Drug Standards
Medchemexpress LLC Abacavir | 136470-78-5 | 286.34 | 5 MG
Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. It can inhibit the replication of HIV and demonstrates anticancer activity in prostate cancer cell lines. Abacavir is also capable of trespassing the blood-brain-barrier and suppressing telomerase activity.
- Orally active and competitive nucleoside reverse transcriptase inhibitor
- Inhibits the replication of HIV
- Shows anticancer activity in prostate cancer cell lines
- Can trespass the blood-brain-barrier
- Suppresses telomerase activity
Medchemexpress LLC 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile | 1240948-72-4 | MFCD28404592 | 10g
Vonoprazan impurity 6 is an impurity of Vonoprazan (HY-100007)
Medchemexpress LLC (E)-N-(4-((3,4-difluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide | 2803478-55-7 | 5mg
Dacomitinib impurity 1 is an impurity of Dacomitinib (HY-13272)
Apexbio Technology LLC Pantoprazole 102625-70-7 10mM (in 1mL DMSO)
Pantoprazole is an inhibitor of H /K -ATPase frequently utilized in biomedical research to explore mechanisms related to gastric acid secretion and intracellular acidification Upon acid-activated conversion to its sulfenamide derivative pantoprazole irreversibly binds to cysteine residues (Cys813 and Cys822) in gastric parietal cell proton pumps thus suppressing proton transport and subsequent acid secretion Pantoprazole also impairs lysosomal acidification with an IC50 value of approximately 194 M Its reported antimicrobial activity against Helicobacter pylori expands its experimental application making pantoprazole suitable in studies involving gastric physiology proton pump enzymology lysosomal function and bacterial pathogenesis
TARGETMOL CHEMICALS INC CLEVUDINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly clevudine is phosphorylated to its active metabolites clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA) therefore the patient is less likely to have a relapse after treatment is discontinued. purity: 99%
Apexbio Technology LLC Folic acid 59-30-3 5g
Folic acid (CAS 59-30-3) is a water-soluble B9 vitamin structurally derived from Spinacia oleracea It functions as a cofactor in one-carbon transfer reactions facilitating nucleotide synthesis and methylation processes essential for DNA replication and cellular division Due to its involvement in folate metabolism folic acid is frequently utilized in studies of cell proliferation gene expression regulation and metabolic disorders For optimal stability folic acid should be stored in a sealed container under cool dry conditions
Medchemexpress LLC Fostamatinib disodium hexahydrate | 914295-16-2 | 99.5% | 50 MG
Fostamatinib disodium hexahydrate is an oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor, also inhibiting Lyn and Lck. This product is for research use only.
- Oral proagent of R406
- Orally available
- Competitive Syk/FLT3 inhibitor
- Inhibits Lyn and Lck
- For research use only
Medchemexpress LLC Carbidopa | 28860-95-9 | 99.8% | 10 MM 1 ML
Carbidopa, also known as (S)-(-)-Carbidopa, is a peripheral decarboxylase inhibitor primarily used for research related to Parkinson's disease. It also functions as a selective aryl hydrocarbon receptor (AhR) modulator and has been shown to inhibit pancreatic cancer cell and tumor growth.
- Acts as a peripheral decarboxylase inhibitor
- Functions as a selective aryl hydrocarbon receptor (AhR) modulator
- Demonstrates anticancer activity by inhibiting pancreatic cancer cell and tumor growth
- High purity of 99.84% ensures reliability for research applications
- Comprehensive documentation available, including Data Sheet, COA, SDS, HNMR, RP-HPLC, and Handling Instructions
- Detailed solubility information provided for in vitro and in vivo applications, with protocols for preparing clear stock and working solutions
- Intended for research use only
Apexbio Technology LLC Glipizide 29094-61-9 10mM (in 1mL DMSO)
Glipizide (CAS 29094-61-9) is a small molecule that acts by inhibiting ATP-sensitive potassium channels in pancreatic cells leading to membrane depolarization and subsequent stimulation of insulin secretion Additionally it modulates ATP-dependent K channels in GABAergic neurons within the brain Glipizide is widely used in research to investigate pancreatic cell physiology insulin release mechanisms and the role of KATP channels in neuroendocrine regulation
Echelon Biosciences Research Labs Ins(1,3,4,6)P4 100 ug
Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,3,4,6-tetrakissphosphate (Ins(1,3,4,6)P4) is an intermediate in the synthesis of InsP6 (phytic acid), being phosphorylated by Ins(1,3,4,6)P4 5-kinase to Ins(1,3,4,5,6)P5. It is formed from Ins(1,3,4)P3 by Ins(1,3,4)P3 5,6-kinase. This item is non returnable
Cayman Chemical FamcIclovIr 100mg
An orally bioavailable prodrug form of penciclovir; oxidized in vitro by human, guinea pig, and rat liver aldehyde oxidase; in rats the peak concentrations of penciclovir in plasma (mean 3.5 μg/ml) occur in 0.5 hours (40 mg/kg); in dogs the peak concentrations of penciclovir in plasma (mean 4.4 μg/ml) occur in 3 hours (25 mg/kg)
Cayman Chemical DIclofenac AcylDGlucuronI 10mg
An intermediate in the synthesis of diclofenac acyl-β-D-glucuronide
Cayman Chemical OxIbendazole 250mg
A benzimidazole anthelmintic; inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM, respectively); reduces fecal worm egg counts in dogs and cats by greater than 90% for the nematodes T. canis, T. vulpis, A. caninum, and T. leonine at 15 mg/kg in combination with niclosamide; reduces fecal egg counts of strongyles in horses at 10 mg/kg per day
Medchemexpress LLC 3-(4-bromo-7-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 2438239-34-8 | ≥97.0% | 341.13 g/mol | C13H10BrFN2O3 | 50 MG
Lenalidomide-4-Br-7-fluoro is a synthetic analog of lenalidomide bearing bromine and fluorine substituents on the benzyl ring. Supplied as a solid research-use compound, it is used in chemical biology and medicinal chemistry to probe cereblon engagement and structure-activity relationships. The material is offered at high purity for analytical and biological studies.
- Derivative of lenalidomide with bromo and fluoro substituents.
- Used to study cereblon (CRBN) ligand interactions and degradation pathways.
- Provided as a solid powder suitable for small-scale assays and synthesis.
- High purity appropriate for analytical and biological experiments.
- Available in small pack sizes for research screening workflows.
Medchemexpress LLC Methylprednisolone succinate | 2921-57-5 | 99.7% | 100 MG
Methylprednisolone succinate is a prodrug of Methylprednisolone and a glucocorticoid with immunosuppressant and anti-inflammatory activity. It binds to cytosolic glucocorticoid receptors, translocates to nuclei, and modulates target gene transcription. It alters Bax, Bcl-2, occludin, and ZO-1 expression, attenuates TLR4/NF-κB signaling, and suppresses proinflammatory cytokine production and immune cell activation. This product is for research use only.
- Suppresses inflammatory responses
- Attenuates blood-brain barrier disruption
- Reduces neuronal apoptosis
- Improves collateral blood flow into infarcted areas
- Enhances metabolic response of ischemic myocardium
- Modulates target gene transcription
- Used for research on various inflammatory conditions and injuries