Hydrochlorides
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | 99.7% | 269.77 g·mol^-1 | C14H20ClNO2 | 100 MG
Piperoxan hydrochloride is a research chemical described as an α2 adrenoceptor antagonist and a first-generation antihistamine, provided for laboratory pharmacology and biochemical studies. Consult the product datasheet and safety data sheet for handling, storage, and purity specifications.
- High reported purity (about 99.7%).
- Available as a solid and as a 10 mM solution in DMSO.
- Suitable for pharmacology and biochemical research applications.
- CAS number provided for unambiguous identification.
- Manufacturer datasheet and SDS available for safety and handling.
Medchemexpress LLC RS-127445 | 199864-87-4 | C17H16FN3 | 25 MG
RS-127445 is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. It exhibits 1000-fold selectivity for this receptor compared to numerous other receptor and ion channel binding sites.
- Selective and high affinity 5-HT2B receptor antagonist
- Orally bioavailable
- 1000-fold selectivity compared to other receptor and ion channel binding sites
- Potently displaces [3H]-5-HT from human recombinant 5-HT2B receptors
- Blocks 5-HT-evoked increases in intracellular calcium concentrations
Medchemexpress LLC Nisoxetine hydrochloride | 57754-86-6 | 99.9% | 25 MG
Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. It is an antidepressant and local anesthetic, capable of blocking voltage-gated sodium channels.
- Potent and selective inhibitor of noradrenaline transporter (NET)
- Functions as an antidepressant
- Acts as a local anesthetic
- Blocks voltage-gated sodium channels
Medchemexpress LLC SB-224289 hydrochloride | 180084-26-8 | 99.0% | 557.08 g/mol | C32H33ClN4O3 | 25 MG
SB-224289 hydrochloride is a research-grade small molecule that functions as a selective 5-HT1B receptor antagonist with reported anxiolytic effects. It is supplied as a white to off-white solid with high reported purity and is intended for laboratory research use, with recommended cold storage and protection from moisture.
- Selective 5-HT1B receptor antagonist for receptor pharmacology studies.
- High purity (99.0%) suitable for in vitro and in vivo research.
- Solid form, white to off-white, easy to handle and weigh.
- Stable when stored cold and protected from moisture under recommended conditions.
- Available in laboratory-scale quantities for research applications.
Medchemexpress LLC Ly 2389575 hydrochloride | 885104-09-6 | MFCD28133385 | 99.9% | 438.58 g/mol | C15H16BrCl3N4 | 100 MG
LY2389575 hydrochloride is a selective, noncompetitive negative allosteric modulator (NAM) of the metabotropic glutamate receptor 3 (mGlu3) supplied as the hydrochloride salt for research use. It is provided as a solid for in vitro and preclinical studies, including investigations of amyloid-β toxicity.
- Selective noncompetitive mGlu3 negative allosteric modulator.
- Supplied as hydrochloride salt in solid form, white to light yellow.
- High purity: 99.9%.
- Molecular formula C15H16BrCl3N4; molecular weight 438.58 g/mol.
- Available in multiple pack sizes and as a DMSO solution for convenience.
- Recommended storage: powder -20°C (long term) or 4°C (short term); in solvent -80°C.
Medchemexpress LLC GW405833 hydrochloride | 1202865-22-2 | 99.6% | 483.82 | 1 MG
GW405833 hydrochloride | 1202865-22-2 | 99.6% | 483.82 | 1 MG
Medchemexpress LLC Kevetrin hydrochloride | 66592-89-0 | 98.0% | 179.67 | 1 ML
Kevetrin hydrochloride is a potent activator of p53, inducing apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells. It exhibits preferential cytotoxic activity against blast cells.
- Potent activator of p53.
- Induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells.
- Exhibits preferential cytotoxic activity against blast cells.
Medchemexpress LLC GW405833 hydrochloride | 1202865-22-2 | 99.59% | 483.82 | 1 ML
GW405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB2) agonist. It has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. It also acts as a non-competitive CB1 antagonist, exerting its analgesic effect through a CB1 receptor dependent mechanism. It can significantly inhibit the production of cAMP stimulated by Forskolin and inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF).
- Potent, selective cannabinoid receptor 2 (CB2) agonist
- EC50 and Ki values for CB2: 0.65 nM and 3.92 nM respectively
- EC50 and Ki values for CB1: 16.1 μM and 4772 nM respectively
- Non-competitive CB1 antagonist
- Inhibits cAMP production stimulated by Forskolin
- Inhibits glycolysis by down-regulating HIF-1α
Medchemexpress LLC SKF89976A hydrochloride | 85375-15-1 | 98.7% | 371.90 | C22H26ClNO2 | 25 MG
Hydrochloride salt used as a selective inhibitor of the GABA transporter GAT-1 for in vitro research. It exhibits IC50 values of 0.28 μM (GAT-1), 137.34 μM (GAT-2), and 202.8 μM (GAT-3) in CHO cells, and is supplied as a solid and as a 10 mM solution in DMSO.
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | MFCD00673899 | 100.0% | 390.87 g/mol | C19H26ClF3N2O | 25 MG
ZT 52656A hydrochloride is a selective kappa-opioid receptor agonist supplied as the hydrochloride salt for preclinical and in vitro research, including studies of ocular pain. The compound is for research use only and is not intended for human therapeutic use.
- Selective kappa-opioid receptor agonist.
- Provided as the hydrochloride salt.
- High purity (99.98%).
- Molecular weight 390.87 g/mol.
- Chemical formula C19H26ClF3N2O.
- Appearance: solid, white to off-white.
- Available in small research sizes, e.g., 25 MG.
- Intended for preclinical and in vitro research use only.
eMolecules 167465-93-2 | 4-Aminopyrrolidin-2-one hydrochloride | MFCD11519397 | 1g
Ambeed | (2E6E10E)-371115-Tetramethylhexadeca-261014-tetraen-1-ol | 250mg | 572143834 | A682516 | 24034-73-9 | MFCD00129083 | 290.491 | C20H34O
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Medchemexpress LLC 2-(benzofuran-2-yl)-2-imidazoline hydrochloride | 89196-95-2 | MFCD00672666 | >=98.0% | 222.67 g/mol | C11H11ClN2O | 25 MG
RX 801077 hydrochloride (2-BFI) is a research compound that acts as a selective imidazoline I2 receptor (I2R) agonist. It is used in preclinical studies for its reported anti-inflammatory and neuroprotective effects and is suitable for investigations into traumatic brain injury and related neurobiology.
- Selective imidazoline I2 receptor agonist with a reported Ki of ≈70.1 nM.
- Demonstrates anti-inflammatory and neuroprotective activity in preclinical models.
- Supplied as a hydrochloride salt for improved stability and handling.
- High purity suitable for analytical and exploratory studies (≥98%).
- Well-characterized chemical data: C11H11ClN2O, molecular weight 222.67 g/mol, CAS 89196-95-2.
- Available in small-scale quantities appropriate for laboratory research.
Medchemexpress LLC uPSEM792 hydrochloride | 2341841-08-3 | 99.9% | 277.75 g/mol | C14H16ClN3O | 10 MG
uPSEM792 hydrochloride is an ultrapotent pharmacologically selective effector molecule (uPSEM) that acts as a high-affinity agonist for engineered PSAM4-GlyR receptors. It is provided for research use only and is commonly used in neuroscience experiments to selectively activate PSAM4-based receptors.
- High potency agonist for PSAM4-GlyR with reported Ki ≈ 0.7 nM.
- Suitable for in vitro and in vivo research applications.
- Supplied as the hydrochloride salt with high chemical purity.
- Available in small research-scale quantities for experimental use.
eMolecules H-Arg-4MbNA hydrochloride salt | Chem-Impex |329.404 | C17H23N5O2 | 89.000 | COc1cc(NC(=O)C(N)CCCN=C(N)N)cc2ccccc12 | 100mg | 490843132
H-Arg-4MbNA hydrochloride salt | Chem-Impex |329.404 | C17H23N5O2 | 89.000 | COc1cc(NC(=O)C(N)CCCN=C(N)N)cc2ccccc12 | 100mg | 490843132
Medchemexpress LLC LY2389575 hydrochlor 5mg | 885104-09-6 | 5MG
LY2389575 hydrochloride is a selective and noncompetitive mGlu3 negative allosteric modulator (NAM) with an IC50 value of 190 nM LY2389575 hydrochloride induces an increase in Mrc1 levels LY2389575 hydrochloride also independently amplifies Amyloid beta (A ) toxicity and can be used in study of Alzheimer s disease[1 [2 [3