Acetylides
Medchemexpress LLC Propargyl-PEG4-CH2COOH | 1429934-37-1 | ≥97.0% | 290.31 | 1 G
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This compound is a colorless to light yellow liquid.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules
- Appearance: colorless to light yellow liquid
- Molecular formula: C13H22O7
Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | 302.36 | 250 MG
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent containing an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
- Utilizes two different ligands connected by a linker; one ligand for an E3 ubiquitin ligase and another for the target protein
- Employs the intracellular ubiquitin-proteasome system to selectively degrade target proteins
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 1 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 30 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 47.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-peg8-oh | 1351556-81-4 | 250 MG
Propargyl-PEG8-OH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups.
- Utilized in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an alkyne group for CuAAC reactions
- Leverages the intracellular ubiquitin-proteasome system
Medchemexpress LLC Propargyl-PEG7-acid | 2093154-00-6 | ≥98.0% | 1 G
Propargyl-PEG7-acid is a PEG-based PROTAC linker and a cleavable ADC linker, making it valuable for synthesizing PROTACs and antibody-drug conjugates. It also functions as a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.
- Used in the synthesis of PROTACs
- Cleavable ADC linker
- Utilized in the synthesis of antibody-drug conjugates (ADCs)
- Functions as a click chemistry reagent
- Contains an Alkyne group for copper-catalyzed azide-alkyne cycloaddition
Medchemexpress LLC Propargyl-peg1-acid | 55683-37-9 | 97.0% | 250 MG
Propargyl-PEG1-acid is a PEG-based PROTAC linker. It is utilized in the synthesis of BTK-CRBN PROTACs and functions as a click chemistry reagent. This product incorporates an Alkyne group which can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Utilized in the synthesis of BTK-CRBN PROTACs
- Functions as a click chemistry reagent
- Incorporates an Alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Medchemexpress LLC Propargyl-PEG3-bromide | 203740-63-0 | 97.7% | 251.12 | 5 G
Propargyl-PEG3-bromide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, containing an Alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker for synthesizing PROTACs.
- Functions as a click chemistry reagent.
- Contains an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc).
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system.
Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | 302.36 | 25 MG
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Used in the synthesis of PROTACs
- For research use only
Medchemexpress LLC Propargyl-PEG3-methane | 89635-82-5 | 98.0% | 202.25 | 25 G
Propargyl-PEG3-methane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups. For research use only. Not sold to patients.
- Click chemistry reagent
- Alkynes
- PROTAC synthesis
- PROTAC linkers
- Used in cancer research
- Applied in cancer targeted therapy
Medchemexpress LLC Propargyl-PEG1-bromide | 18668-74-1 | MFCD00099299 | 98.0% | 163.01 g/mol | C5H7BrO | 100 MG
Propargyl-PEG1-bromide is a short polyethylene glycol (PEG) derivative bearing a terminal propargyl (alkyne) group and a bromide leaving group. It is used as a reactive linker in synthetic and chemical biology workflows where a minimal PEG spacer and an alkyne handle enable conjugation and further functionalization. Typical applications include click chemistry, bioconjugation, and assembly of drug-delivery constructs.
- Contains a terminal propargyl (alkyne) functional group for click reactions.
- Contains a bromide leaving group for nucleophilic substitution.
- One-unit PEG spacer provides improved solubility with low steric bulk.
- Enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Suitable for linker synthesis, bioconjugation, and drug-delivery research.
- Small molecular weight and compact linker length for precision conjugation.
eMolecules 927-58-2 | 4-Bromobutyryl chloride | Ambeed | MFCD00000753 | 185.450 | C4H6BrClO | 95.000 | ClC(=O)CCCBr | 1g | 570996278
4-Bromobutyryl chloride | Ambeed | 927-58-2 | MFCD00000753 | 185.450 | C4H6BrClO | 95.000 | ClC(=O)CCCBr | 1g | 570996278
eMolecules 92136-39-5 | Boc-Propargylamine | Ambeed | MFCD07367245 | 155.197 | C8H13NO2 | 99.000 | CC(C)(C)OC(=O)NCC#C | 1g | 552613515
Boc-Propargylamine | Ambeed | 92136-39-5 | MFCD07367245 | 155.197 | C8H13NO2 | 99.000 | CC(C)(C)OC(=O)NCC#C | 1g | 552613515