Hydrobromides
TARGETMOL CHEMICALS INC PIFITHRIN-BETA HYDROBROM 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pifithrin-(beta) hydrobromide (Cyclic PFT-(alpha)) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 uM). purity: 99%
Apexbio Technology LLC A 61603 hydrobromide 107756-30-9 5mg
A 61603 hydrobromide (CAS 107756-30-9) is a potent and highly selective agonist of the 1A-adrenergic receptor one of the 1-adrenergic receptor subtypes involved in cellular growth and proliferation Compared to its activity at 1B- and 1D-adrenergic receptors A 61603 demonstrates approximately 35-fold higher potency for 1A-AR In cellular assays it robustly induces phosphoinositide hydrolysis in 1A-AR-expressing fibroblasts (pEC50 8 24) and in neonatal rat cardiomyocytes it increases calcium transient frequency in a dose-dependent manner (EC50 6 9 nM) In vascular models A 61603 markedly elevates perfusion pressure demonstrating significantly greater efficacy than noradrenaline This compound serves as a valuable tool for delineating 1A-AR-mediated signaling and vascular regulation
Medchemexpress LLC Guvacoline hydrobrom 25mg | 17210-51-4 | 25 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid found in Areca triandra. It is used as a research reagent and functions as a weak full agonist of atrial and ileal muscarinic acetylcholine receptors (mAChR).
- Acts as a weak full agonist of atrial and ileal muscarinic receptors.
- White to off-white solid physical form.
- Molecular formula C7H12BrNO2 and molecular weight 222.08.
- Purity typically around 96.09% by HPLC.
- Store sealed at 4°C and protect from moisture and light; in solution store at -80°C for long-term.
- Supplied in small milligram pack sizes for laboratory research.
TARGETMOL CHEMICALS INC REMODELIN HYDROBROMIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. purity: 99%
Medchemexpress LLC Halofuginone (hydrobromide) | 64924-67-0 | MFCD00946455 | 100.0% | 495.59 g/mol | C16H18Br2ClN3O3 | 10 MG
Halofuginone hydrobromide is the hydrobromide salt of halofuginone, a febrifugine-derived small molecule that competitively inhibits prolyl-tRNA synthetase and is supplied for research applications studying fibrosis, inflammation, malaria, and cancer. It is provided as a white to off-white solid with high purity and defined storage and solvent recommendations.
- Hydrobromide salt for improved handling and solubility.
- Competitive prolyl-tRNA synthetase inhibitor used in mechanistic research.
- High purity suitable for research applications.
- White to off-white solid, soluble in DMSO (≈50 mg/mL) and water (≈2.6 mg/mL).
- Store sealed and away from moisture; in solution keep at -80°C for long-term stability.
- Applicable for preclinical studies of fibrosis, inflammation, malaria, and cancer pathways.
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g·mol⁻¹ | C6H13Br2N3S | 5 MG
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, a selective histamine receptor agonist used in pharmacology and receptor research. It is supplied as a purified solid for use in in vitro and in vivo assays to probe histamine receptor function and signaling.
- High reported purity: 99.6%.
- Molecular weight 319.07 g·mol⁻¹.
- Supplied as a solid dihydrobromide salt.
- Suitable for histamine receptor pharmacology and assay work.
- Available in small milligram pack sizes for research use.
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 5mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation