Hydrochlorides
Medchemexpress LLC Cyclopentanecarboxylic acid, 1-(4-nitrophenyl)-, 2-(diethylamino)ethyl ester, hydrochloride | 98636-73-8 | MFCD00673872 | 99.6% | 370.87 g/mol | C18H27ClN2O4 | 25 MG
Nitrocaramiphen hydrochloride is a selective M1 muscarinic receptor antagonist supplied as the hydrochloride salt for research use. It inhibits muscarine-induced hyperpolarization in muscle fibers and is provided as a white to off-white solid suitable for biochemical and pharmacological studies.
- Selective M1 receptor antagonist (Ki: 5.5 nM).
- High purity: 99.6% (manufacturer COA).
- White to off-white solid, molecular formula C18H27ClN2O4.
- Molecular weight 370.87 g/mol.
- Available in small milligram quantities for research use.
- Store sealed away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
Medchemexpress LLC Anabasine ((S)-Anabasine) | 494-52-0 | MFCD00006370 | 99.0% | 100 MG
Anabasine ((S)-Anabasine) is an alkaloid found as a minor component in tobacco. It functions as a botanical pesticide nicotine and acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). It induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs, with an EC50 of 0.7 μM. Studies show it significantly reverses impairment at 0.2 mg/kg and 2 mg/kg doses.
- Functions as a botanical pesticide nicotine
- Acts as a full agonist of nicotinic acetylcholine receptors (nAChRs)
- Induces depolarization of TE671 cells with an EC50 of 0.7 μM
- Significantly reverses impairment at 0.2 mg/kg and 2 mg/kg doses
- Does not significantly affect response latency when administered alone
- Exacerbates dizocilpine-induced impairment at 0.06 mg/kg dose
- Does not independently affect choice accuracy
Medchemexpress LLC L-368,899 hydrochloride | 160312-62-9 | 100.0% | 591.23 | 10 MG
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist. It has IC50s of 8.9 nM for rat uterus oxytocin receptor and 26 nM for human uterus oxytocin receptor. It is used as a tocolytic agent.
- Potent oxytocin receptor antagonist
- Selective action
- Orally bioavailable
- Non-peptide structure
- IC50s of 8.9 nM for rat uterus oxytocin receptor and 26 nM for human uterus oxytocin receptor
- Used as a tocolytic agent
- Soluble in DMSO (100 mg/mL)
- Soluble in H2O (5 mg/mL)
- Storage at 4°C sealed, away from moisture
- In solvent storage at -80°C for 2 years or -20°C for 1 year
Medchemexpress LLC ZM323881 (hydrochloride) | 193000-39-4 | 99.6% | 411.86 | 10 MG
ZM323881 (hydrochloride) | 193000-39-4 | 99.6% | 411.86 | 10 MG
Medchemexpress LLC 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrochloride | 62717-42-4 | MFCD00069248 | 99.5% | 291.77 g/mol | C16H18ClNO2 | 500MG
SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor used as a research reagent to study D1-mediated signaling. It is supplied as a solid (also available as a 10 mM solution in DMSO) with analytical-grade purity and intended for research use only.
- CAS number 62717-42-4.
- Chemical formula C16H18ClNO2.
- Molecular weight 291.77 g/mol.
- D1 receptor IC50 ~110 nM.
- Purity approximately 99.5%.
- Available as solid quantities including 500 mg and larger sizes.
- Provided for research use only; not for human or clinical use.
eMolecules 30796-90-8 | 2-Methylazepane Hydrochloride | 250mg
Ambeed | 222-Trimethylacetamide | 10g | 552727992 | A420019 | 754-10-9 | MFCD00008011 | 101.149 | C5H11NO
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Medchemexpress LLC PIM-447 dihydrochloride | 1820565-69-2 | MFCD30489747 | 99.3% | 513.38 | C24H25Cl2F3N4O | 10 MG
PIM-447 dihydrochloride is the dihydrochloride salt of a potent, orally available pan-PIM kinase inhibitor used in preclinical research. It modulates apoptosis and JAK/STAT signaling and has been investigated for antimyeloma and bone-protective effects. This reagent is supplied for laboratory research use only.
- Potent pan-PIM kinase inhibition with low picomolar Ki values.
- Demonstrated antimyeloma and bone-protective activity in preclinical studies.
- High solubility in water and DMSO (H2O: 50 mg/mL; DMSO: ≥46.7 mg/mL).
- High purity (≈99.3%).
- Provided as a 10 mg solid suitable for preparing concentrated stock solutions.
- Stability supported by recommended storage conditions in solvent (-80°C 1 year; -20°C 6 months).
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC Dasatinib hydrochloride | 854001-07-3 | 99.3% | 524.47 g/mol | C22H27Cl2N7O2S | 500 MG
Dasatinib hydrochloride is the hydrochloride salt of dasatinib, a potent ATP-competitive dual Src/Bcr-Abl kinase inhibitor used in cancer research and cell signaling studies. It is supplied as a high-purity research reagent intended for in vitro and in vivo kinase inhibition assays and related biochemical applications.
- Potent ATP-competitive inhibitor of Src and Bcr-Abl kinases.
- Suitable for in vitro and in vivo research applications.
- Hydrochloride salt for improved solubility and handling.
- High purity (99.31% by HPLC) for reliable experimental results.
- Molecular formula C22H27Cl2N7O2S; molecular weight 524.47 g/mol.
- Available in a 500 mg research package.
eMolecules 21987-29-1 | 4,4-Difluoropiperidine | ChemScene | MFCD03094281 | 121.131 | C5H9F2N | 97.000 | FC1(F)CCNCC1 | 25g | 582633737
4,4-Difluoropiperidine | ChemScene | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 97.000 | FC1(F)CCNCC1 | 25g | 582633737
Medchemexpress LLC AQ-13 dihydrochloride | 169815-40-1 | MFCD01938526 | 98.1% | 364.74 g/mol | C16H24Cl3N3 | 10 MG
AQ-13 dihydrochloride is an aminoquinoline-class antimalarial research compound supplied as the dihydrochloride salt. It is used primarily in in vitro studies against drug-resistant Plasmodium falciparum and in investigations of aminoquinoline mechanism of action and resistance.
Medchemexpress LLC 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride | 1123491-15-5 | 99.1% | 339.22 | 10 MG
DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC50 of 80 nM. It is for research use only and not sold to patients.
- Potent and selective inhibitor of human PDGFRβ.
Medchemexpress LLC L-368,899 hydrochloride | 160312-62-9 | 99.9% | 591.23 | 25 MG
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist. It is used as a tocolytic agent and shows less activity on VP receptors in human and rat liver and kidney.
- Potent, orally bioavailable, non-peptide oxytocin receptor antagonist
- IC50s of 8.9 nM for rat uterus oxytocin receptor
- IC50s of 26 nM for human uterus oxytocin receptor
- Used as a tocolytic agent
- Less active on VP receptor in human and rat liver and kidney
- Exhibits similar pharmacokinetics in rats and dogs
- Orally available with demonstrated bioavailability in rats