 | MFCD00064136 | 500mg
Dexamethasone | Purity: 97% | Mol Wt: 392.46 | 50-02-2 | MFCD00064136 | 500mg
Sigma Aldrich Fine Chemicals Biosciences 1alpha,25-Dihydroxyvitamin D3 >=97.0% (HPLC) | 32222-06-3 | MFCD00867079 | 100UG
1alpha,25-Dihydroxyvitamin D3 >=97.0% (HPLC) | Purity: >=97.0% (HPLC) | Mol Wt: 416.64 | 32222-06-3 | MFCD00867079 | 100UG
Sigma Aldrich Fine Chemicals Biosciences 6alpha-Methylprednisolone 21-hemisuccinate sodium salt lyophilized powder | 2375-03-3 | MFCD00152612 | 25MG
6alpha-Methylprednisolone 21-hemisuccinate sodium salt lyophilized powder | Purity: >=98.00% (TLC) | Mol Wt: 496.53 | 2375-03-3 | MFCD00152612 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Hydrocortisone Impurity L50MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
eMolecules estra-1(10),2,4-triene-3,16,17-triol | 50-27-1 | MFCD00668446 | 25mg
Oakwood Chemical | estra-1(10),2,4-triene-3,16,17-triol | 25mg | 537722281 | 373692 | | 50-27-1 | MFCD00668446 | 288.387 | C18H24O3
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