Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Ademetionine disulfate tosylate United States Pharmacopeia (USP) Reference Standard | 97540-22-2 | 500MG
Ademetionine disulfate tosylate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 766.8 | 97540-22-2 | 500MG
Medchemexpress LLC Ganciclovir | 82410-32-0 | 99.9% | 1 G
Ganciclovir (BW 759) is a nucleoside analogue and an orally active antiviral agent effective against CMV. It also exhibits in vitro activity against members of the herpes group and some other DNA viruses, including human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22, and 28. It has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain.
- Nucleoside analogue
- Orally active antiviral agent
- Effective against CMV, HSV, and some other DNA viruses
- Inhibits in vitro replication of human herpes viruses (HSV 1 and 2, CMV)
- Inhibits in vitro replication of adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22, and 28
- IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)
- Can diffuse into the brain
Cayman Chemical S-CrIzotInIb 10mg
An MTH1 inhibitor (IC50 = 72 nM); selective for MTH1 over a panel of 456 kinases at 1 µM; induces oxidative DNA damage and apoptosis in SGC-7901 and BGC-823 cancer cells at 30 µM; induces ROS production and apoptosis in the same model; inhibits proliferation in a panel of 14 cancer cell lines expressing wild-type or various mutant forms of K-Ras or p53 (IC50s = 0.52-7.4 µM); inhibits tumor growth in an SW 480 mouse xenograft model at 25 mg/kg
Medchemexpress LLC Itacitinib | 1334298-90-6 | 99.97% | 553.51 | 25 MG
Itacitinib is an orally active and selective inhibitor of JAK1 with an IC50 of 2 nM for human JAK1. It shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2. Itacitinib is used in the research of myelofibrosis.
- Orally active
- Selective inhibitor of JAK1
- High selectivity over JAK2, JAK3, and TYK2
- Used in the research of myelofibrosis
Sigma Aldrich Fine Chemicals Biosciences Methyclothiazide United States Pharmacopeia (USP) Reference Standard | 135-07-9 | 200MG
Methyclothiazide United States Pharmacopeia (USP) Reference Standard | Mol Wt: 360.24 | 135-07-9 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Metoclopramide impurity A European Pharmacopoeia (EP) Reference Standard | 5608-13-9 |
Metoclopramide impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 341.83 | 5608-13-9 |
Apexbio Technology LLC Fluticasone propionate 80474-14-2 10mg
Fluticasone propionate is a synthetic glucocorticoid receptor (GR) agonist with high receptor selectivity and affinity It exerts anti-inflammatory and immunosuppressive actions by interacting with intracellular GR thereby influencing gene expression pathways and downstream cytokine responses This compound has been widely utilized in biomedical research to study inflammatory signaling mechanisms glucocorticoid receptor mediated transcriptional regulation and immune responses associated with asthma allergic rhinitis and related inflammatory diseases Reported in vitro studies demonstrate fluticasone propionate s GR agonist activity with an IC50 value in the subnanomolar range (approximately 0 5 nM) supporting its frequent utilization as a standard GR agonist in receptor-binding assays and inflammation-related experiments
Medchemexpress LLC Cefteram pivoxil | 82547-81-7 | 98.2% | 593.6 g/mol | C22H27N9O7S2 | 10 MG
Cefteram pivoxil is an orally active cephalosporin antibiotic prodrug of cefteram, used in research on bacterial infections. Provided as a purified chemical standard for laboratory studies, it is intended for research use only.
- Orally active cephalosporin antibiotic prodrug.
- Suitable for in vitro and in vivo bacterial infection studies.
- High purity (98.18%) for analytical and experimental use.
- Available in small-quantity packs for research flexibility.
- Molecular weight 593.6 g/mol; formula C22H27N9O7S2.
- CAS number 82547-81-7 for unambiguous identification.
Medchemexpress LLC Carteolol hydrochloride | 51781-21-6 | 99.6% | 328.8343 | 5 MG
Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma, as well as an anti-arrhythmia, anti-angina, and antihypertensive agent. It has a protective action against UVB-induced HCEC damage, with its radical scavenging ability potentially being an important basis for this effect. A new alginate formulation of long-acting carteolol 1% given once daily is as effective as standard 1% carteolol given twice daily, with no significant differences in safety.
- Used to treat glaucoma
- Functions as an anti-arrhythmia agent
- Acts as an anti-angina agent
- Serves as an antihypertensive agent
- Protective action against UVB-induced HCEC damage
- Radical scavenging ability
Medchemexpress LLC Imatinib | 152459-95-5 | MFCD00868202 | C29H31N7O | 500 MG
Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR, and c-kit kinase activity. It functions by binding near the ATP binding site, which locks the kinase in a closed or self-inhibited conformation, thereby semicompetitively inhibiting the enzyme activity of the protein. Additionally, Imatinib is an inhibitor of SARS-CoV and MERS-CoV.
- Selectively inhibits BCR/ABL, v-Abl, PDGFR, and c-kit kinase activity.
- Functions by binding near the ATP binding site.
- Inhibits enzyme activity of the protein semicompetitively.
- Inhibitor of SARS-CoV and MERS-CoV.
- For research use only.
Medchemexpress LLC Tofacitinib | 477600-75-2 | 99.9% | 312.37 | 100 MG
Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively. It is intended for research use only.
- Inhibits JAK3 with an IC50 of 1 nM
- Inhibits JAK2 with an IC50 of 20 nM
- Inhibits JAK1 with an IC50 of 112 nM
Sigma Aldrich Fine Chemicals Biosciences rGlucagon, recombinant glucagon (human) United States Pharmacopeia (USP) Reference Standard | 16941-32-5 | 2X2.94MG
rGlucagon, recombinant glucagon (human) United States Pharmacopeia (USP) Reference Standard | Mol Wt: 3482.75 | 16941-32-5 | 2X2.94MG
Medchemexpress LLC Imatinib acid | 2741007-77-0 | 99.7% | 551.64 g/mol | C31H33N7O3 | 5 MG
Imatinib acid is a research-grade small-molecule analogue of imatinib (CAS 2741007-77-0) supplied as a solid for laboratory use. It is intended for in vitro pharmacology, analytical reference, and chemical intermediate applications and is not for human or clinical use. Product documentation includes a data sheet and a safety data sheet for handling and storage guidance.
- High purity (99.73%) suitable for analytical and research use.
- Molecular formula C31H33N7O3 and molecular weight 551.64 g/mol.
- Available in small packaged quantities for precise dosing.
- Provided with a safety data sheet and product data sheet.
- Suitable as a reference standard, metabolite, or intermediate in research workflows.
Medchemexpress LLC Econazole nitrate | 24169-02-6 | 98.0% | 1 ML
Econazole nitrate is an imidazole class antifungal medication that also possesses antibacterial activity. It is used as a cream to treat various skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch.
- Imidazole class antifungal medication
- Also has antibacterial activity
- Used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch
- Well tolerated in toxicity and teratogenicity studies in different laboratory animals
Sigma Aldrich Fine Chemicals Biosciences Meloxicam impurity B European Pharmacopoeia (EP) Reference Standard | 7305-71-7 | MFCD00078317 |
Meloxicam impurity B European Pharmacopoeia (EP) Reference Standard | Mol Wt: 114.17 | 7305-71-7 | MFCD00078317 |