Acetylides
eMolecules 4-Chloro-2-(trifluoromethoxy)-DL-phenylalanine | 1435806-19-1 | MFCD19687214 | 1g
Apollo Scientific | 4-Chloro-2-(trifluoromethoxy)-DL-phenylalanine | 1g | 562459894 | PC302857 | | 1435806-19-1 | MFCD19687214 | 283.630 | C10H9ClF3NO3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
eMolecules 2-Fluoro-4-(trifluoromethoxy)-DL-phenylalanine | 1391008-15-3 | MFCD16652500 | 1g
Apollo Scientific | 2-Fluoro-4-(trifluoromethoxy)-DL-phenylalanine | 1g | 562456457 | PC302801 | | 1391008-15-3 | MFCD16652500 | 267.180 | C10H9F4NO3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC 4,7,10,13,16,19,22-heptaoxapentacos-24-ynoic acid | 2093154-00-6 | ≥98.0% | 392.44 | C18H32O9 | 250 MG
Propargyl-PEG7-acid is a PEG-based linker and click chemistry reagent containing a terminal alkyne that enables copper-catalyzed azide-alkyne cycloaddition. It is used as a PROTAC linker and as a cleavable linker in antibody-drug conjugate synthesis.
- Contains terminal alkyne suitable for CuAAc
- PEG7 spacer provides solubility and conformational flexibility
- Applicable as a cleavable linker for ADC synthesis
- High purity: ≥98.0% (NMR)
- Available in small-scale pack sizes for research use
eMolecules 5-Chloro-2-(trifluoromethoxy)benzyl alcohol | 874821-52-0 | MFCD11519357 | 1g
Apollo Scientific | 5-Chloro-2-(trifluoromethoxy)benzyl alcohol | 1g | 562461133 | PC302354 | | 874821-52-0 | MFCD11519357 | 226.580 | C8H6ClF3O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Propargyl-PEG1-SS-PEG1-t-butyl ester | 1807518-78-0 | MFCD28505559 | >98.0% | 320.47 g/mol | C14H24O4S2 | 10 MG
Propargyl-PEG1-SS-PEG1-t-butyl ester is a cleavable PEG-based linker containing terminal propargyl (alkyne) groups and a disulfide bond. It is used in bioconjugation workflows such as antibody-drug conjugate and PROTAC synthesis, and as a click-chemistry handle for azide-alkyne cycloaddition.
- Cleavable disulfide linkage allows intracellular reduction and payload release.
- Terminal propargyl groups enable copper-catalyzed and strain-promoted click reactions.
- High purity (>98.0%) suitable for synthetic chemistry applications.
- Molecular weight 320.47 g/mol and formula C14H24O4S2.
- Available in small research quantities (5 mg, 10 mg, 25 mg) for lab-scale synthesis.
Medchemexpress LLC E -Pent-2-enal 25g
(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners
Medchemexpress LLC Bis-propargyl-PEG1 | 40842-04-4 | 98.0% | 138.16 | 100 MG
Bis-propargyl-PEG1 is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. This click chemistry reagent contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Suitable for PROTAC synthesis
Medchemexpress LLC Propargyl-PEG1-Boc | 488150-84-1 | 97.0% | 184.23 | 100 MG
Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker, a click chemistry reagent, utilized in the synthesis of PROTACs. It contains an Alkyne group enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups.
- Used as a PROTAC linker for synthesizing PROTACs.
- Functions as a click chemistry reagent.
- Contains an Alkyne group for CuAAc reactions.
- Enables reactions with molecules possessing Azide groups.
- Supports the PROTAC mechanism of action, which involves the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC N-(Propargyl-PEG4)-biocytin | 2055042-71-0 | 98.0% | C28H46N4O9S | 250 MG
N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs consist of two different ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other the protein of interest, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Supports targeted protein degradation
Medchemexpress LLC Propargyl-PEG3-NHS ester | 1428629-71-3 | MFCD23726610 | 97.0% | 313.30 g/mol | C14H19NO7 | 100 MG
Propargyl-PEG3-NHS ester is an NHS-activated PEG3 linker bearing a terminal propargyl (alkyne) group used for bioconjugation and linker synthesis. It couples to primary amines to form amide bonds and enables click chemistry via CuAAC.
- Reactive NHS ester for selective coupling to primary amines.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Three-unit PEG spacer improves solubility and flexibility.
- High purity (97.0% by NMR) suitable for research applications.
- Soluble in DMSO; store under nitrogen at -20°C for stability.
Medchemexpress LLC D(+)-Raffinose pentahydrate | 17629-30-0 | 594.51 | 5 G
D(+)-Raffinose pentahydrate is an orally active inhibitor of LecA (Kd = 32 μM) and GtfC. It functions by reducing cyclic diguanylate (c-di-GMP) through increased activity of a c-di-GMP specific phosphodiesterase and interferes with GTF function. This compound decreases IL-4 and IL-5 mRNA, exhibits biofilm-inhibitory activity against *Pseudomonas aeruginosa* and *Streptococcus mutans*, and inhibits allergic airway eosinophilia. It is intended for research use only and not for sale to patients.
- Orally active inhibitor of LecA and GtfC
- Reduces cyclic diguanylate (c-di-GMP)
- Interferes with GTF function
- Decreases IL-4 and IL-5 mRNA
- Exhibits biofilm-inhibitory activity against *Pseudomonas aeruginosa* and *Streptococcus mutans*
- Inhibits allergic airway eosinophilia
eMolecules 2-Methyl-4-(trifluoromethoxy)phenylacetic acid | 886763-11-7 | MFCD07368720 | 5g
Apollo Scientific | 2-Methyl-4-(trifluoromethoxy)phenylacetic acid | 5g | 562425878 | PC1066 | 98.000 | 886763-11-7 | MFCD07368720 | 234.174 | C10H9F3O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Propargyl-peg8-nh2 | 1196732-52-1 | ≥98.0% | 407.50 | C19H37NO8 | 25 MG
Propargyl-PEG8-NH2 is a polyethylene glycol (PEG) based bifunctional linker bearing a terminal propargyl (alkyne) group and a primary amine. It is used for bioconjugation and as a non-cleavable linker in ADC and PROTAC synthesis, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and amine-based coupling reactions.
- Contains terminal alkyne (propargyl) and primary amine functional groups.
- PEG8 spacer provides flexibility and solubility for conjugates.
- Suitable for CuAAC click chemistry with azide-containing partners.
- High purity (≥98.0%) for research and conjugation workflows.
- Molecular weight approximately 407.50 Da and formula C19H37NO8.
- Available in multiple package sizes to suit synthesis scale.