Acetylides

Medchemexpress LLC Propargyl-PEG7-NHS ester | 2093152-77-1 | MFCD29041936 | >95.0% | 489.51 g/mol | C22H35NO11 | 1 G

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Propargyl-PEG7-NHS ester is an alkyne-functional PEG7 N-hydroxysuccinimide (NHS) ester used as a bifunctional linker for bioconjugation. It couples to primary amines via NHS chemistry and provides a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition, making it suitable for ADC, PROTAC, and general labeling applications.

• Alkyne-functional terminal enables click chemistry.
• NHS ester reacts with primary amines for covalent coupling.
• PEG7 spacer increases solubility and provides flexibility.
• Molecular weight about 489.51 g/mol and formula C22H35NO11.
• Typical applications include ADC linkers, PROTAC synthesis, and peptide or protein labeling.

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Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 250 MG

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Propargyl-PEG9-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent that contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Click chemistry reagent
• Alkyne group for reactions
• Used in PROTAC synthesis
• Applicable in cancer research
• Supports cancer targeted therapy
• PROTAC linker

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Medchemexpress LLC E -Pent-2-enal 50g

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(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners

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Chemscene ChemScene | Boc-Propargylamine | 25G | CS-M0556 | 0.98 | 92136-39-5| MFCD07367245 | 155.19

ChemScene | Boc-Propargylamine | 25G | CS-M0556 | 0.98 | 92136-39-5| MFCD07367245 | 155.19

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Medchemexpress LLC E -Pent-2-enal 100g

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(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners

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Medchemexpress LLC E -Pent-2-enal 10g

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(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners

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eMolecules​ 2007921-20-0 | 3-AMINOBICYCLO[1.1.1]PENTAN-1-OL HCL | AstaTech | MFCD28501812 | 135.590 | C5H10ClNO | 95.000 | Cl.NC12CC(O)(C1)C2 | 0.1g | 323615419

3-AMINOBICYCLO[1.1.1]PENTAN-1-OL HCL | AstaTech | 2007921-20-0 | MFCD28501812 | 135.590 | C5H10ClNO | 95.000 | Cl.NC12CC(O)(C1)C2 | 0.1g | 323615419

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Medchemexpress LLC 2-[2-(2-propynyloxy)ethoxy]ethanamine | 944561-44-8 | MFCD19160595 | 98.9% | 143.18 g/mol | C7H13NO2 | 25 G

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Propargyl-PEG2-amine is a propargyl-terminated polyethylene glycol (PEG2) amine linker used for bioconjugation and synthetic chemistry. It is commonly used as a non-cleavable ADC linker, as a PEG-based PROTAC linker, and as a terminal alkyne reagent for copper-catalyzed azide-alkyne cycloaddition (click chemistry).

• Non-cleavable ADC linker for antibody-drug conjugate synthesis.
• Suitable as a PEG-based PROTAC linker.
• Terminal alkyne enables CuAAC click reactions with azides.
• Primary amine allows amide coupling and NHS-ester chemistry.
• Molecular formula C7H13NO2 and molecular weight 143.18 g/mol.
• High reported purity (manufacturer batch example ~98.9%), batch-dependent.
• Available in multiple pack sizes, including 25 G and larger quantities.

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Medchemexpress LLC Propargyl-PEG4-Br | 1308299-09-3 | 97.0% | 250 MG

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Propargyl-PEG4-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It also functions as a non-cleavable ADC linker for antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, featuring an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules.

• PEG-based PROTAC linker
• Non-cleavable ADC linker
• Click chemistry reagent
• Contains an alkyne group
• Enables copper-catalyzed azide-alkyne cycloaddition

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eMolecules​ 1936643-30-9 | 3-aminobicyclo[1.1.1]pentane-1-carbonitrile | Pharmablock | MFCD30719357 | 108.144 | C6H8N2 | 97.000 | NC12CC(C1)(C2)C#N | 2.5g | 686934446

3-aminobicyclo[1.1.1]pentane-1-carbonitrile | Pharmablock | 1936643-30-9 | MFCD30719357 | 108.144 | C6H8N2 | 97.000 | NC12CC(C1)(C2)C#N | 2.5g | 686934446

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eMolecules​ 569672-28-2 | 2-BROMO-5-ETHYNYLPYRIDINE | AstaTech | MFCD13189724 | 182.020 | C7H4BrN | 95.000 | Brc1ccc(cn1)C#C | 1g | 200615070

2-BROMO-5-ETHYNYLPYRIDINE | AstaTech | 569672-28-2 | MFCD13189724 | 182.020 | C7H4BrN | 95.000 | Brc1ccc(cn1)C#C | 1g | 200615070

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eMolecules​ 344411-08-1 | 2-Fluoro-5-(trifluoromethoxy)benzyl alcohol | Combi-Blocks | MFCD04115889 | 210.128 | C8H6F4O2 | 96.000 | OCc1cc(OC(F)(F)F)ccc1F | 1g | 388720261

2-Fluoro-5-(trifluoromethoxy)benzyl alcohol | Combi-Blocks | 344411-08-1 | MFCD04115889 | 210.128 | C8H6F4O2 | 96.000 | OCc1cc(OC(F)(F)F)ccc1F | 1g | 388720261

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eMolecules​ 1421676-62-1 | Propargyl-PEG25-acid | Broadpharm | MFCD29079427 | 1185.399 | C54H104O27 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 50mg | 298819371

Propargyl-PEG25-acid | Broadpharm | 1421676-62-1 | MFCD29079427 | 1185.399 | C54H104O27 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 50mg | 298819371

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Medchemexpress LLC Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 1,1-dimethylethyl ester | 1807503-80-5 | 95.0% | 250 MG

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This compound is a polyethylene glycol (PEG)-based PROTAC linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). It acts as a click chemistry reagent due to its alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules.

• Application: Can be employed in the synthesis of PROTACs.
• Characteristics: It contains an alkyne group and can participate in copper-catalyzed azide-alkyne cycloaddition.

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Medchemexpress LLC Bis-PEG1-C-PEG1-CH2COOH | 2358775-67-2 | MFCD22381072 | 95.0% | 350.40 | C16H30O8 | 5 MG

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Bis-PEG1-C-PEG1-CH2COOH is a PEG-based bifunctional linker bearing a terminal carboxylic acid; it serves as a building block for the synthesis of PROTACs and other conjugates. The material is supplied as an off-white to yellow oil, and is typically offered at research-grade purity for small-scale synthetic work.

• PEG-based bifunctional linker for PROTAC and conjugate synthesis.
• Terminal carboxylic acid enables standard amide or ester coupling reactions.
• Low molecular weight building block (MW 350.4) for modular design.
• Supplied as an off-white to yellow oil suitable for solution-phase synthesis.
• High purity appropriate for research applications (95.0%).
• Available in small pack sizes for screening and library synthesis.

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