Acetylides
eMolecules AstaTech / METHYL 5-ETHYNYLPYRIDINE-2-CARBOXYLATE / 1g / 222802523 / 24407 / 95.000 / 17880-61-4 / MFCD13189756 / 161.160 / C9H7NO2
AstaTech / METHYL 5-ETHYNYLPYRIDINE-2-CARBOXYLATE / 1g / 222802523 / 24407 / 95.000 / 17880-61-4 / MFCD13189756 / 161.160 / C9H7NO2
eMolecules 3-Bromo-5-ethynylpyridine | 866683-52-5 | MFCD10698137 | 1g
Combi-Blocks | 3-Bromo-5-ethynylpyridine | 1g | 457921716 | ST-0580 | 95.000 | 866683-52-5 | MFCD10698137 | 182.020 | C7H4BrN
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Medchemexpress LLC Propargyl-PEG4-amine 1g | 1013921-36-2 | 1 G
Propargyl-PEG4-amine is an alkyne-functional tetraethylene glycol amine used as a linker for bioconjugation and PROTAC synthesis. It provides an alkyne handle for copper-catalyzed azide-alkyne cycloaddition and a terminal primary amine for further coupling reactions.
- Provides an alkyne handle for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Contains a tetraethylene glycol spacer to improve solubility and flexibility.
- Offers a terminal primary amine for amide bond formation and other coupling chemistries.
- High purity suitable for synthesis and conjugation (99.7%).
- Molecular weight 231.29 g/mol; formula C11H21NO4.
eMolecules Broadpharm / Bis-propargyl-PEG10 / 250mg / 296213608 / BP-22828 / 98.000 / 1351373-47-1 / MFCD28976686 / 490.590 / C24H42O10
Broadpharm / Bis-propargyl-PEG10 / 250mg / 296213608 / BP-22828 / 98.000 / 1351373-47-1 / MFCD28976686 / 490.590 / C24H42O10
eMolecules 4-(Propargylaminocarbonyl)phenylboronic acid pinacol ester | 1218790-49-8 | MFCD11113041 | 1g
Combi-Blocks | 4-(Propargylaminocarbonyl)phenylboronic acid pinacol ester | 1g | 117546930 | PN-9139 | 96.000 | 1218790-49-8 | MFCD11113041 | 285.150 | C16H20BNO3
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eMolecules Propargyl Butylcarbamate | 76114-73-3 | MFCD06411065 | 500mg
Toronto Research Chemicals | Propargyl Butylcarbamate | 500mg | 483432557 | P762590 | | 76114-73-3 | MFCD06411065 | 155.197 | C8H13NO2
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Medchemexpress LLC 4-Ethynylaniline | 14235-81-5 | 117.15 | 1 ML
4-Ethynylaniline is a biochemical reagent used in life science research. It serves as a click chemistry reagent, specifically containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- Used as a biochemical reagent
- Utilized in life science research
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with azide-containing molecules
eMolecules 2-METHYL-6-(TRIFLUOROMETHOXY)-1H-INDOLE | 57330-49-1 | MFCD11111712 | 1g
AstaTech | 2-METHYL-6-(TRIFLUOROMETHOXY)-1H-INDOLE | 1g | 200616773 | 69490 | 95.000 | 57330-49-1 | MFCD11111712 | 215.175 | C10H8F3NO
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Medchemexpress LLC Bis-propargyl-PEG4 | 159428-42-9 | 95.6% | 5 G
Bis-propargyl-PEG4 is a PEG-based bifunctional linker featuring terminal propargyl (alkyne) groups, designed for conjugation chemistry and PROTAC construction. It provides a short, flexible spacer for joining two ligands via click chemistry.
- Bifunctional PEG4 linker with terminal alkyne groups.
- Enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Useful for PROTAC synthesis and dimer formation.
- Low molecular weight (270.32 g/mol) for compact linker design.
- Stable under recommended storage conditions when kept dry and refrigerated.
eMolecules 2-Fluoro-5-(trifluoromethoxy)benzyl alcohol | 344411-08-1 | MFCD04115889 | 1g
Combi-Blocks | 2-Fluoro-5-(trifluoromethoxy)benzyl alcohol | 1g | 388720261 | QI-2759 | 96.000 | 344411-08-1 | MFCD04115889 | 210.128 | C8H6F4O2
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Medchemexpress LLC Bis-propargyl-PEG8 250mg | 1092554-87-4 | 250 MG
Bis-propargyl-PEG8 is a PEG-based PROTAC linker with two terminal propargyl (alkyne) groups used as a click-chemistry reagent to join azide-bearing fragments via copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is supplied in small-scale laboratory pack sizes for research use.
- Contains two terminal alkyne (propargyl) groups.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- PEG8 spacer provides a flexible, hydrophilic linker.
- Supplied in multiple small laboratory pack sizes.
- Molecular formula C22H38O9; molecular weight 446.53.
Medchemexpress LLC Propargyl-PEG12-OH 250mg | 1036204-61-1 | 584.69 | C27H52O13 | 250 MG
Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs Propargyl-PEG12-OH is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | >95.0% | 302.36 g/mol | C15H26O6 | 5 MG
Propargyl-PEG3-OCH2-Boc is a Boc-protected PEG3 linker bearing a terminal propargyl (alkyne) group. It is a click-chemistry building block used for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and is commonly applied in PROTAC synthesis, bioconjugation, and small-molecule linker assembly. The PEG3 spacer improves solubility and provides flexibility for efficient conjugation.
- Boc-protected terminal alkyne suitable for CuAAC click reactions.
- Three-unit PEG spacer enhances solubility and conformational flexibility.
- Suitable for PROTAC linker synthesis and general bioconjugation.
- Compatible with common organic solvents such as DMSO and DMF.
- Available in research-scale quantities for synthesis and optimization.