Hydrochlorides
Medchemexpress LLC BRL 52537 hydrochloride | 112282-24-3 | 98.1% | 391.76 | C18H25Cl3N2O | 25 MG
BRL 52537 hydrochloride is a selective κ-opioid receptor (KOR) agonist supplied as the hydrochloride salt for research use. It is commonly used in pharmacology and neuroscience studies to probe KOR-mediated signaling and investigate neuroprotective effects; the compound is provided with reported high purity suitable for preclinical laboratory experiments.
- Selective κ-opioid receptor agonist with high affinity.
- Supplied as the hydrochloride salt for research use.
- High reported purity suitable for laboratory experiments.
- Available in small pre-weighed quantities for convenient dosing.
- Used in pharmacology and neuroprotection research models.
Medchemexpress LLC 2-(1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole hydrochloride | 89196-95-2 | MFCD00672666 | >=98.0% | 222.67 g/mol | C11H11ClN2O | 5 MG
RX 801077 hydrochloride (2-BFI) is a research-grade imidazoline I2 receptor (I2R) agonist used in preclinical and in vitro studies to investigate neuroprotective and anti-inflammatory effects. The hydrochloride salt is supplied as a solid and as solution formulations for laboratory use.
- Selective imidazoline I2 receptor agonist with reported Ki ≈ 70.1 nM.
- Demonstrates anti-inflammatory and neuroprotective activity in preclinical studies.
- Available as solid and as 10 mM solution in DMSO.
- Supplied in multiple laboratory pack sizes, including 5 mg.
- Molecular weight 222.67 g/mol.
- CAS number 89196-95-2.
- Purity ≥98% by HPLC.
Apexbio Technology LLC Dapoxetine HCl 129938-20-1 50mg
Dapoxetine hydrochloride (CAS 129938-20-1) is a short-acting selective serotonin reuptake inhibitor (SSRI) It exerts its pharmacological effect by inhibiting the reuptake of serotonin (5-HT) at the presynaptic membrane thereby increasing serotonin activity in the synaptic cleft This modulation of serotonergic neurotransmission has been shown to delay ejaculation latency making dapoxetine hydrochloride an established model compound for investigating serotonergic regulation of ejaculatory control It is widely used in research on the neurobiology and therapeutic approaches to premature ejaculation and related disorders
Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 99.9% | 260.72 | C11H17ClN2O3 | 50 MG
Nifenalol hydrochloride is the hydrochloride salt of a β-adrenergic receptor antagonist used in cardiovascular and receptor pharmacology research. It is provided as a high-purity solid reagent with supporting analytical documentation for laboratory use.
- High purity for reliable experimental results.
- Hydrochloride salt, stable solid form for storage and handling.
- Suitable for in vitro adrenergic receptor assays and cardiovascular studies.
- Certificate of analysis and safety data sheet available for quality and safety documentation.
- Available in small research pack sizes for laboratory workflows.
![Medchemexpress LLC (S)-9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoind | 2092923-21-0 | 99.5% | 438.85 | C24H17ClF2N2O2 | 10 MM 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211664.png-250.jpg)
Medchemexpress LLC (S)-9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoind | 2092923-21-0 | 99.5% | 438.85 | C24H17ClF2N2O2 | 10 MM 1 ML
VU 6008667 is a selective negative allosteric modulator of the muscarinic acetylcholine receptor M5. It inhibits human M5 and rat M5 with IC50 values of 1.2 μM and 1.6 μM, respectively, and is supplied for research use only as a 10 mM solution in DMSO (1 mL); solid quantities are also available. Reported data indicate high central nervous system penetration.
- Selective M5 negative allosteric modulator with documented IC50 values.
- High central nervous system penetration suitable for CNS studies.
- Provided as a ready-to-use 10 mM solution in DMSO (1 mL).
- High purity with supporting analytical documentation (COA, HPLC, MS).
- Intended for research use only; not for clinical or therapeutic use.
Medchemexpress LLC Benzamide, 4-butoxy-N-(2,4-difluorophenyl)- | 433967-28-3 | C17H17F2NO2 | 5 MG
VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC50 of 33 nM. It is inactive or very weakly antagonizing at other mGlu receptor subtypes, enhancing glutamate sensitivity of mGlu5 likely due to interaction at a site on the receptor distinct from the MPEP binding site.
- Positive and highly selective mGlu5R allosteric modulator
- EC50 of 33 nM for mGlu5 receptor
- Inactive or very weakly antagonizing at other mGlu receptor subtypes
- Enhances glutamate sensitivity of mGlu5
- Does not bind at the MPEP allosteric site of mGlu5
eMolecules 16179-97-8 | 2-Pyridylacetic acid hydrochloride | Combi-Blocks | MFCD00012812 | 173.600 | C7H8ClNO2 | 97.000 | Cl.OC(=O)Cc1ccccn1 | 5g | 232307884
2-Pyridylacetic acid hydrochloride | Combi-Blocks | 16179-97-8 | MFCD00012812 | 173.600 | C7H8ClNO2 | 97.000 | Cl.OC(=O)Cc1ccccn1 | 5g | 232307884
Medchemexpress LLC Iso-H7 dihydrochloride | 140663-38-3 | 99.1% | 364.29 | 1 MG
Iso-H7 dihydrochloride is a protein kinase inhibitor. It exhibits IC50 values of 22 μM for Protein Kinase C (PKC) and 34 μM for Protein Kinase A (PKA). This compound has been observed to have a negative control effect on PKA in the context of satellite cell myogenesis.
- Potent inhibitor of protein kinases, specifically PKC and PKA.
- Demonstrates inhibitory activity against PKC with an IC50 of 22 μM.
- Inhibits PKA with an IC50 of 34 μM.
- Exerts negative control over PKA's role in satellite cell myogenesis.
- Suitable for research applications.
Medchemexpress LLC Terbinafine hydrochloride | 78628-80-5 | 99.9% | 327.89 | 1 ML
Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. It acts as a non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. This compound also exhibits antibacterial activity against certain Gram-positive and Gram-negative bacteria. Furthermore, it is a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.
- Primarily shows fungicidal action against most fungal pathogens, including dermatophytes, dimorphic, and filamentous fungi.
- Specifically inhibits fungal ergosterol biosynthesis by blocking squalene epoxidation.
- Leads to rapid accumulation of squalene and a deficiency of ergosterol in treated fungal cells.
- Effective in experimental dermatophytoses following oral administration and topical application.
Medchemexpress LLC Tirofiban (hydrochloride monohydrate) | 150915-40-5 | 99.9% | 495.07 | 1 ML
Tirofiban (hydrochloride monohydrate) | 150915-40-5 | 99.9% | 495.07 | 1 ML