Drug Standards
Medchemexpress LLC Keto Ziprasidone | 884305-07-1 | MFCD30747855 | 99.0% | 426.92 | C21H19ClN4O2S | 5 MG
Keto Ziprasidone is a characterized impurity of the antipsychotic ziprasidone supplied for research use only. It is provided as a solid reference standard for analytical, identification, and investigational studies involving serotonin and dopamine receptor antagonists.
- Provides a characterized impurity standard for analytical and identification work.
- CAS number 884305-07-1.
- Molecular formula C21H19ClN4O2S; molecular weight 426.92.
- Purity 98.96% suitable for research applications.
- Solid, off-white to light yellow appearance.
- Storage: powder at -20°C; in solvent at -80°C (6 months) or -20°C (1 month).
- Available in small milligram pack sizes for reference use.
Medchemexpress LLC Enalapril | 75847-73-3 | 99.96% | 100 MG
Enalapril | 75847-73-3 | 99.96% | 100 MG
Medchemexpress LLC Methylprednisolone succinate sodium | 2375-03-3 | 98.5% | 1 ML
Methylprednisolone succinate sodium | 2375-03-3 | 98.5% | 1 ML
Selleck Chemical LLC Verdinexor (KPT-335) 5mg 1392136-43-4 ATG-527
Verdinexor (KPT-335, ATG-527) is an orally bioavailable, selective XPO1/CRM1 inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Poloxamer solid United Sta1G
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Apexbio Technology LLC Meclizine 2HCl 1104-22-9 100mg
Meclizine dihydrochloride (Meclizine 2HCl CAS 1104-22-9) is a small molecule antagonist of histamine H1 receptors commonly investigated for its antiemetic properties In addition to its antihistaminic activity meclizine exhibits antimuscarinic effects and inhibits oxidative phosphorylation It has also been identified as an agonist of the mouse constitutive androstane receptor (mCAR) and demonstrates inverse agonist activity at other signaling pathways These multifunctional pharmacological properties make meclizine 2HCl a useful tool in research exploring receptor-mediated signaling mitochondrial function and metabolism-related diseases
Selleck Chemical LLC Riluzole 50mg 1744-22-5 RP-54274, PK 26124
Riluzole (RP-54274, PK 26124) is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC Naftifine HCl 65473-14-5 50mg
Naftifine HCl (CAS 65473-14-5) is a small-molecule inhibitor targeting squalene 2 3-epoxidase It is designed to inhibit this key enzyme thereby disrupting the fungal sterol biosynthetic pathway Naftifine HCl exerts its biological activity primarily through inhibition of squalene 2 3-epoxidase leading to intracellular squalene accumulation and impairment of fungal membrane formation and integrity In in vitro studies Naftifine HCl demonstrates inhibitory activity with IC50 values generally ranging between 20 100 nM against common dermatophytes and fungal pathogens Based on these pharmacological properties Naftifine HCl holds research potential in studies of fungal infections and sterol synthesis inhibition mechanisms including conditions such as tinea pedis tinea corporis and tinea cruris
Medchemexpress LLC Dabigatran impurity 47 | 2225986-95-6 | 5mg
Dabigatran impurity 47 is an impurity of Dabigatran (HY-10163)
Cayman Chemical -FlurbIprofen 10g
A non-selective COX inhibitor (IC50s = 0.04 and 0.51 μM for COX-1 and COX-2, respectively); reduces carrageenan-induced hind paw edema and yeast-induced fever in rats from 0.3-4.8 mg/kg; reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis; reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model at 5 mg/kg
Selleck Chemical LLC Ganoderic acid A S4753-5mg
Ganoderic Acid A (GAA) is an active triangle compound in Ganoderma Lucidum It can inhibit the JAK-STAT3 signal pathway and inhibit cell proliferation vitality and ROS Ganoderic Acid A has analgesic antioxidant cytotoxicity protecting liver and anti -tumor activity
Selleck Chemical LLC Cilengitidetrifluoroacetate 5mg 199807-35-7 EMD 121974, NSC 707544
Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for ?v?3 receptor and ?v?5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Lenalidomide-PEG1-azide | 2185795-67-7 | MFCD34469882 | 95.8% | 386.36 g·mol⁻¹ | C17H18N6O5 | 5 MG
Lenalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that combines a lenalidomide-derived cereblon-binding moiety with a short PEG1 linker terminating in an azide. It is intended as a building block for PROTAC construction and for bioorthogonal conjugation using copper-catalyzed or strain-promoted azide-alkyne cycloaddition.
- Terminal azide enables CuAAC and SPAAC click chemistry.
- Lenalidomide-derived cereblon ligand for E3 ligase recruitment.
- Short PEG1 linker provides minimal steric bulk.
- High chemical purity suitable for research use.
- Molecular weight 386.36 g·mol⁻¹; CAS 2185795-67-7.
- Available in small-scale quantities for synthesis and screening.
Medchemexpress LLC Doxycycline (monohydrate) | 17086-28-1 | 99.0% | 462.45 | 1 ML
Doxycycline monohydrate is an antibiotic and a broad-spectrum metalloproteinase (MMP) inhibitor. It is intended for research use only.
- Reduces expression of mitochondrial encoded cytochrome c oxidase I (MT-CO1) protein and increases glucose consumption.
- Protects cells from hypoxia-induced glioma cell death at low concentrations.
- Reduces MMP-9 activity and collagen degradation.
- Prevents vascular lesions in heterozygous Col3a1 knockout mouse models.
- Used as an inducer to control gene expression in Tet-On/Tet-Off systems.
- Associated with clinical trials for various conditions.
Apexbio Technology LLC Ketoconazole 65277-42-1 500mg
Ketoconazole (65277-42-1) is a small-molecule inhibitor targeting cytochrome P450-dependent enzymes including cyclosporine oxidase and testosterone 6 -hydroxylase It is designed to inhibit these catalytic activities thereby modulating the oxidative metabolism of clinically relevant substrates Ketoconazole exerts its biological activity primarily through inhibition of cytochrome P450-mediated pathways In in vitro studies ketoconazole demonstrates inhibitory activity with an IC50 of approximately 0 19 mM for cyclosporine oxidase and about 0 22 mM for testosterone 6 -hydroxylase Based on these pharmacological properties ketoconazole holds research potential in studies of drug-drug interactions hepatic enzyme induction and metabolic profiling assays