Drug Standards
Medchemexpress LLC N-acetyl mesalazine | 51-59-2 | 99.9% | C9H9NO4 | 5 MG
N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid and serves as a biomarker for evaluating its efficacy. It can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. This compound can be used in the study of diseases such as colitis and colon cancer.
- Primary intestinal metabolite of 5-aminosalicylic acid
- Serves as a biomarker for evaluating efficacy of 5-aminosalicylic acid
- Scavenges free radicals
- Reduces DNA base hydroxylation
- Ameliorates mucosal inflammation
- Can be used in the study of diseases such as colitis and colon cancer
- Inhibits OH radical-stimulated DNA base hydroxylation in calf thymus DNA
Advanced Chemblocks Inc VX-809; 25MG; 98%
Chemical Name: VX-809 CAS: 936727-05-8 #N/A MDL Number: MFCD16659051 Category: Reference Compound Synonym: VX-809
Sigma Aldrich Fine Chemicals Biosciences Santonin European Pharmacopoeia (EP) Reference Standard | 481-06-1 | MFCD00135865 |
Santonin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 246.3 | 481-06-1 | MFCD00135865 |
Apexbio Technology LLC Granisetron HCl 107007-99-8 100mg
Granisetron HCl (CAS 107007-99-8) is a selective antagonist of the serotonin 5-hydroxytryptamine type 3 (5-HT sub 3 /sub ) receptor By competitively inhibiting 5-HT sub 3 /sub receptor-mediated signaling Granisetron HCl suppresses serotonin-induced activation of the vomiting reflex pathway in both central and peripheral nervous systems This pharmacological activity underlies its utility in preventing and investigating the mechanisms of chemotherapy-induced and postoperative nausea and vomiting Granisetron HCl is widely employed in preclinical and clinical studies to elucidate 5-HT sub 3 /sub receptor function and to explore antiemetic strategies
Selleck Chemical LLC Pirfenidone 10mg 53179-13-8 S-7701,AMR-69
Pirfenidone (S-7701, AMR-69) is an inhibitor for TGF-? production and TGF-? stimulated collagen production, reduces production of TNF-? and IL-1?, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Venlafaxine for system suitability European Pharmacopoeia (EP) Reference Standard | 99300-78-4 | MFCD03658865 |
Venlafaxine for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 313.86 | 99300-78-4 | MFCD03658865 |
Sigma Aldrich Fine Chemicals Biosciences Desosaminylazithromycin United States Pharmacopeia (USP) Reference Standard | 117693-41-1 | 15MG
Desosaminylazithromycin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 590.79 | 117693-41-1 | 15MG
Medchemexpress LLC Raloxifene (hydrochloride) | 82640-04-8 | 99.8% | 510.04 | 1 ML
Raloxifene hydrochloride is a second-generation selective and orally active estrogen receptor modulator. It exhibits estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue.
- Estrogen-agonistic effects on bone and lipid metabolism
- Estrogen-antagonistic effects on uterine endometrium and breast tissue
- For research use only
- Purity of 99.8%
- Stable under recommended storage conditions
Selleck Chemical LLC Cilengitidetrifluoroacetate 5mg 199807-35-7 EMD 121974, NSC 707544
Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for ?v?3 receptor and ?v?5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Alclometasone dipropionate Related Compound A United States Pharmacopeia (USP) Reference Standard | 71868-53-6 | 20MG
Alclometasone dipropionate Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 486.6 | 71868-53-6 | 20MG
Chem-Impex International, Inc. Cefonicid Sodium | 61270-78-8 | MFCD00941437 | 1G
Cefonicid Sodium, 61270-78-8, MFCD00941437, 1G
U.S. Pharmacopeia Ketorolac Related Compound D, 113502-55-9, MFCD27965995, 20 mg
Empirical Formula (Hill Notation): C14H13NO, Molecular Weight: 211.26, Synonym: 5-Benzoyl-2,3-dihydro-1H-pyrrolizine.
Medchemexpress LLC Zileuton sodium | 118569-21-4 | 98.0% | C11H11N2NaO2S | 25 MG
Zileuton sodium is a potent and selective inhibitor of 5-lipoxygenase, exhibiting inflammatory activities. It is for research use only and not sold to patients.
- Potent and selective 5-lipoxygenase inhibitor
- Exhibits inflammatory activities
- White to off-white solid appearance
- High purity (98.02%)
- Suitable for research use only
Medchemexpress LLC Citalopram (hydrobromide) | 59729-32-7 | 1 ML
Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI) with blood-brain barrier permeability. It inhibits 5-HT uptake into synaptosomes and rabbit blood platelets, demonstrating an antidepressant effect. It also exhibits concentration-dependent cytotoxicity on various neuroblastoma cell lines and human primary Schwann cells in vitro.
- Selective serotonin reuptake inhibitor (SSRI)
- Blood-brain barrier permeability
- Inhibits 5-HT uptake into synaptosomes with an IC50 of 1.8 nM
- Inhibits 5-HT uptake in rabbit blood platelets with an IC50 of 14 nM
- Exhibits concentration-dependent cytotoxicity on various neuroblastoma cell lines and human primary Schwann cells in vitro
Medchemexpress LLC Enzastaurin | 170364-57-5 | MFCD11040980 | >98.0% | 515.61 g/mol | C32H29N5O2 | 100 MG
Enzastaurin (LY317615) is a small-molecule research reagent that selectively inhibits protein kinase C beta (PKCβ). It is supplied as a powder for laboratory use and is commonly used in kinase inhibition and cell-signaling studies.
- Potent PKCβ inhibitor with IC50 = 6 nM.
- Shows 6- to 20-fold selectivity over PKCα, PKCγ, and PKCε.
- Molecular formula C32H29N5O2 and molecular weight 515.61 g/mol.
- Provided as a powder suitable for preparing stock solutions.
- Used for kinase signaling, apoptosis, and autophagy research applications.