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Filtered Search Results
Medchemexpress LLC Co 101244 hydrochloride | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 10 MG
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Co 101244 hydrochloride (PD 174494 hydrochloride) is a selective antagonist of NR2B (GluN2B)-containing NMDA receptors used to study NMDA receptor pharmacology and neuronal signaling in vitro. The hydrochloride salt is characterized by formula C21H28ClNO3, molecular weight 377.90 g/mol, and supplier-reported purity near 99.9%. It is supplied in small-molecule formats for research assays.
- Selective antagonist of NR2B-containing NMDA receptors.
- High chemical purity for reproducible experimental results.
- Hydrochloride salt form for improved solubility in assay solvents.
- Suitable for in vitro pharmacology and receptor binding assays.
- Available in mg-scale solid and DMSO solution formats.
- Molecular weight and formula provided for dosing calculations.
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eMolecules 1181556-77-3 | 1,2-Ethanediamine, N,N-dimethyl-N'-(tetrahydro-1,1-dioxido-3-thienyl)-, dihydrochloride | Combi-Blocks, Inc. | MFCD06682713 | 279.220 | C8H20Cl2N2O2S | 95.000 | Cl.Cl.CN(C)CCNC1CCS(=O)(=O)C1 | 1g | 586076681
1,2-Ethanediamine, N,N-dimethyl-N'-(tetrahydro-1,1-dioxido-3-thienyl)-, dihydrochloride | Combi-Blocks, Inc. | 1181556-77-3 | MFCD06682713 | 279.220 | C8H20Cl2N2O2S | 95.000 | Cl.Cl.CN(C)CCNC1CCS(=O)(=O)C1 | 1g | 586076681
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Medchemexpress LLC Erlotinib hydrochloride | 183319-69-9 | 99.7% | 25 MG
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Erlotinib hydrochloride analytical standard, the hydrochloride salt of erlotinib, provided as a high-purity solid for use as a reference material in biochemical and analytical assays.
- Analytical standard for erlotinib hydrochloride.
- Purity 99.73% (analytical).
- Molecular weight 429.90 g/mol.
- Chemical formula C22H24ClN3O4.
- Appearance: white to off-white solid.
- Available sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg; 200 mg and 500 mg available by quote.
- Store under conditions specified on the certificate of analysis.
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Apexbio Technology LLC Terbinafine 91161-71-6 200mg
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Terbinafine is an allylamine-class antifungal that exerts fungicidal effects by selectively inhibiting fungal squalene epoxidase thereby disrupting ergosterol biosynthesis and altering fungal cell membrane integrity Research demonstrates Terbinafine s broad-spectrum activity against diverse dermatophytes molds and select dimorphic fungal pathogens with in vitro IC50 values generally ranging from approximately 0 001 to 0 06 g/mL dependent on fungal strain and experimental condition In biological and biomedical studies Terbinafine is frequently employed as a pharmacological tool to probe antifungal mechanisms screen fungal susceptibility profiles and investigate therapeutic strategies against fungal infections
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Medchemexpress LLC VU0360172 hydrochloride | 1309976-62-2 | 98.9% | 330.78 | C18H16ClFN2O | 5 MG
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VU0360172 hydrochloride is a potent, selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5). It potentiates mGlu5 signaling (EC50 = 16 nM; Ki = 195 nM) and is supplied as a white to off-white solid for research use. Typical applications include receptor pharmacology, cellular signaling assays, and in vivo pharmacology studies.
- Potent mGlu5 PAM activity (EC50 16 nM).
- Confirmed binding affinity (Ki 195 nM).
- High purity suitable for research (98.9%).
- Molecular weight 330.78 for accurate dosing and calculations.
- Solid form, white to off-white, for convenient handling and storage.
- Recommended storage: store sealed at -20°C; in solution, -80°C for long term.
- Supplied in small research pack sizes appropriate for pilot studies.
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Medchemexpress LLC DRP1i27 dihydrochloride | C20H28Cl2N6O | 5 MG
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DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1
- Increases cellular networks of mitochondria in human and mouse fibroblasts
- Protective effects against simulated ischemia-reperfusion injury
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eMolecules 51285-26-8 | Picolinimidamide hydrochloride | ChemScene | MFCD00052271 | 157.600 | C6H8ClN3 | 95.000 | Cl.NC(=N)c1ccccn1 | 5g | 789369249
Picolinimidamide hydrochloride | ChemScene | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 95.000 | Cl.NC(=N)c1ccccn1 | 5g | 789369249
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Medchemexpress LLC Etazolate hydrochloride | 35838-58-5 | MFCD00209848 | 98.0% | 325.79 | C14H20ClN5O2 | 50 MG
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Etazolate hydrochloride is the hydrochloride salt of etazolate, a pyrazolopyridine-derived small molecule used in research as a selective phosphodiesterase-4 (PDE4) inhibitor and a GABAA receptor modulator. It is provided as a high-purity research reagent intended for in vitro and in vivo studies investigating neurological function, inflammation, and related signaling pathways.
- High-purity hydrochloride salt suitable for research use.
- Selective phosphodiesterase-4 (PDE4) inhibition activity.
- Modulates GABAA receptor function.
- Supplied in a convenient small-scale pack for laboratory studies.
- Characterized by molecular formula and molecular weight for traceability.
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Med Vet International Terbinafine Hydrochloride, 250mg Tablets, 30 Count
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Terbinafine Hydrochloride, 250mg Tablets, 30 Count
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Medchemexpress LLC Ecopipam (hydrochloride) | 190133-94-9 | 99.5% | 350.28 | 1 ML
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Ecopipam hydrochloride is a potent and selective antagonist of dopamine D1/D5 receptors. It demonstrates significant selectivity over D2, D4, 5-HT, and α2a receptors. This compound is suitable for research into conditions such as schizophrenia and obesity.
- Potent and selective dopamine D1/D5 receptor antagonist
- Exhibits over 40-fold selectivity for D1/D5 over D2, D4, 5-HT, and α2a receptors
- Suitable for research applications in schizophrenia and obesity
- High purity of 99.46%
- Appears as a white to off-white solid
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Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 99.9% | 260.72 g/mol | C11H17ClN2O3 | 10 MG
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Nifenalol hydrochloride is a β-adrenergic receptor antagonist used in pharmacological research. It is supplied as a solid and as a pre-made DMSO solution for convenient dosing and assay preparation, and is commonly used in biochemical and electrophysiological studies of β-adrenoceptor activity.
- High purity (99.9%) suitable for biochemical and cellular assays.
- Available in small solid quantities and as 10 mM solutions in DMSO for convenience.
- Supports studies of β-adrenergic receptor antagonism and early afterdepolarization effects.
- Characterized by CAS number 5704-60-9 and standard chemical identifiers.
- Supplied for research use with accompanying datasheet information for handling.
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Medchemexpress LLC Prodipine hydrochloride | 31314-39-3 | 99.8% | 315.88 g/mol | C20H26ClN | 5 MG
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Prodipine hydrochloride is a diphenyl-phosphonate derivative that acts as a dipeptidyl peptidase IV (DPP-IV) inhibitor. Supplied as the hydrochloride salt for research use, it is intended for enzymology, inhibitor screening, and preclinical biochemical assays; reported IC50 values are ~4.5 μM (purified rabbit DPP-IV) and ~30 μM (rabbit plasma).
- Potent DPP-IV inhibitory activity in vitro.
- Supplied as hydrochloride salt for improved solubility.
- High purity suitable for biochemical assays.
- Available in small milligram pack sizes for screening.
- Characterized with reported IC50 data for assay comparison.
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Medchemexpress LLC Gaboxadol hydrochloride | 85118-33-8 | MFCD00055180 | 99.9% | 176.60 g/mol | C6H9ClN2O2 | 5 MG
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Gaboxadol hydrochloride is a small-molecule GABAA receptor agonist used in neuroscience and pharmacology research. Supplied as a solid with high reported purity, it is intended for in vitro and in vivo experimental studies.
- High purity for research applications.
- Solid form suitable for accurate weighing and formulation.
- Active at GABAA receptors; useful for GABAergic pharmacology studies.
- Stable under recommended storage conditions (sealed, away from moisture and light).
- Small quantity packaging suitable for experimental use.
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eMolecules 127168-84-7 | AstaTech | 5-BROMOISOINDOLINE | 0.25g | 222807976 | AB3161 | 95 | MFCD08234718 | 198.063 | C8H8BrN
Ambeed | 4-Fluoro-26-dimethylbenzonitrile | 100mg | 633419216 | A833849 | 14659-61-1 | MFCD04972839 | 149.168 | C9H8FN
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Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 50 MG
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VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with an EC50 of 19.8 nM. Intended for research use only, this solid compound appears white to off-white. While it demonstrates better stability in Human Liver Microsomes, its less than ideal PK properties prevent its use as an in vivo tool.
- Positive allosteric modulator (PAM) for mGlu4
- EC50 of 19.8 nM
- Purity of 99.42%
- Solid appearance, white to off-white color
- Exhibits better stability in HLM (63% remaining) compared to RLM (2% remaining)
- Target: mGluR
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