Drug Standards
Medchemexpress LLC Flutrimazole | 119006-77-8 | 99.3% | 50 MG
Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. It shows scarce transdermal penetration and is advantageous in the research of topical fungal infections with an inflammatory component.
- Imidazole antifungal
- Dual anti-inflammatory and antifungal activity
- Scarce transdermal penetration
- Suitable for research into topical fungal infections with an inflammatory component
Apexbio Technology LLC Itraconazole(Synonyms: Sporanox, Orungal, R51211, Lozanoc, Triasporin, Fungitraxx, Onmel, Itranox, Sporal, Itrizole, Candistat), 10mM (in 1mL DMSO), CAS: 84625-61-6.
Itraconazole (CAS 84625-61-6) is a triazole-based antifungal compound that functions primarily by inhibiting cytochrome P450 enzymes particularly CYP3A4 As both a substrate and inhibitor of CYP3A4 itraconazole undergoes oxidative metabolism into hydroxylated keto- and N-dealkylated derivatives all with demonstrated inhibitory activities comparable or superior to the parent compound In addition to antifungal effects itraconazole inhibits the hedgehog signaling pathway and angiogenesis Due to its affinity for mammalian CYP-P450 enzymes itraconazole is frequently employed in drug interaction studies assessing CYP3A-mediated metabolism
Cayman Chemical SynthetIc GItoxIn 10mg
A cardiac glycoside with cardiotonic and antiarrhythmic activities; inhibits Na+/K+-ATPase in an isoform-specific biphasic manner with IC50 values of 0.298 and 410 µM for the high- and low affinity human erythrocyte isoenzymes, respectively, and 1.18 and 28.5 µM for the high- and low affinity porcine cerebral cortex isoenzymes, respectively; increases contractility and rhythmicity in isolated guinea pig heart in a concentration-dependent manner; a degradation product of digoxin
eMolecules 404-86-4 | Capsaicin, natural | Chem-Impex305.418 | C18H27NO3 | 100.000 | COc1cc(CNC(=O)CCCCC=CC(C)C)ccc1O | 1g | 112756073
Capsaicin, natural | Chem-Impex | 404-86-4305.418 | C18H27NO3 | 100.000 | COc1cc(CNC(=O)CCCCC=CC(C)C)ccc1O | 1g | 112756073
Apexbio Technology LLC Betamethasone 378-44-9 10mM (in 1mL DMSO)
Betamethasone is a synthetic corticosteroid functioning primarily as a glucocorticoid receptor agonist Mechanistically it modulates gene expression through binding glucocorticoid receptors regulating transcription factors and subsequently affecting protein synthesis Betamethasone influences inflammatory pathways by inhibiting key enzyme expressions such as phospholipase A2 cyclooxygenase-2 (COX-2) and nitric oxide synthase (NOS) resulting in decreased synthesis of inflammatory mediators like prostaglandins leukotrienes and nitric oxide Additionally it has been reported to suppress keratinocyte proliferation Due to its glucocorticoid-modulating properties and anti-inflammatory effects betamethasone is commonly employed in biomedical research involving inflammatory signaling pathways dermatological models and gene expression studies
U.S. Pharmacopeia Ketorolac Related Compound C, 113502-52-6, MFCD22048820, 20 mg
Empirical Formula (Hill Notation): C14H11NO2, Molecular Weight: 225.24, Synonym: 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one.
Apexbio Technology LLC (-)-epicatechin gallate 1257-08-5 10mM (in 1mL DMSO)
(-)-Epicatechin gallate (ECG) is a catechin compound abundant in green tea displaying bioactivity to modulate cell proliferation apoptosis and gene expression pathways In colon HCT-116 cells ECG induces apoptosis through activating transcription factor 3 (ATF3) regulated via activation of early growth response protein 1 (EGR-1) In these cancer cells ECG upregulates apoptotic factor NAG-1 and increases caspase-3 activity at concentrations around 150 M ECG s cytotoxic potency differs among cell types with an NR50 (midpoint cytotoxic concentration) of approximately 67 M in HSC-2 oral cancer cells while normal human fibroblast HGF-2 cells show greater resistance with an NR50 near 100 M ECG metabolites identified in rat urine include various O-methylated derivatives useful as biomarkers for metabolism studies ECG serves as a research tool for oncology mechanisms and apoptosis signaling pathways
Sigma Aldrich Fine Chemicals Biosciences Enalaprilat dihydrate >=98% (HPLC) | 84680-54-6 | MFCD00941393 | 5MG
Enalaprilat dihydrate >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 384.42 | 84680-54-6 | MFCD00941393 | 5MG
Medchemexpress LLC Flunixin (meglumine) | 42461-84-7 | 99.65% | 1 ML
Flunixin meglumine is a cyclooxygenase (COX) inhibitor exhibiting anti-inflammatory effects. It inhibits lipopolysaccharide-induced inducible nitric oxide synthase (iNOS) activity and nuclear factor kappa B (NfκB) activation in RAW 264.7 murine macrophages. In vivo, it inhibits carrageenan-induced exudate PGE2 and serum TXB2 generation.
Medchemexpress LLC Metformin-d6 hydrochloride | 1185166-01-1 | MFCD06658649 | 98.0% | 171.66 g/mol | C4H6D6ClN5 | 5 MG
Metformin-d6 hydrochloride is a deuterium-labeled metformin hydrochloride supplied as a research-grade analytical standard for use as an internal standard in quantitative LC-MS/GC-MS and tracer studies. For laboratory research use only; not for human consumption.
- Deuterium-labeled analogue suitable as an internal standard for mass spectrometry.
- High chemical purity: 98.0% as reported by supplier certificate of analysis.
- High isotopic enrichment (99.8%), supporting accurate quantification and tracing.
- Available as a solid in small analytical quantities for method development and validation.
- Compatible with common analytical workflows including LC-MS and GC-MS.
Medchemexpress LLC Hydrochlorothiazide (standard) | 58-93-5 | 99.6% | 50 MG
Hydrochlorothiazide (Standard) is the analytical standard of Hydrochlorothiazide, intended for research and analytical applications. It is an orally active diuretic agent of the thiazide class that inhibits the transforming TGF-β/Smad signaling pathway. It also has direct vascular relaxant effects by opening the calcium-activated potassium (KCA) channel, improving cardiac function, reducing fibrosis, and exhibiting an antihypertensive effect. This compound is an analytical standard supplied for assay.
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Idelalisib-d5 | 1830330-31-8 | 98.4% | 1 MG
Idelalisib-d5 is a deuterium-labeled Idelalisib. It is a highly selective and orally bioavailable p110δ inhibitor.
- Serves as a tracer
- Functions as an internal standard for quantitative analysis
- Compatible with NMR, GC-MS, or LC-MS techniques
Medchemexpress LLC Triprolidine hydrochloride monohydrate | 6138-79-0 | MFCD00150574 | 99.9% | 332.87 | C19H25ClN2O | 10 MG
Triprolidine hydrochloride monohydrate is a first-generation histamine H1 receptor antagonist provided as a research reagent for in vitro and related laboratory studies. It is supplied as a solid monohydrate for solution preparation and analytical work.
- First-generation H1 histamine antagonist used for pharmacological research.
- Provided as a solid monohydrate, white to off-white in appearance.
- Molecular formula C19H25ClN2O and molecular weight 332.87 g/mol.
- Available in small measured packs suitable for laboratory assays and preparative work.
- Typical quality assurance includes batch COA with purity determined by LCMS.
Med Vet International Dynarex Suction Connection Tubing w/ Male Connector, Non-Conductive,, 3/16" x 12' Tube, 20/Case
Dynarex Resp-O2™ Suction Connecting Tubing is designed to provide secure connections to portable and in-wall suction sources. This durable tubing offers the ultimate in versatility—featuring a female connector at each end and an optional rigid male (straw) adapter for attaching additional tubes. The sterile tubing is disposable and designed for single use to promote optimal hygiene. This high-quality tubing is disposable and designed for single use to promote optimal hygiene. Dynarex Resp-O2™ Suction Connecting Tubing is designed to provide secure connections to both portable and in-wall suction sources. This non-conductive Tubing features female connectors on both ends and includes an optional male (straw) adapter for additional attachments.