Acetylides
Medchemexpress LLC Propargyl-PEG8-OH | 1351556-81-4 | 100 MG
Propargyl-PEG8-OH is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This click chemistry reagent contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 5 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 174.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
Medchemexpress LLC Propargyl-PEG2-bromi 250mg
Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Propargyl-PEG2-bromide is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 1 g | CAS 171486-61-6 | MDL MFCD28976150
2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 60 mL Glass (Septum)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 38.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C
eMolecules 156425-08-0 | 4-Chloro-5-(trifluoromethoxy)benzene-1,2-diamine | MFCD23703477 | 1g
Ambeed | 5-(((S)-1-((2S4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-33-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid | 50mg | 788438991 | A1595811 | 2172819-73-5 | 544.670 | C27H36N4O6S
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eMolecules 2055042-83-4 | Propargyl-PEG9-bromide | Broadpharm | MFCD29079385 | 515.438 | C21H39BrO9 | 98.000 | BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 500mg | 298819246
Propargyl-PEG9-bromide | Broadpharm | 2055042-83-4 | MFCD29079385 | 515.438 | C21H39BrO9 | 98.000 | BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 500mg | 298819246
Medchemexpress LLC (S)-VQW-765 ((S)-AQW-051) | 98.0% | 294.39 | 5 MG
(S)-VQW-765 ((S)-AQW-051) is an orally active, selective, and effective α7 nicotinic ACh receptor (nAChR) partial agonist. It has potential applications in cognitive disorders related to neurological diseases, such as Alzheimer's disease or schizophrenia.
- Orally active, selective, and effective α7 nAChR partial agonist
- Potential applications in cognitive disorders
- Suitable for neurological diseases like Alzheimer's or schizophrenia
Medchemexpress LLC Propargyl-PEG4-acid | 1415800-32-6 | 97.0% | 10 G
Propargyl-PEG4-acid is a PEG-based PROTAC linker. It can be used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and analogue PROTAC 3, which causes BTK degradation. Propargyl-PEG4-acid is also a click chemistry reagent, featuring an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in synthesis of BTK-IAP PROTACs
- PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells
- Click chemistry reagent with Alkyne group
- Can undergo CuAAc with Azide groups
eMolecules 2949-26-0 | Naphthylene-2-acetylene | Oakwood Chemicals | MFCD00870424 | 152.196 | C12H8 | 98.000 | C#Cc1ccc2ccccc2c1 | 1g | 486555901
Naphthylene-2-acetylene | Oakwood Chemicals | 2949-26-0 | MFCD00870424 | 152.196 | C12H8 | 98.000 | C#Cc1ccc2ccccc2c1 | 1g | 486555901
Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | ≥98.0% | 187.24 | 50 MG
Propargyl-PEG3-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs use the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an alkyne group for CuAAc reactions with azide groups
Medchemexpress LLC Propargyl-PEG10-acid | 2055022-18-7 | 98.0% | 524.60 | 500 MG
Propargyl-PEG10-acid is a PEG derivative that features a propargyl group along with a terminal carboxylic acid. It functions as a click chemistry reagent, containing an Alkyne group, and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules that possess Azide groups.
- PEG derivative
- Features a propargyl group
- Contains a terminal carboxylic acid
- Functions as a click chemistry reagent
- Contains an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Suitable for PROTAC synthesis
- Used as a biochemical assay reagent
Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | 302.36 | 25 MG
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Used in the synthesis of PROTACs
- For research use only
Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | MFCD28334507 | >98.0% | 407.50 g/mol | C19H37NO8 | 50 MG
Propargyl-PEG8-NH2 is a heterobifunctional PEG8 linker featuring a terminal propargyl (alkyne) group and a primary amine; it is used for click chemistry (CuAAC) and amine derivatization in bioconjugation workflows such as PROTAC and ADC synthesis.
- Contains terminal propargyl (alkyne) group for copper-catalyzed azide-alkyne cycloaddition.
- Contains a primary amine for further derivatization and amide or carbamate coupling.
- Formula C19H37NO8 and molecular weight 407.50 g/mol.
- High purity, specified as ≥98.0%.
- Common applications include ADC linkers, PROTAC linkers, and general bioconjugation building blocks.
- CAS number 1196732-52-1 for chemical identification.
Accela Chembio Inc MF: C10H8O2 | MW: 160.17 | >97% | Flash Point: 92? | BP: 239.4? at 760 mmHg.
MF: C10H8O2 | MW: 160.17 | >97% | Flash Point: 92? | BP: 239.4? at 760 mmHg.