Hydrochlorides
Medchemexpress LLC Ly2389575 hydrochloride | 885104-09-6 | 99.9% | 438.58 | C15H16BrCl3N4 | 1 ML
LY2389575 hydrochloride is a selective, noncompetitive negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3), supplied as a 10 mM solution in DMSO for research use. The compound is reported with high purity and recommended storage conditions for powder and solution forms.
- Selective, noncompetitive mGlu3 negative allosteric modulator.
- Provided as a 10 mM solution in DMSO, 1 mL volume.
- High reported purity suitable for in vitro research applications.
- Recommended storage conditions specified for powder and solution forms.
- Useful for studies of glutamatergic signaling and disease-related pathways.
Medchemexpress LLC Iptakalim hydrochloride | 642407-63-4 | 98.0% | 179.73 g/mol | C9H22ClN | 10 MG
Iptakalim hydrochloride is a lipophilic para-amino small molecule used in research as an ATP-sensitive potassium (KATP) channel opener and α4β2-containing nicotinic acetylcholine receptor modulator. It is supplied as the hydrochloride salt for laboratory pharmacology and formulation studies.
- Acts as an ATP-sensitive potassium (KATP) channel opener and α4β2-containing nicotinic receptor modulator.
- CAS number 642407-63-4.
- Molecular formula C9H22ClN; molecular weight 179.73 g/mol.
- Purity 98.0%.
- Available in milligram pack sizes for research, including 10 mg.
- Solubility: water 25 mg/mL (requires warming and sonication); PBS formulations achievable.
- Storage: solid sealed at 4°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC RS-25344 hydrochloride | 152815-28-6 | 99.9% | 411.80 | 10 MM/1 ML
RS-25344 hydrochloride | 152815-28-6 | 99.9% | 411.80 | 10 MM/1 ML
Medchemexpress LLC DRP1i27 dihydrochloride | 1453028-33-5 | C20H28Cl2N6O | 100 MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1 (0-50 μM).
- Increases cellular networks of mitochondria in human and mouse fibroblasts in a Drp1-dependent manner.
- Exhibits a binding affinity of 286 μM in the SPR assay and a KD value of 190 μM via the MST assay.
Medchemexpress LLC Pazopanib hydrochloride | 635702-64-6 | 100.0% | 50 MG
Pazopanib hydrochloride is the hydrochloride salt of pazopanib, a small-molecule multi-target tyrosine kinase inhibitor active against VEGFR1/2/3, PDGFRβ, c-Kit, and FGFR1. It is supplied as a research reagent for in vitro pharmacology, cell-based assays, and preclinical studies.
- High purity suitable for research applications.
- Available as solid and DMSO solution formats for flexible use.
- Useful for kinase inhibition, cell signaling, and oncology research.
- Offered in multiple pack sizes to support screening and preclinical work.
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 50 MG
T-3775440 hydrochloride is an irreversible inhibitor of lysine-specific histone demethylase 1 (LSD1) with low-nanomolar potency. It is provided as a high-purity research reagent for biochemical and cellular studies of epigenetic regulation.
- Irreversible LSD1 inhibition with an IC50 of ~2.1 nM.
- High chemical purity suitable for research use.
- Available in small-scale quantities for screening and mechanistic studies.
- Useful for biochemical assays and cellular models of epigenetic regulation.
- Provided as a hydrochloride salt to improve stability and solubility.
Medchemexpress LLC Doxapram (hydrochloride hydrate) | 7081-53-0 | 99.3% | 1 ML
Doxapram hydrochloride hydrate is a respiratory stimulant that increases breathing rate and depth by acting on the brain's respiratory centers and peripheral chemoreceptors. It can be used for the study of respiratory depression such as post-anesthesia respiratory depression, chronic obstructive pulmonary disease, and apnea of prematurity.
- Inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channel function
- Inhibits Ca²⁺-activated and Ca²⁺-independent potassium current in type I cells of the carotid body
- Significantly prolongs the effective refractory period of the atrium
- Has an anti-arrhythmic effect
eMolecules 167465-93-2 | 4-Aminopyrrolidin-2-one hydrochloride | MFCD11519397 | 1g
Ambeed | (2E6E10E)-371115-Tetramethylhexadeca-261014-tetraen-1-ol | 250mg | 572143834 | A682516 | 24034-73-9 | MFCD00129083 | 290.491 | C20H34O
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Medchemexpress LLC 2-(benzofuran-2-yl)-2-imidazoline hydrochloride | 89196-95-2 | MFCD00672666 | >=98.0% | 222.67 g/mol | C11H11ClN2O | 25 MG
RX 801077 hydrochloride (2-BFI) is a research compound that acts as a selective imidazoline I2 receptor (I2R) agonist. It is used in preclinical studies for its reported anti-inflammatory and neuroprotective effects and is suitable for investigations into traumatic brain injury and related neurobiology.
- Selective imidazoline I2 receptor agonist with a reported Ki of ≈70.1 nM.
- Demonstrates anti-inflammatory and neuroprotective activity in preclinical models.
- Supplied as a hydrochloride salt for improved stability and handling.
- High purity suitable for analytical and exploratory studies (≥98%).
- Well-characterized chemical data: C11H11ClN2O, molecular weight 222.67 g/mol, CAS 89196-95-2.
- Available in small-scale quantities appropriate for laboratory research.
Medchemexpress LLC uPSEM792 hydrochloride | 2341841-08-3 | 99.9% | 277.75 g/mol | C14H16ClN3O | 10 MG
uPSEM792 hydrochloride is an ultrapotent pharmacologically selective effector molecule (uPSEM) that acts as a high-affinity agonist for engineered PSAM4-GlyR receptors. It is provided for research use only and is commonly used in neuroscience experiments to selectively activate PSAM4-based receptors.
- High potency agonist for PSAM4-GlyR with reported Ki ≈ 0.7 nM.
- Suitable for in vitro and in vivo research applications.
- Supplied as the hydrochloride salt with high chemical purity.
- Available in small research-scale quantities for experimental use.
Medchemexpress LLC ZT 52656A hydrochloride | 115730-24-0 | 100.0% | 390.87 g/mol | C19H26ClF3N2O | 1 MG
ZT 52656A hydrochloride is the hydrochloride salt of a selective kappa opioid receptor agonist supplied for laboratory research. It is used to investigate kappa-mediated analgesia, including prevention or alleviation of ocular pain, and is intended for preclinical in vitro and in vivo studies. Not for human or clinical use.
- Selective kappa opioid receptor agonist.
- Used in ocular pain models to assess analgesic effects.
- High purity (99.98%) suitable for research applications.
- Solid, white to off-white physical form.
- Hydrochloride salt for improved stability and solubility.
- Available in small research pack sizes for preclinical work.
![Medchemexpress LLC 3,6-diazabicyclo[3.2.2]nonane, 3-[(4-methyl-1h-imidazol-5-yl)methyl] (dihydrochloride) | 1453028-33-5 | 98.6% | 439.38 g/mol | C20H28Cl2N6O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286113.png-250.jpg)
Medchemexpress LLC 3,6-diazabicyclo[3.2.2]nonane, 3-[(4-methyl-1h-imidazol-5-yl)methyl] (dihydrochloride) | 1453028-33-5 | 98.6% | 439.38 g/mol | C20H28Cl2N6O | 10 MG
DRP1i27 dihydrochloride is a research-grade small-molecule inhibitor of dynamin-related protein 1 (Drp1), provided as the dihydrochloride salt for laboratory studies of mitochondrial fission and related cellular processes.
- Potent inhibitor of Drp1 GTPase activity demonstrated in cell models.
- Supplied as a dihydrochloride salt suitable for biochemical and cellular assays.
- Available in multiple quantities and formats, including solid and 10 mM DMSO solutions.
- High purity: 98.6% (reported by manufacturer).
- Molecular formula C20H28Cl2N6O; molecular weight 439.38 g/mol.
- Documentation available: datasheet, COA, SDS, and spectral data for QC support.
Medchemexpress LLC Erlotinib hydrochloride | 183319-69-9 | 50MG
Erlotinib hydrochloride | 183319-69-9 | 50MG
Medchemexpress LLC Queuine dihydrochloride | 86496-18-6 | 350.20 | 25 MG
Queuine dihydrochloride | 86496-18-6 | 350.20 | 25 MG