Hydrobromides
Selleck Chemical LLC Homatropine Methylbromide S4024-1g
Homatropine Methylbromide is muscarinic AChR antagonist inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162 5 nM and 170 3 nM respectively
Sigma Organic Chemistry 4-Oxo-L-proline hydrobromide | 1G | 75776-67-9 | MFCD12024572
4-Oxo-L-proline hydrobromide, 1G
About This Item:
Storage: 2-8C
Selleck Chemical LLC Remodelin hydrobromide
Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor
Apexbio Technology LLC 6-OHDA HYDROBROMIDE 50MG
6-Hydroxydopamine hydrobromide (CAS 636-00-0) commonly referred to as 6-OHDA hydrobromide is a catecholamine-derived neurotoxin frequently used in neuroscience research to induce selective dopaminergic neuronal degeneration Upon administration it generates intracellular reactive oxygen species (ROS) activating apoptotic pathways via caspase-3 -8 and -9 as demonstrated in PC12 cell studies In rodent models targeted injection into substantia nigra striatum or medial forebrain bundle leads to loss of tyrosine hydroxylase-positive neurons and resultant locomotor dysfunction resembling symptoms observed in Parkinson s disease Consequently it serves as a valuable tool for elucidating dopaminergic dysfunction mechanisms and evaluating therapeutic candidates
TARGETMOL CHEMICALS INC VORTIOXETINE HYDROBROMID 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS) inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50 15/33/3.7/19/1.6 nM). purity: 99%
TARGETMOL CHEMICALS INC PIFITHRIN-BETA HYDROBROM 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pifithrin-(beta) hydrobromide (Cyclic PFT-(alpha)) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 uM). purity: 99%
AdipoGen 5 7-Dihydroxytryptamine HBr
Chemical. CAS 31363-74-3 free base. Formula C10H12N2O2 . HBr. MW 192.2 . 80.9. Synthetic Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.
AdipoGen 5 7-Dihydroxytryptamine HBr
Chemical. CAS 31363-74-3 free base. Formula C10H12N2O2 . HBr. MW 192.2 . 80.9. Synthetic Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.
TARGETMOL CHEMICALS INC Galanthamine hydrobromide
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors. Purity 99.19%
Cayman Chemical FenoterolhydrobromIde 10mg
A brominated derivative of guanosine that has been used to reduce the conformational heterogeneity of RNA to potentially enhance its function reported to activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects
Selleck Chemical LLC Homatropine Bromide S4025-50mg
Homatropine Bromide is an muscarinic AChR antagonist inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162 5 nM and 170 3 nM respectively
Selleck Chemical LLC Arecoline HBr S2614-1g
Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.