Purine nucleotides
Medchemexpress LLC Tenofovir diphosphate (disodium) | 2738719-07-6 | 99.4% | 491.14 | 25 MG
Tenofovir diphosphate disodium is an antiretroviral agent that acts as an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). It can be used for AIDS research.
- Antiretroviral agent
- Inhibits HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM)
- Used for AIDS research
- Exhibits little inhibitory effect on eukaryotic DNA replication (1-2500 μM, 18-32 min)
Medchemexpress LLC Motesanib diphosphate | 857876-30-3 | MFCD12407403 | >98.0% | 569.44 | C22H29N5O9P2 | 50 MG
Motesanib diphosphate is the diphosphate salt of motesanib, an ATP-competitive small-molecule inhibitor of VEGF receptors used as a research reagent for kinase and signaling studies.
- ATP-competitive inhibitor of VEGFR1/2/3 with low-nanomolar potency.
- Diphosphate salt form improves aqueous solubility for in vitro applications.
- Molecular weight 569.44; formula C22H29N5O9P2.
- High solubility in DMSO (≥110 mg/mL) and moderate solubility in water (≈5 mg/mL with warming).
- Intended for research and analytical use; not for human or clinical use.
Cambridge Isotope Laboratories Uridine diphosphate-Alpha-D-glucose NH4 salt (glucose-1 2 3 4 5 6 -13C6 99%) in solution CP 95% 100 umol
Uridine diphosphate-Alpha-D-glucose NH4 salt (glucose-1 2 3 4 5 6 -13C6 99%) in solution CP 95% 100 umol
![eMolecules Adenosine-3?,5?-cyclic-13C5 Monophosphate | Toronto Research Chemicals | | | 334.171 | C10H12N5O6P | 95.000 | Nc1ncnc2n(cnc12)[13C@@H]1O[13C@@H]2[13CH2]OP(O)(=O)O[13C@H]2[13C@H]1O | 5mg | 483376524](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3070026.JPG-250.jpg)
eMolecules Adenosine-3?,5?-cyclic-13C5 Monophosphate | Toronto Research Chemicals | | | 334.171 | C10H12N5O6P | 95.000 | Nc1ncnc2n(cnc12)[13C@@H]1O[13C@@H]2[13CH2]OP(O)(=O)O[13C@H]2[13C@H]1O | 5mg | 483376524
Adenosine-3?,5?-cyclic-13C5 Monophosphate | Toronto Research Chemicals | | | 334.171 | C10H12N5O6P | 95.000 | Nc1ncnc2n(cnc12)[13C@@H]1O[13C@@H]2[13CH2]OP(O)(=O)O[13C@H]2[13C@H]1O | 5mg | 483376524
Medchemexpress LLC Adenosine 5'-β-thiodiphosphate trilithium salt | 73536-95-5 | MFCD00077314 | 94.9% | 461.07 g·mol⁻¹ | C10H12Li3N5O9P2S | 5 MG
ADP-β-S trilithium is the trilithium salt form of adenosine 5'-β-thiodiphosphate used as a research reagent to activate P2Y12 receptors and study purinergic signaling and inflammatory pathways. It modulates cytokine production and NF-κB/NLRP3 signaling, and is provided as a dry powder for laboratory use.
- Activates P2Y12 receptor to modulate purinergic signaling.
- Increases IL-1β and IL-6 production in microglial cells.
- Promotes NF-κB phosphorylation and nuclear translocation.
- Enhances NLRP3 inflammasome activation.
- Supplied with stated purity and molecular data for experimental planning.
- Suitable for biochemical and cellular assays requiring receptor activation.
Apexbio Technology LLC Chloroquine diphosphate 50-63-5 10mM (in 1mL H2O)
Chloroquine diphosphate is an antimalarial agent and inhibitor of TLR7 and TLR9 commonly used in biomedical research to modulate autophagic processes On the cellular level chloroquine diphosphate promotes autophagy through cell cycle arrest at the G1 phase involving increased expression of p27 and p53 and decreased levels of CDK2 and cyclin D1 Additionally chloroquine diphosphate enhances sensitivity of cancer cells toward chemotherapy and radiotherapy treatments by elevating autophagy and apoptotic responses In vitro studies demonstrated dose-dependent activity with reported IC50 values typically ranging from approximately 15 to 40 M depending on cell types This compound is widely utilized as an autophagy modulator and therapeutic adjuvant in tumor cell models
Medchemexpress LLC Motesanib diphosphate | 857876-30-3 | MFCD12407403 | 99.9% | 569.44 g/mol | C22H29N5O9P2 | 5 MG
Motesanib diphosphate is the diphosphate salt of motesanib, an ATP-competitive inhibitor of VEGFR1/2/3 and c-Kit, supplied for laboratory research and analytical applications.
- Potent ATP-competitive inhibitor of VEGFR1/2/3 and c-Kit.
- Molecular formula: C22H29N5O9P2.
- Molecular weight: 569.44 g/mol.
- Pack size: 5 mg.
- Solubility: DMSO ≥ 110 mg/mL; H2O 5 mg/mL (with ultrasonic warming).
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC Cytidine diphosphate-13C9,15N3 dilithium | 63-38-7 | 99.7% | 426.96 | 1 MG
Cytidine diphosphate-13C9,15N3 dilithium is 13C and 15N-labeled Cytidine diphosphate. It is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis. This product is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cidofovir diphosphate tri(triethylamine) | 00-00-0 | 99.9% | 742.72 g/mol | C26H61N6O12P3 | 5 MG
Cidofovir diphosphate tri(triethylamine) is the triethylamine salt of cidofovir diphosphate, an active intracellular metabolite and selective inhibitor of viral DNA polymerases. It is provided as a high-purity biochemical reagent intended for in vitro and biochemical research applications.
Apexbio Technology LLC Primaquine Diphosphate 63-45-6 10g
Primaquine Diphosphate is an 8-aminoquinoline derivative utilized primarily as an antimalarial agent targeting the extraerythrocytic liver stage of malaria parasites While its precise IC50 values remain unspecified primaquine s biological activity involves interference with nucleic acid function subsequently disrupting protein synthesis pathways and lipid biosynthesis and inducing membrane disturbances In vitro primaquine has been applied in cell culture models to investigate antiviral effects demonstrating dose-dependent inhibition of Newcastle disease virus replication and modulation of viral RNA synthesis In vivo experiments using radiolabeled primaquine-loaded liposomes in murine models illustrate pronounced hepatic accumulation Clinically this compound is employed as prophylaxis against malaria infections (e g Plasmodium falciparum and P vivax)
Sigma Aldrich Fine Chemicals Biosciences Chloroquine diphosphate sa250G
Chloroquine is a member of quinolone family and is a weak intercalating agent. Chloroquine is used for treating amebiasis rheumatoid arthritis discoid and systemic lupus erythematosus.