Acetylides
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 5 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 100 mL Glass (Septum)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 100.4 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-PEG2-CH2COOH | 944561-46-0 | ≥95.0% | 202.20 | 250 MG
Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- Used in the synthesis of PROTACs.
- Contains an Alkyne group.
- Can undergo copper-catalyzed azide-alkyne cycloaddition with Azide groups.
Medchemexpress LLC Propargyl-PEG1-NHS ester | 1174157-65-3 | 99.7% | 225.20 g/mol | C10H11NO5 | 250 MG
A non-cleavable one-unit polyethylene glycol (PEG) linker supplied as an NHS ester with a terminal propargyl (alkyne) group. Designed for click chemistry (CuAAC) and antibody-agent conjugation, it is provided as a colorless to light-yellow solid-liquid mixture with high purity and recommended cold storage.
- One-unit PEG linker for minimal spacer length.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- NHS ester allows efficient coupling to primary amines.
- High purity suitable for conjugation chemistry.
- Cold storage recommended for long-term stability.
eMolecules 1391002-18-8 | 3-Fluoro-5-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | MFCD18783233 | 267.180 | C10H9F4NO3 | 95.000 | NC(Cc1cc(F)cc(OC(F)(F)F)c1)C(O)=O | 1g | 562455577
3-Fluoro-5-(trifluoromethoxy)-DL-phenylalanine | Apollo Scientific | 1391002-18-8 | MFCD18783233 | 267.180 | C10H9F4NO3 | 95.000 | NC(Cc1cc(F)cc(OC(F)(F)F)c1)C(O)=O | 1g | 562455577
Medchemexpress LLC D(+)-Raffinose pentahydrate | 17629-30-0 | 594.51 | 5 G
D(+)-Raffinose pentahydrate is an orally active inhibitor of LecA (Kd = 32 μM) and GtfC. It functions by reducing cyclic diguanylate (c-di-GMP) through increased activity of a c-di-GMP specific phosphodiesterase and interferes with GTF function. This compound decreases IL-4 and IL-5 mRNA, exhibits biofilm-inhibitory activity against *Pseudomonas aeruginosa* and *Streptococcus mutans*, and inhibits allergic airway eosinophilia. It is intended for research use only and not for sale to patients.
- Orally active inhibitor of LecA and GtfC
- Reduces cyclic diguanylate (c-di-GMP)
- Interferes with GTF function
- Decreases IL-4 and IL-5 mRNA
- Exhibits biofilm-inhibitory activity against *Pseudomonas aeruginosa* and *Streptococcus mutans*
- Inhibits allergic airway eosinophilia
Medchemexpress LLC Propargyl-PEG1-SS-PEG1-t-butyl ester | 1807518-78-0 | MFCD28505559 | >98.0% | 320.47 g/mol | C14H24O4S2 | 10 MG
Propargyl-PEG1-SS-PEG1-t-butyl ester is a cleavable PEG-based linker containing terminal propargyl (alkyne) groups and a disulfide bond. It is used in bioconjugation workflows such as antibody-drug conjugate and PROTAC synthesis, and as a click-chemistry handle for azide-alkyne cycloaddition.
- Cleavable disulfide linkage allows intracellular reduction and payload release.
- Terminal propargyl groups enable copper-catalyzed and strain-promoted click reactions.
- High purity (>98.0%) suitable for synthetic chemistry applications.
- Molecular weight 320.47 g/mol and formula C14H24O4S2.
- Available in small research quantities (5 mg, 10 mg, 25 mg) for lab-scale synthesis.
eMolecules 106-96-7 | Propargyl bromide (80% wt.in toluene) contains 0.3% magnesium oxide as stabilizer | Oakwood Chemical211.102 | C10H11Br | 0.000 | BrCC#C.Cc1ccccc1 | 5g | 870167070
Propargyl bromide (80% wt.in toluene) contains 0.3% magnesium oxide as stabilizer | Oakwood Chemical | 106-96-7211.102 | C10H11Br | 0.000 | BrCC#C.Cc1ccccc1 | 5g | 870167070
Medchemexpress LLC Arecaidine propargyl ester hydrobromide | 116511-28-5 | MFCD00078566 | 99.5% | C10H14BrNO2 | 10MG
Arecaidine propargyl ester hydrobromide is a small-molecule M2 muscarinic acetylcholine receptor agonist supplied as the hydrobromide salt. It has been reported to modulate M2 receptor activity and to inhibit tumor cell proliferation in vitro. The compound is provided as a white to off-white solid for laboratory research applications and is characterized by a high-purity specification.
![Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1428629-71-3 | 97.0% | 313.30 g/mol | C14H19NO7 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203474.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1428629-71-3 | 97.0% | 313.30 g/mol | C14H19NO7 | 250 MG
Propargyl-PEG3-NHS ester is an amine-reactive N-hydroxysuccinimide (NHS) ester with a terminal propargyl alkyne and a three-unit PEG spacer. It is designed for bioconjugation and linker chemistry, enabling amide bond formation with primary amines and copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide partners.
- Amine-reactive NHS ester for stable amide bond formation.
- Terminal alkyne enables CuAAC click chemistry.
- Three-unit PEG spacer provides flexibility and solubility.
- Suitable for PROTAC and antibody-drug conjugate linker synthesis.
- High purity (97.0% by NMR) and molecular weight 313.30 g/mol.
Medchemexpress LLC 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol | 1422023-54-8 | ≥97.0% | 250 MG
Propargyl-PEG7-alcohol is a chemical compound identified by CAS number 1422023-54-8. It has a molecular formula of C17H32O8 and a molecular weight of 364.43. This compound is typically found as a colorless to light yellow liquid, with a purity of ≥97.0%. It is intended for research use only.
- Molecular formula: C17H32O8
- Molecular weight: 364.43
- Purity: ≥97.0%
- Appearance: colorless to light yellow liquid
- Storage for pure form: 3 years at -20°C, 2 years at 4°C
- Storage in solvent: 6 months at -80°C, 1 month at -20°C