Acetylides
Medchemexpress LLC Propargyl-peg6-acid | 1951438-84-8 | 348.39 g/mol | C16H28O8 | 50 MG
Propargyl-PEG6-acid is a PEG6-based linker and click-chemistry reagent containing a terminal propargyl (alkyne) group and a carboxylic acid. It is used to introduce a PEG6 spacer in the synthesis of PROTACs and antibody-drug conjugates (ADCs) and undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation.
- Used as PEG6 spacer in PROTAC and ADC synthesis.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Molecular weight 348.39 g/mol; formula C16H28O8.
- CAS number 1951438-84-8 for unambiguous identification.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Propargyl-PEG1-NH2 100mg | 122116-12-5 | 99.13 g/mol | C5H9NO | 100 MG
Propargyl-PEG1-NH2 is a short polyethylene glycol linker bearing a terminal propargyl (alkyne) group and a primary amine. It is used as a bifunctional coupling handle in medicinal chemistry and bioconjugation workflows, and is compatible with click chemistry for assembling conjugates such as PROTACs.
- Short PEG1 linker with terminal alkyne and primary amine.
- Facilitates copper-catalyzed azide-alkyne cycloaddition (click) conjugations.
- High purity (98.8%) suitable for research and synthetic applications.
- Available in small research pack sizes for rapid screening and synthesis.
- Store at 4°C and protect from light; aliquot prepared solutions to avoid repeated freeze-thaw cycles.
Medchemexpress LLC Ws-917 | 10 MG
WS-917 is a small-molecule research compound characterized as a potent, orally active ABCB1 (P-glycoprotein) modulator. It enhances ABCB1 ATPase activity, promotes CD8+ T-cell activation, and has been shown to potentiate the antitumor effect of paclitaxel when combined with anti-PD-1 therapy. Intended for research use; follow appropriate storage and handling.
- Potent, orally active ABCB1 modulator.
- Enhances ABCB1 ATPase activity.
- Promotes CD8+ T-cell activation.
- Shown to enhance paclitaxel antitumor effect in combination with anti-PD-1 therapy.
- Molecular formula C16H13N5OS2; molecular weight 355.44 g/mol.
- Recommended storage: 4°C under nitrogen; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month) under nitrogen.
Medchemexpress LLC Propargyl-PEG1-bromide | 18668-74-1 | MFCD00099299 | 98.0% | 163.01 | C5H7BrO | 1 G
Propargyl-PEG1-bromide is an alkyne-functionalized short polyethylene glycol (PEG) linker bearing a terminal bromide. It is used in bioconjugation and medicinal chemistry to introduce a clickable propargyl handle while providing a reactive leaving group for further substitution, enabling efficient incorporation of a short PEG spacer into synthetic linkers and small-molecule constructs.
- Provides an alkyne (propargyl) handle for click chemistry.
- Contains a terminal bromide for nucleophilic substitution reactions.
- Short PEG1 spacer improves solubility and minimizes steric hindrance.
- Molecular weight ~163.01 g/mol for predictable stoichiometry.
- Suitable for linker synthesis, bioconjugation, and small-molecule modification.
eMolecules 1261673-90-8 | 4-Chloro-2-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | MFCD18393819 | 226.580 | C8H6ClF3O2 | 98.000 | OCc1ccc(Cl)cc1OC(F)(F)F | 1g | 562456700
4-Chloro-2-(trifluoromethoxy)benzyl alcohol | Apollo Scientific | 1261673-90-8 | MFCD18393819 | 226.580 | C8H6ClF3O2 | 98.000 | OCc1ccc(Cl)cc1OC(F)(F)F | 1g | 562456700
Chem-Impex International, Inc. 4-Ethynylaniline | MFCD00168824 | 25G
4-Ethynylaniline, MFCD00168824, 25G
Aobchem 1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 500mg
1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 500mg
Aobchem 1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 1g
1-(3 5-Dimethoxyphenyl)-1-pentanone | ≥97% | CAS 5333-29-9 | C13H18O3 | 1g
Chem-Impex International, Inc. 4-Ethynylaniline | MFCD00168824 | 5G
4-Ethynylaniline, MFCD00168824, 5G