Drug Standards
Medchemexpress LLC Fenticonazole (nitrate) | 73151-29-8 | 98.9% | 25 MG
Fenticonazole Nitrate is an antifungal imidazole ring derivative that hinders ergosterol integration, destructing the cytoplasmatic outer membrane. It is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis. This azole antifungal drug is used locally as the nitrate in the treatment of vulvovaginal candidiasis and is active against organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.
- Antifungal imidazole ring derivative.
- Operates by hindering ergosterol integration and destructing the cytoplasmatic outer membrane.
- Effective against Gram-positive bacteria, mycoses, and vaginal candidiasis.
- Active against dermatophyte pathogens, Malassezia furfur, and Candida albicans.
Selleck Chemical LLC Felodipine 50mg 72509-76-3 CGH-869
Felodipine (CGH-869) is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Cephalexin Monohydrate S5207-25mg
Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity
Selleck Chemical LLC Racecadotril S2503-50mg
Racecadotril (Acetorphan) is a peripherally acting enkephalinase inhibitor with an IC50 of 4 5 M
Apexbio Technology LLC Sulconazole Nitrate 61318-91-0 50mg
Sulconazole Nitrate (CAS 61318-91-0) is a small-molecule inhibitor targeting the fungal cytochrome P450-dependent enzyme lanosterol 14 -demethylase It is designed to inhibit this enzyme thereby disrupting ergosterol biosynthesis and compromising fungal cell membrane integrity Sulconazole Nitrate exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies Sulconazole Nitrate demonstrates broad-spectrum antifungal inhibition with IC50 values generally ranging between 1 to 10 M depending on fungal species and assay methods Based on these pharmacological properties Sulconazole Nitrate holds research potential in the evaluation of antifungal susceptibility profiles and the study of fungal membrane-associated targets and resistance mechanisms
FUJIFILM BIOSCIENCES INC Valproic Acid | 99-66-1 | MFCD00002672 | 5g
Valproic Acid | Purity: % | Mol Wt: 144.21 | 99-66-1 | MFCD00002672 | 5g
Selleck Chemical LLC Methotrexate 100mg 59-05-2 NCI-C04671
Methotrexate (MTX, NCI-C04671), analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Ibiglustat (succinate) | 1629063-80-4 | 99.7% | 507.57 | 50 MG
Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. It can be utilized for research related to Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
- Orally active.
- Brain-penetrant glucosylceramide synthase (GCS) inhibitor.
- Can be used for research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
Medchemexpress LLC Suplatast (Tosilate) | 94055-76-2 | 499.64 | 50 MG
Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor that inhibits both IL-4 and IL-5 production from Th2 cells and suppresses IgE synthesis. It is an anti-allergic agent with antiasthmatic, anti-inflammatory, and antifibrotic activity.
- Orally active Th2 cytokine inhibitor
- Inhibits IL-4 and IL-5 production
- Suppresses IgE synthesis
- Anti-allergic agent
- Antiasthmatic activity
- Anti-inflammatory activity
- Antifibrotic activity
Cayman Chemical Mifepristone Neurochemicals
An antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively); selective for these receptors over MR, ERα, and ERβ (Kis = 640, >200, and >750 nM, respectively); inhibits R5020-stimulated alkaline phosphatase activity as well as reporter transcription stimulated by either dexamethasone or R5020 in cell-based assays (IC50s = 7, 5.9, and 1.3 nM, respectively); inhibits R1881-stimulated reporter transcription in a concentration-dependent manner; inhibits growth of 4-OHT-resistant MCF-7 breast cancer cells in vitro at 10 µM; inhibits tumor growth in an SKOV3 ovarian cancer nude mouse xenograft model at 0.5 or 1 mg per day