Hydrobromides
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g·mol⁻¹ | C6H13Br2N3S | 25 MG
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, a histamine receptor agonist active at H1-H4 receptors. It is supplied as a solid and in ready-to-use DMSO solution formats for pharmacological research, and includes storage recommendations for both solids and stock solutions.
TARGETMOL CHEMICALS INC Arecoline 500MG
Also available in 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Arecoline is a natural alkaloid derived from areca nut in the palm family and is a potent nicotine and partial agonist of muscarinic acetylcholine receptors. Arecoline has anti-anxiety and anti-parasitic activity, can induce oxidative stress and can be used to study Alzheimer's disease and Alzheimer's disease. Purity 99.28%
Medchemexpress LLC (RS)-AMPA hydrobromide | 171259-81-7 | 99.5% | 267.08 g/mol | C7H11BrN2O4 | 10 MG
(RS)-AMPA hydrobromide is the hydrobromide salt of (RS)-AMPA, a glutamate analogue and selective agonist of AMPA-type glutamate receptors. Supplied as a white to off-white solid for research use in neuroscience and pharmacology studies where a water-soluble AMPA receptor agonist is required.
- Selective AMPA receptor agonist.
- CAS number 171259-81-7.
- Molecular weight 267.08 g/mol.
- Purity 99.5%.
- White to off-white solid.
- Solubility: DMSO 50 mg/mL; H2O 5 mg/mL (may require ultrasonic).
- Storage: sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 10mM (in 1mL DMSO)
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels
Apexbio Technology LLC Scopolamine hydrobromide 114-49-8 100mg
Scopolamine hydrobromide (114-49-8) is a small-molecule antagonist targeting muscarinic acetylcholine receptors and serotonin 5-HT3 receptors It is designed to reversibly block these receptors thereby modulating cholinergic and serotonergic signaling pathways Scopolamine hydrobromide exerts its biological activity primarily through reversible antagonism of muscarinic receptors and inhibition of serotonin 5-HT3 receptor responses In receptor binding studies Scopolamine hydrobromide demonstrates antagonistic activity with reported IC50 values generally ranging from nanomolar to micromolar concentrations depending on the receptor subtype and experimental conditions Based on these pharmacological properties Scopolamine hydrobromide holds research potential in studies of neurotransmission cholinergic signaling gastrointestinal motility assays cognitive impairment models and emesis reflex investigations
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g/mol | C6H13Br2N3S | 50 MG
Amthamine dihydrobromide is a research-grade histamine receptor agonist provided as the dihydrobromide salt. It is used in pharmacology and toxicology research to study histamine receptor activation and downstream physiological effects in vitro and in vivo.
- Selective histamine H2 receptor agonist.
- High chemical purity suitable for research applications.
- Available as a solid for flexible dosing and formulation.
- Includes molecular and CAS identifiers for unambiguous compound identification.
Medchemexpress LLC Arecoline | 63-75-2 | MFCD00005704 | 1 ML
Arecoline is a naturally occurring psychoactive alkaloid that is brain-penetrant and orally active. It acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors. This compound has been observed to exhibit stimulation, alertness, anxiolysis, and anti-parasitic effects, though it can also induce oxidative stress.
- Purity: 99.84%
- Molecular weight: 155.19
- Formula: C8H13NO2
- Appearance: liquid
- Color: light yellow to brown
- Structure classification: alkaloids, piperidine alkaloids
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors
- Induces stimulation, alertness, anxiolysis, and anti-parasitic effects
- Can alleviate anxiety and depression in CFA-induced mice
Apexbio Technology LLC Imetit dihydrobromide 32385-58-3 5mg
Imetit dihydrobromide (CAS 32385-58-3) is a potent high-affinity agonist of histamine H3 and H4 receptors demonstrating Ki values of 0 3 nM and 2 7 nM respectively Functionally it replicates histaminergic effects by inducing morphological changes in eosinophils with an EC50 of 25 nM Owing to its selective receptor activity Imetit dihydrobromide is widely employed in studies investigating allergic inflammatory processes including asthma as well as in research focused on central nervous system physiology and histamine-related pathways
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g·mol⁻¹ | C6H13Br2N3S | 5 MG
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, a selective histamine receptor agonist used in pharmacology and receptor research. It is supplied as a purified solid for use in in vitro and in vivo assays to probe histamine receptor function and signaling.
- High reported purity: 99.6%.
- Molecular weight 319.07 g·mol⁻¹.
- Supplied as a solid dihydrobromide salt.
- Suitable for histamine receptor pharmacology and assay work.
- Available in small milligram pack sizes for research use.
Apexbio Technology LLC Homatropine Bromide 51-56-9 1g
Homatropine Bromide (CAS 51-56-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It selectively inhibits muscarinic receptor-mediated responses in endothelial and smooth muscle cells with reported IC50 values of 162 5 nM and 170 3 nM for WKY-E and SHR-E cell models respectively This compound serves as a valuable tool for investigating the role of muscarinic signaling in vascular function and smooth muscle physiology within experimental research settings
Medchemexpress LLC Arecoline | 63-75-2 | 100 MG
Arecoline is a naturally brain-penetrant and orally active psychoactive alkaloid. It functions as a partial agonist of nicotinic and muscarinic acetylcholine receptors. It has been observed to exhibit stimulation, alertness, anxiolysis, and anti-parasitic effects. Research indicates it can also induce oxidative stress.
- Partial agonist of nicotinic and muscarinic acetylcholine receptors
- Exhibits stimulation and alertness
- Demonstrates anxiolysis and anti-parasitic effects
- Induces generation of reactive oxygen species
- Causes cell cycle arrest at G1/G0 phase in HaCaT cells
- Upregulates hemeoxygenase-1, ferritin light chain, glucose-6-phosphate dehydrogenase, glutamate-cysteine ligase catalytic subunit, and glutathione reductase expression
- Alleviates anxiety and depression in CFA-induced mice
Selleck Chemical LLC Remodelin hydrobromide
Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor
Selleck Chemical LLC Homatropine Methylbromide S4024-1g
Homatropine Methylbromide is muscarinic AChR antagonist inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162 5 nM and 170 3 nM respectively