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Filtered Search Results
Apexbio Technology LLC Asenapine 85650-56-2 1g
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Asenapine (CAS 85650-56-2) is a small-molecule psychotropic agent characterized by high-affinity antagonism at multiple neurotransmitter receptors including several serotonin (5-HT) dopamine noradrenaline and histamine receptor subtypes (with reported pK sub i /sub values in the high nanomolar to sub-nanomolar range such as 8 60 8 40 10 15 9 75 and 10 46) This broad receptor antagonism profile underlies its capacity to modulate neurotransmission in various central nervous system pathways Asenapine is widely employed in biomedical research to investigate the pharmacological basis of antipsychotic activity and to study the functional roles of monoaminergic and histaminergic signaling in psychiatric and neuropharmacological models
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Inorganic Ventures 1000µg/mL CARBONATE 125mL
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Matrix: Water (H2O), Starting Material: Na2CO3, Analyte: CO3-2 1000 ug/mL.
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Apexbio Technology LLC L-Thyroxine 51-48-9 1g
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L-Thyroxine (51-48-9) is a thyroid hormone analog that regulates cellular metabolism via thyroid hormone receptor activation It modulates gene expression after peripheral conversion to its active form triiodothyronine (T3) thereby influencing metabolic pathways including lipid catabolism and cholesterol metabolism L-Thyroxine exerts its biological activity primarily through receptor-mediated transcriptional regulation Based on these pharmacological properties L-Thyroxine holds research potential in thyroid function studies and metabolic regulation investigations particularly in the context of hypothyroidism and altered thyroid hormone signaling
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Apexbio Technology LLC Thiabendazole 148-79-8 1g
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Thiabendazole (CAS 148-79-8) is a small-molecule inhibitor targeting microtubule assembly It is designed to disrupt microtubule formation thereby altering fungal cell cycle progression Thiabendazole exerts its biological activity primarily through inhibition of microtubule assembly In in vitro studies thiabendazole demonstrates inhibition of CYP1A2 enzyme activity with an IC50 value ranging from 0 5 to 1 M in enzymatic interaction assays Based on these pharmacological properties thiabendazole holds research potential in metabolic enzyme studies and environmental toxicology investigations
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Apexbio Technology LLC Calcium Gluceptate 17140-60-2 1g
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Calcium Gluceptate (CAS 17140-60-2) is a calcium salt frequently utilized in biomedical research to modulate extracellular calcium concentrations and investigate calcium-dependent physiological processes including signal transduction muscle contraction and enzymatic functions By supplying bioavailable calcium ions it enables controlled studies of cellular calcium influx and related pathways Calcium Gluceptate is available in diverse purity grades suitable for a range of experimental protocols and is applicable in pharmacological assays tissue culture supplementation and studies of calcium homeostasis
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Apexbio Technology LLC DTNB 69-78-3 1g
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DTNB (69-78-3) is a biochemical reagent that reacts specifically with free sulfhydryl (-SH) groups It is utilized to quantitatively detect thiol groups in biological samples DTNB exerts its activity by undergoing disulfide bond cleavage upon interaction with free thiols leading to the formation of a colored derivative 5-thio-2-nitrobenzoate (TNB) which is measurable by spectrophotometry at 412 nm Based on these properties DTNB is widely applied in the quantification of reduced glutathione (GSH) and assessment of thiol levels in tissues blood and cultured cells enabling studies of oxidative stress redox state and thiol-reactive drug screening
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Apexbio Technology LLC Cefdinir 91832-40-5 1g
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Cefdinir (91832-40-5) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby obstructing the final transpeptidation step of peptidoglycan formation Cefdinir exerts its biological activity primarily through PBP binding-mediated inhibition of cell wall biosynthesis In microbiological assays Cefdinir demonstrates antibacterial inhibition with reported IC50 values ranging from approximately 0 5 to 4 g/mL against susceptible bacteria Based on these pharmacological properties Cefdinir holds research potential in antibacterial susceptibility testing determination of minimum inhibitory concentrations (MIC) and investigation of antibiotic resistance mechanisms
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Apexbio Technology LLC TBHQ 1948-33-0 1g
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Tert-butylhydroquinone (TBHQ CAS 1948-33-0) is a synthetic aromatic compound structurally characterized by a phenylpropanoid framework TBHQ functions primarily as an antioxidant where it inhibits the peroxidation of lipids by scavenging free radicals and stabilizing cell membranes Beyond its established role in food preservation TBHQ is widely utilized in biomedical research to investigate oxidative stress responses and cellular defense mechanisms Its modulatory effects on signaling pathways such as Nrf2-mediated transcription underscore its value in studies related to redox biology and cytoprotection
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Apexbio Technology LLC Chenodeoxycholic Acid 474-25-9 1g
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Chenodeoxycholic Acid is a small-molecule agonist targeting the farnesoid X receptor (FXR) It is designed to selectively activate FXR thereby regulating critical signaling pathways involved in bile acid homeostasis lipid metabolism and cholesterol regulation Chenodeoxycholic Acid exerts its biological activity primarily through FXR-dependent modulation of transcriptional pathways Based on these pharmacological properties Chenodeoxycholic Acid holds research potential in the investigation of hepatic metabolism mechanisms cholesterol balance metabolic disorders and FXR-mediated gene expression in various physiological and pathological conditions
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Apexbio Technology LLC Mepiroxol 6968-72-5 1g
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Mepiroxol is a small-molecule compound characterized by its ability to form specific interactions with target proteins It engages in salt bridge interactions with arginine residues (such as Arg-153 and Arg-74) and participates in hydrogen bonding via its hydroxyl group with protein residues like Asp-50 and Gly-96 supporting enhanced binding affinity Researchers utilize Mepiroxol for investigations into protein-ligand interaction mechanisms aiding structural biology analyses and guiding drug-design efforts
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Apexbio Technology LLC Oxipurinol 2465-59-0 1g
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Oxipurinol (CAS 2465-59-0) is a small molecule inhibitor of xanthine oxidoreductase (XO) an enzyme integral to purine metabolism As the principal active metabolite of allopurinol oxipurinol functions as a noncompetitive XO inhibitor contributing significantly to the pharmacological effects observed with allopurinol therapy In vitro studies indicate that both allopurinol and oxipurinol demonstrate XO inhibition and exhibit free radical scavenging properties with evidence of cardioprotective effects independent of XO activity In vivo oxipurinol administration has been shown to reduce vascular free radical production in hypercholesterolemic animal models Its pharmacokinetic profile is characterized by predominant renal clearance Oxipurinol is widely utilized in research exploring oxidative stress cardiovascular physiology and disorders of purine metabolism
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Apexbio Technology LLC Pyriproxyfen 95737-68-1 1g
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Pyriproxyfen (CAS 95737-68-1) is a small-molecule inhibitor targeting insect juvenile hormone receptors It is designed to interfere with hormone-mediated developmental signaling thereby disrupting endocrine-regulated metamorphosis in insect larvae Pyriproxyfen exerts its biological activity primarily through binding to juvenile hormone receptors impeding physiological maturation and reproduction cycles in target arthropod populations In laboratory experiments pyriproxyfen demonstrates inhibitory activity with IC50 values ranging from approximately 0 1 to 10 M depending on insect species and experimental conditions Based on these pharmacological properties pyriproxyfen holds research potential in agricultural pest management and public health applications involving vector-borne diseases transmitted by arthropods
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Waters Corp PIC Reagent B5
Paired -Ion Chromatography (PIC Reagents) provide an easy solution for analyzing samples containing ionic species. These reagents allow ionic compounds to be separated by reverse-phase chromatography, saving time by allowing simultaneous assay of acids, bases, amphoteric and neutral compounds. PIC B5 is a 5 vials/pkg workable solution in UV range in mobile phase of 240+ nm.
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Apexbio Technology LLC Diethylstilbestrol 56-53-1 1g
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Diethylstilbestrol (56-53-1) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase type 2 (HSD11B2) and interacting with estrogen receptors It is designed to modulate hormonal signaling and cellular steroid metabolism thereby regulating processes such as apoptosis and autophagy Diethylstilbestrol exerts its biological activity primarily through the inhibition of HSD11B2 and modulation of estrogen receptor-mediated signaling In cell-based studies Diethylstilbestrol induces oxidative DNA damage and triggers apoptotic responses in spermatogonial stem cells as well as promotes autophagy in thymic cells Based on these pharmacological properties Diethylstilbestrol holds research potential in exploring estrogen receptor-mediated signaling hormone-regulated molecular events apoptosis pathways and autophagy mechanisms in vitro
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Inorganic Ventures 1000µg/mL BARIUM 125mL
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Inorganic Ventures' 1000 ppm (µg/mL) Barium for IC is a 125mL certified reference material set in a nitric acid matrix for stability. This barium standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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