Purine nucleotides
Crescent Chemical Co Inc ATP NA2 SALT CRYS RESEARCH GRD
Adenosine-5'-triphosphate-Na2-salt cryst. research grade Size - 25G Storage Conditions - -15 °C TO -25 °C Catalog Number - 10920.03 CAS 987-65-5
Apexbio Technology LLC 8-AZIDO-ATP 10UL 100 MM
8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity
Apexbio Technology LLC 2-O-METHYL-ATP 50UL 100 MM
2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
Apexbio Technology LLC 2-AMINO-ATP 10UL 100 MM
2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
Apexbio Technology LLC 8-Aza-ATP 50ul (100 mM)
8-Aza-ATP is a structural analog of ATP characterized by the substitution of the carbon atom at the 8-position of the purine ring with nitrogen resulting in an 8-azapurine nucleotide moiety Due to this structural alteration 8-Aza-ATP competitively interacts with ATP-binding sites on enzymes thereby modulating their catalytic activities This compound serves as a tool in biochemical research to elucidate enzyme-substrate recognition nucleotide binding specificity and catalytic mechanisms of ATP-dependent enzymes Additionally it is utilized in the study of cellular energy metabolism signal transduction pathways and nucleotide-mediated regulatory processes contributing to understanding relevant physiological and pathological mechanisms