Hydrobromides
Apexbio Technology LLC TC-E 5003 17328-16-4 50mg
TC-E 5003 (CAS 17328-16-4) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) exhibiting an IC50 of 1 5 M1 PRMT1 a member of the PRMT family mediates post-translational arginine methylation and is implicated in regulating diverse cellular processes Aberrant PRMT1 activity has been associated with a range of malignancies making it of interest for oncology research In cellular studies TC-E 5003 has been shown to inhibit proliferation and induce apoptosis in MCF7a breast cancer and LNCaP prostate cancer cell lines as well as attenuate androgen-induced gene expression in LNCaP cells This compound serves as a useful tool for investigating PRMT1 function and its role in cancer biology
Accela Chembio Inc 3-(bromomethyl)pyridine Hydrobromide | 5g | 4916-55-6 | MFCD01321314 | 95+% | Shelf Life: 1260 Days | Light Sensitive/nitrogen Or Argon/+4
3-(bromomethyl)pyridine Hydrobromide | 5g | 4916-55-6 | MFCD01321314 | 95+% | Shelf Life: 1260 Days | Light Sensitive/nitrogen Or Argon/+4
Apexbio Technology LLC NAN-190 hydrobromide 115338-32-4 10mg
NAN-190 hydrobromide (CAS 115338-32-4) is a selective antagonist of the serotonin 5-HT1A receptor functioning by inhibiting receptor-mediated signal transduction pathways In receptor binding assays NAN-190 hydrobromide demonstrates high affinity for 5-HT1A receptors and modulates neurotransmitter release This compound is frequently employed in neurobiology and psychiatric disorder studies to investigate 5-HT1A-related mechanisms serving as a valuable tool for elucidating serotonergic signaling and its implications in neural function and pathology
AdipoGen 2 3-Diaminopropane-1-thiol HBr
Chemical. CAS 70548-07-1. Formula C3H10N2S . 2HBr. MW 106.2 . 161.8. Synthetic Building block for synthesis.
Apexbio Technology LLC A 61603 hydrobromide 107756-30-9 10mg
A 61603 hydrobromide (CAS 107756-30-9) is a potent and highly selective agonist of the 1A-adrenergic receptor one of the 1-adrenergic receptor subtypes involved in cellular growth and proliferation Compared to its activity at 1B- and 1D-adrenergic receptors A 61603 demonstrates approximately 35-fold higher potency for 1A-AR In cellular assays it robustly induces phosphoinositide hydrolysis in 1A-AR-expressing fibroblasts (pEC50 8 24) and in neonatal rat cardiomyocytes it increases calcium transient frequency in a dose-dependent manner (EC50 6 9 nM) In vascular models A 61603 markedly elevates perfusion pressure demonstrating significantly greater efficacy than noradrenaline This compound serves as a valuable tool for delineating 1A-AR-mediated signaling and vascular regulation
Apexbio Technology LLC Imetit dihydrobromide 32385-58-3 10mg
Imetit dihydrobromide (CAS 32385-58-3) is a potent high-affinity agonist of histamine H3 and H4 receptors demonstrating Ki values of 0 3 nM and 2 7 nM respectively Functionally it replicates histaminergic effects by inducing morphological changes in eosinophils with an EC50 of 25 nM Owing to its selective receptor activity Imetit dihydrobromide is widely employed in studies investigating allergic inflammatory processes including asthma as well as in research focused on central nervous system physiology and histamine-related pathways
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 25mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation