Hydrochlorides
Medchemexpress LLC L-778123 hydrochloride | 253863-00-2 | 99.9% | 442.34 | 50 MG
L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I, with IC50 values of 2 nM and 98 nM respectively. It is intended for research use only.
- Dual inhibitor of FPTase and GGPTase-I.
- Exhibits IC50 values of 2 nM for FPTase and 98 nM for GGPTase-I.
- Alone, it does not show obvious cytotoxicity on HT-29 and A549 cell lines (IC50: >100 μM), but can generate synergistic effects with Doxorubicin.
- Inhibits myeloid leukemia cell proliferation with IC50 values ranging from 0.2 μM to 1.8 μM for cell lines, and 0.1 μM to 161.8 μM in primary samples.
- Inhibits H-RAS prenylation in HL-60 cells and phosphorylated MEK-1/2 levels.
- Inhibits lymphocyte activation and function in human PBMCs.
Medchemexpress LLC TP0427736 hydrochloride | 2459963-17-6 | 99.2% | 334.85 | C14H11ClN4S2 | 5 MG
TP0427736 hydrochloride is a potent ALK5 (TGF-β receptor I) kinase inhibitor supplied as the hydrochloride salt for laboratory research use. It has reported biochemical potency (IC50 2.72 nM), a molecular weight of 334.85 g/mol, and a reported purity of 99.22%.
- Potent ALK5 kinase inhibitor (IC50 2.72 nM).
- Provided as hydrochloride salt to improve solubility for assays.
- High reported purity suitable for research applications.
- Available in small pack sizes for screening and assay development.
- Molecular weight 334.85 g/mol.
Medchemexpress LLC YM-298198 hydrochloride | 1216398-09-2 | MFCD08703122 | 98.0% | 378.92 g/mol | C18H23ClN4OS | 50 MG
YM-298198 hydrochloride is the hydrochloride salt of YM-298198, a selective, orally active, non-competitive antagonist of metabotropic glutamate receptor 1 (mGluR1). Supplied as a solid research-grade reagent, it is used in pharmacology studies and neurological disease models.
- Selective mGluR1 antagonist for receptor pharmacology studies.
- Orally active and non-competitive mechanism of action.
- Supplied as a solid hydrochloride salt for stability and handling.
- Molecular formula C18H23ClN4OS and molecular weight 378.92 g/mol.
- High purity suitable for research applications.
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 50 MG
T-3775440 hydrochloride is an irreversible inhibitor of lysine-specific histone demethylase 1 (LSD1) with low-nanomolar potency. It is provided as a high-purity research reagent for biochemical and cellular studies of epigenetic regulation.
- Irreversible LSD1 inhibition with an IC50 of ~2.1 nM.
- High chemical purity suitable for research use.
- Available in small-scale quantities for screening and mechanistic studies.
- Useful for biochemical assays and cellular models of epigenetic regulation.
- Provided as a hydrochloride salt to improve stability and solubility.
Medchemexpress LLC DANP dihydrochloride | 761401-89-2 | 99.3% | 100 MG
DANP dihydrochloride is a bulge base recognition probe that strongly and specifically binds to single cytosine and thymine bulges.
- Functions as a bulge base recognition probe
- Strongly and specifically binds to single cytosine and thymine bulges
- Can stabilize both single cytosine and thymine bulges in duplex DNA
Medchemexpress LLC uPSEM792 hydrochloride | 2341841-08-3 | 99.9% | 277.75 g/mol | C14H16ClN3O | 10 MG
uPSEM792 hydrochloride is an ultrapotent pharmacologically selective effector molecule (uPSEM) that acts as a high-affinity agonist for engineered PSAM4-GlyR receptors. It is provided for research use only and is commonly used in neuroscience experiments to selectively activate PSAM4-based receptors.
- High potency agonist for PSAM4-GlyR with reported Ki ≈ 0.7 nM.
- Suitable for in vitro and in vivo research applications.
- Supplied as the hydrochloride salt with high chemical purity.
- Available in small research-scale quantities for experimental use.
Apexbio Technology LLC Nitrocaramiphen hydrochloride 98636-73-8 10mg
Nitrocaramiphen hydrochloride (CAS 98636-73-8) is a small molecule that acts as a selective antagonist of muscarinic acetylcholine M1 receptors exhibiting a Ki of 5 5 nM Studies indicate that it effectively inhibits the hyperpolarizing effects induced by muscarinic agonists in muscle fibers Due to its receptor specificity nitrocaramiphen hydrochloride is widely utilized in neurobiological research to investigate cholinergic signaling pathways and the physiological roles of M1 receptor modulation
Medchemexpress LLC 2-(benzofuran-2-yl)-2-imidazoline hydrochloride | 89196-95-2 | MFCD00672666 | 99.8% | 222.67 g·mol⁻¹ | C11H11ClN2O | 100 MG
RX 801077 hydrochloride is a research chemical that functions as a selective imidazoline I2 receptor (I2R) agonist used in preclinical studies of inflammation and neuroprotection. It is supplied as the hydrochloride salt in small solid quantities or as DMSO solutions for biological assays.
- Selective imidazoline I2 receptor agonist (Ki ≈ 70.1 nM).
- High purity (99.8%) for reliable experimental results.
- Molecular weight 222.67 g·mol⁻¹ and CAS 89196-95-2 for unambiguous identification.
- Available as solid and 10 mM DMSO solution formats for assay preparation.
- Supplied in small research quantities suitable for in vitro studies.
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | 99.7% | 269.77 g·mol^-1 | C14H20ClNO2 | 100 MG
Piperoxan hydrochloride is a research chemical described as an α2 adrenoceptor antagonist and a first-generation antihistamine, provided for laboratory pharmacology and biochemical studies. Consult the product datasheet and safety data sheet for handling, storage, and purity specifications.
- High reported purity (about 99.7%).
- Available as a solid and as a 10 mM solution in DMSO.
- Suitable for pharmacology and biochemical research applications.
- CAS number provided for unambiguous identification.
- Manufacturer datasheet and SDS available for safety and handling.
eMolecules 1402576-61-7 | 7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | AstaTech | MFCD28133454 | 212.175 | C10H7F3N2 | 95.000 | Nc1cnc2cc(ccc2c1)C(F)(F)F | 1g | 261435877
7-(TRIFLUOROMETHYL)QUINOLIN-3-AMINE | AstaTech | 1402576-61-7 | MFCD28133454 | 212.175 | C10H7F3N2 | 95.000 | Nc1cnc2cc(ccc2c1)C(F)(F)F | 1g | 261435877
Cayman Chemical Terbinafine hydrochloride
A broad-spectrum antifungal agent; has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 μg/ml); selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 μM, respectively); induces cell cycle arrest at the G0/G1 phase in COLO 205 tumor cells and HUVECs from 90-120 μM
eMolecules 3332-29-4 | O-Ethylhydroxylamine hydrochloride | Chem-Impex | MFCD00012956 | 97.540 | C2H8ClNO | 99.000 | Cl.CCON | 1g | 112767804
O-Ethylhydroxylamine hydrochloride | Chem-Impex | 3332-29-4 | MFCD00012956 | 97.540 | C2H8ClNO | 99.000 | Cl.CCON | 1g | 112767804
![Medchemexpress LLC 3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride | 1197334-04-5 | 99.4% | 328.80 g/mol | C17H17ClN4O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000245959.png-250.jpg)
Medchemexpress LLC 3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride | 1197334-04-5 | 99.4% | 328.80 g/mol | C17H17ClN4O | 10 MG
SB 206553 hydrochloride is the hydrochloride salt of a selective 5-HT2B/5-HT2C serotonin receptor antagonist used in pharmacological research. It is supplied as a high-purity solid for in vitro and in vivo studies and is typically provided in small milligram pack sizes.
- Selective 5-HT2B and 5-HT2C receptor antagonist.
- High purity, 99.4%.
- Hydrochloride salt form for improved solubility.
- Supplied in small pack sizes suitable for research (e.g., 5 MG, 10 MG, 25 MG).
- Recommended storage: sealed, away from moisture; solid at -20°C; in solvent, -80°C for long-term.
Medchemexpress LLC Terbinafine | 91161-71-6 | MFCD00242672 | 99.96% | 291.43 | 500 MG
Terbinafine (TDT 067) is an orally active and potent antifungal agent. It is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also demonstrates antibacterial activity against certain Gram-positive and Gram-negative bacteria. It is a click chemistry reagent that contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Orally active.
- Potent antifungal agent.
- Potent non-competitive inhibitor of squalene epoxidase.
- Shows antibacterial activity against certain gram-positive and gram-negative bacteria.
- Click chemistry reagent.
- Contains an alkyne group.
- Can undergo copper-catalyzed azide-alkyne cycloaddition with molecules containing azide groups.
Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 g·mol⁻¹ | C4H8ClNS | 500 MG
2-Iminothiolane hydrochloride is a thiolation reagent that introduces free sulfhydryl (-SH) groups into primary amines on proteins, peptides, and oligosaccharides under mild aqueous conditions (pH 7-10). It is commonly used to generate thiol handles for downstream conjugation, crosslinking, and labeling workflows where efficient coupling to thiol-reactive probes is required.
- High purity suitable for biochemical applications.
- Introduces free sulfhydryl groups to primary amines at pH 7-10.
- Enables efficient conjugation to maleimide or thiol-reactive probes.
- Reactive under mild, aqueous conditions preserving biomolecule integrity.
- Available in multiple pack sizes for scale flexibility.