Drug Standards
Cayman Chemical HarpagosIde 10mg
An iridoid glycoside with diverse biological activities; inhibits LPS-induced increases in COX-2 and NO levels, as well as TNF mRNA expression in HepG2 cells from 50-200 µM; reduces synovial inflammation, joint destruction, and bone erosion in a mouse model of collagen-induced arthritis at 10 mg/kg; decreases substantia nigra pars compacta neuronal cell death and increases time spent on the rod in a rotarod test in a mouse model of MPTP-induced Parkinson’s disease
Medchemexpress LLC Hydroxy Itraconazole | 112559-91-8 | 99.8% | 100 UG
Hydroxy Itraconazole is the analytical standard of Hydroxy Itraconazole, intended for research and analytical applications.
- CAS number: 112559-91-8
- Molecular weight: 721.63
- Molecular formula: C35H38Cl2N8O5
- Purity (LCMS): 99.80%
- Appearance: White to off-white solid
- Storage: 4°C, protect from light (solid); -80°C, 6 months; -20°C, 1 month (in solvent)
- Application: Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC Rebamipide impurity 13 | 4876-17-9 | MFCD22194962 | >=98.0% | 193.63 | C10H8ClNO | 100 MG
Rebamipide impurity 13 is a defined impurity of the gastroprotective agent rebamipide supplied for research and analytical use. It is intended as a reference standard, impurity profiling aid, or synthetic intermediate for drug-development and analytical chemistry. Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Defined chemical impurity for analytical standards.
- Suitable for impurity profiling and method development.
- Useful as a synthetic intermediate for organic synthesis.
- Molecular formula C10H8ClNO; molecular weight 193.63.
- Store as powder or in solvent per recommended conditions.
Medchemexpress LLC Alverine citrate | 5560-59-8 | 99.5% | 10 MM 1 ML
Alverine citrate is a 5-HT1A receptor antagonist with an IC50 of 101 nM, primarily used for research and analytical applications. It acts directly on gut muscles, causing relaxation, and is used in studies of functional gastrointestinal disorders. This compound shows high affinity for 5-HT1A receptors and weak affinity for 5-HT3 and 5-HT4 subtypes.
- 5-HT1A receptor antagonist
- IC50 of 101 nM
- Used for research and analytical applications
- Relaxes gut muscles
- High affinity for 5-HT1A receptors
- Molecular formula: C26H35NO7
- Molecular weight: 473.56
- Appearance: White to off-white solid
Medchemexpress LLC Ranitidine | 66357-35-5 | MFCD00081180 | 99.9% | 5 MG
Ranitidine is a potent, selective, and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It antagonizes histamine-induced increases in guinea-pig isolated rat atrium and histamine-induced relaxations of the rat isolated uterine horn. Studies also show it inhibits breast tumor development and spread in mice.
- Potent and selective histamine H2-receptor antagonist
- Orally active
- Inhibits gastric secretion
- Antagonizes histamine-induced increases in guinea-pig isolated rat atrium
- Antagonizes histamine-induced relaxations of rat isolated uterine horn
- Inhibits breast tumor development and spread in mice
- Reduces CD11b+Ly6Chi cells in spleen and bone marrow
- Inhibits lung metastasis
- Inhibits primary tumor growth
- Increases latency of breast tumorigenesis
- Reduces number of tumors
Apexbio Technology LLC Carmofur 61422-45-5 10mM (in 1mL DMSO)
Carmofur is a fluorouracil derivative that functions as an anticancer agent by inhibiting thymidylate synthetase thereby interfering with DNA synthesis and cell proliferation As a cytostatic compound it is used primarily in oncology research for in vitro studies investigating tumor growth inhibition pathways Research demonstrates Carmofur s cytotoxic activity in various cancer cell lines with reported IC50 values typically ranging from approximately 5 to 50 M depending on the cell type and culture conditions It is commonly applied in cellular assays including viability assays apoptosis pathway analysis and mechanistic studies of fluorouracil resistance providing insight into targeted pharmacological interventions and chemotherapeutic response mechanisms
Medchemexpress LLC Diclofenac ethyl ester | 15307-77-4 | 99.3% | 100 MG
Diclofenac ethyl ester is a prodrug of Diclofenac, designed for enhanced delivery. It is encapsulated in polymer micelles in vitro and released with prolonged circulation time and reduced drug concentrations in the heart and kidneys in vivo.
- Prodrug of Diclofenac
- Encapsulated in polymer micelles
- Prolonged circulation time
- Reduced drug concentrations in heart and kidneys
Medchemexpress LLC Flunixin meglumine | 42461-84-7 | 99.5% | 100 MG
Flunixin meglumine (Standard) is an analytical standard and a cyclooxygenase (COX) inhibitor. It demonstrates anti-inflammatory effects, making it suitable for various research and analytical applications.
- Analytical standard for research
- Acts as a cyclooxygenase (COX) inhibitor
- Exhibits anti-inflammatory effects
- Used as a reference standard in HPLC, GC, and MS experiments
Medchemexpress LLC Pinaverium impurity 1 | 54370-00-2 | MFCD02093896 | 247.09 | C9H11BrO3 | 100 MG
Pinaverium impurity 1 is a chemical impurity related to pinaverium, supplied for research and analytical use. It is provided as a drug intermediate and characterized by its molecular composition and identifiers.
- Used as an impurity reference or intermediate in analytical and synthetic work.
- Chemical formula C9H11BrO3, molecular weight 247.09.
- CAS number 54370-00-2 for unambiguous identification.
- Intended for research use only; not for human or animal therapeutic use.
- Storage and handling instructions provided on the certificate of analysis.
Medchemexpress LLC Alverine citrate | 5560-59-8 | 99.49% | 5 G
Alverine citrate is a 5-HT1A receptor antagonist with an IC50 of 101 nM. It is a drug used for functional gastrointestinal disorders and acts directly on the muscle in the gut, causing it to relax. It suppresses the effect of 5-HTP, but not that of 8-OH-DPAT. This compound is suitable for various laboratory applications.
- Acts as a 5-HT1A receptor antagonist
- Used for functional gastrointestinal disorders
- Relaxes gut muscles directly
- Suppresses the effect of 5-HTP
- Has a high affinity for 5-HT1A receptors
Medchemexpress LLC Proguanil hydrochloride | 637-32-1 | 99.2% | 5 MG
Proguanil hydrochloride is an antimalarial proagent that is metabolized to its active form, Cycloguanil. It functions as a dihydrofolate reductase (DHFR) inhibitor. While Proguanil itself has weak antimalarial activity, its effectiveness is primarily attributed to Cycloguanil. The combination of Atovaquone and Proguanil shows synergistic activity in vitro, effective against gametocytes and pre-erythrocytic (hepatic) stages of malaria parasites. Additionally, Proguanil, its metabolite 4-chlorophenyl-1-biguanide (CPB), and Cycloguanil reversibly inhibit 5-HT3 receptor responses.
- Metabolized to active form, Cycloguanil
- Functions as a dihydrofolate reductase (DHFR) inhibitor
- Exhibits weak antimalarial activity in vitro, enhanced by Cycloguanil
- Synergistic with Atovaquone against malaria parasites
- Inhibits gametocytes and pre-erythrocytic stages
- Reversibly inhibits 5-HT3 receptor responses
Sigma Aldrich Fine Chemicals Biosciences Thiotepa British Pharmacopoeia (BP) Reference Standard | 52-24-4 | MFCD00145452 |
Thiotepa British Pharmacopoeia (BP) Reference Standard | Mol Wt: 189.22 | 52-24-4 | MFCD00145452 |
Sigma Aldrich Fine Chemicals Biosciences Sodium cholate hydrate PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. | 206986-87-0 | MFCD00150749 | 100G
Sodium cholate hydrate PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. | 206986-87-0 | MFCD00150749 | 100G
Medchemexpress LLC Voriconazole | 188416-29-7 | MFCD00905717 | 99.1% | 349.31 g/mol | C16H14F3N5O | 100 MG
(±)-Voriconazole is the racemic form of the triazole antifungal voriconazole supplied as a chemically characterized research standard. It is intended for laboratory and analytical applications where a defined reference material is required. The material is provided with batch-specific documentation and analytical data to support quality and traceability.
- Racemic form of voriconazole suitable as a reference standard.
- High purity for analytical and research use.
- Chemical formula C16H14F3N5O and molecular weight 349.31 g/mol.
- Available in 100 mg laboratory pack sizes.
- Supplied with certificate of analysis for batch-specific data.