Hydrochlorides
Medchemexpress LLC Bestatin hydrochloride | 65391-42-6 | 99.94% | 5 MG
Bestatin hydrochloride is a chemical compound known for its role as a competitive inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase. It is utilized in cancer research and is available with a high purity of 99.94%. This product is intended for research use only.
- Inhibitor of CD13 (Aminopeptidase N)/APN
- Inhibitor of leukotriene A4 hydrolase
- Used for cancer research
- Enhances ATRA-induced differentiation
- Inhibits ATRA-driven phosphorylation of p38 MAPK
- Solid, white to off-white appearance
- Store at 4°C under nitrogen
Sigma Aldrich Fine Chemicals Biosciences o-Phenylenediamine dihydrochloride tablet, 3 mg substrate per tablet | 615-28-1 | MFCD00012966 | 50TAB
o-Phenylenediamine dihydrochloride tablet, 3 mg substrate per tablet | Mol Wt: 181.06 | 615-28-1 | MFCD00012966 | 50TAB
![Medchemexpress LLC N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)benzamide hydrochloride | 495076-64-7 | 99.9% | 448.98 g/mol | C24H33ClN2O4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240661.png-250.jpg)
Medchemexpress LLC N-[[1-(dimethylamino)cyclopentyl]methyl]-3,5-dimethoxy-4-(phenylmethoxy)benzamide hydrochloride | 495076-64-7 | 99.9% | 448.98 g/mol | C24H33ClN2O4 | 5 MG
Org 25543 hydrochloride is the hydrochloride salt of a selective and irreversible glycine transporter 2 (GlyT2) inhibitor (IC50 16 nM) used as a research reagent to study glycine transport and analgesic mechanisms in preclinical models. It is supplied as a solid, high-purity material and should be stored sealed at -20°C to preserve stability.
- Selective GlyT2 inhibition (IC50 16 nM).
- Demonstrated analgesic activity in rodent neuropathic pain models.
- High purity (>99.9%).
- Solid form suitable for formulation and dosing in preclinical work.
- Recommended storage at -20°C, sealed and protected from moisture.
- Available in small research quantities for screening and pharmacology studies.
Medchemexpress LLC Vasicine (hydrochloride) | 7174-27-8 | 98.6% | 224.69 | 5 MG
Vasicine hydrochloride is a quinazoline alkaloid isolated from *Justicia adhatoda*. It activates the PI3K/Akt signaling pathway, demonstrating antioxidant, anti-inflammatory, and antibacterial properties. In vitro studies show it inhibits H+/K+-ATPase, scavenges DPPH free radicals, reduces gastric acid secretion, and has anti-ulcer effects. In vivo, it improves cardiac function, inhibits myocardial cell apoptosis, and alleviates myocardial damage and inflammation.
- Inhibits H+/K+-ATPase and scavenges DPPH free radicals
- Reduces gastric acid secretion; provides anti-ulcer effects
- Improves cardiac function and inhibits myocardial cell apoptosis
- Alleviates myocardial necrosis, edema, and inflammatory cell infiltration
- Reduces LDH and CK-MB levels
- Increases LVSP and myocardial contractility
- Lowers TNF-α and IL-6 levels
- Increases SOD and GPx activities in myocardial tissue
Medchemexpress LLC GKT136901 hydrochloride | 1254507-01-1 | 99.9% | 403.26 g/mol | C19H16Cl2N4O2 | 1 ML
GKT136901 hydrochloride is a research-grade small-molecule inhibitor selective for NADPH oxidase isoforms NOX1 and NOX4. It is used in preclinical studies to investigate oxidative stress, inflammation, and related disease models such as diabetic nephropathy, stroke, and neurodegeneration. The hydrochloride salt is supplied as a solid or as a 10 mM solution in DMSO for biochemical and cell-based assays.
- Selective NOX1/4 inhibition for targeted research applications.
- Potent activity (Ki ≈ 160 nM) for effective pathway modulation.
- Available as a 10 mM solution in DMSO for ready-to-use assays.
- High chemical purity to support reproducible results.
- Supplied as a stable solid with recommended cold storage.
- Suitable for biochemical and cell-based experimental workflows.
Medchemexpress LLC Melflufen (hydrochloride) | 380449-54-7 | 98.1% | 534.88 | C24H31Cl3FN3O3 | 25 MG
Melflufen hydrochloride is a peptide-conjugated alkylating prodrug of melphalan supplied as a hydrochloride salt for research use. It demonstrates antitumor activity in preclinical studies, is provided as a high-purity solid for in vitro and biochemical oncology research, and should be handled according to the manufacturer safety data sheet.
- Peptide-conjugated alkylating prodrug.
- Demonstrates antitumor activity against multiple myeloma cells.
- Off-white to light yellow solid appearance.
- Purity approximately 98.06%.
- Molecular weight 534.88 g/mol.
- Available in small milligram pack sizes for research use.
- Store sealed at 4°C and protect from moisture; follow SDS for details.
Medchemexpress LLC preQ1 dihydrochlorid 25mg | 86694-45-3 | 252.10 g/mol | C7H11Cl2N5O | 25 MG
preQ1 dihydrochloride is the dihydrochloride salt of pre-queuosine1, a guanine-derived nucleobase and a direct precursor in queuine biosynthesis. It is supplied for research use as a biochemical probe that binds with high affinity to the PreQ1 riboswitch aptamer and is suitable for studies of tRNA modification and riboswitch function.
- High purity suitable for research use (98.88%).
- Solid, white to light brown appearance for easy handling.
- Soluble in DMSO (125 mg/mL) and water (14.29 mg/mL) with sonication or warming.
- Direct precursor in queuine biosynthesis and riboswitch-binding probe.
- Stable when stored sealed away from moisture and light; in solvent -80°C (6 months), -20°C (1 month).
Medchemexpress LLC 3-Pyridineacetic acid | 501-81-5 | 137.14 | 25 G
3-Pyridineacetic acid is an endogenous metabolite and a higher homologue of nicotinic acid. It is identified as a breakdown product of nicotine and other tobacco alkaloids.
- Formula: C7H7NO2
- Appearance: Solid, typically white to off-white
- Structure classification: Ketones, aldehydes, acids
- Potential application: Research on the metabolism of nicotine and tobacco alkaloids.
Cayman Chemical Terbinafine hydrochloride
A broad-spectrum antifungal agent; has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 μg/ml); selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 μM, respectively); induces cell cycle arrest at the G0/G1 phase in COLO 205 tumor cells and HUVECs from 90-120 μM
Medchemexpress LLC Tirofiban | 144494-65-5 | 440.60 | 5 MG
Tirofiban is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist. It inhibits fibrinogen binding to this receptor, providing antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cells by stimulating VEGF production. It can significantly reduce myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
- Selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist
- Inhibits fibrinogen binding
- Provides antithrombotic activity
- Induces endothelial cell proliferation and migration
- Stimulates vascular endothelial growth factor (VEGF) production
- Reduces myocardial no-reflow
- Alleviates myocardial microvascular structural and endothelial dysfunction
- Targets integrin
- Affects cytoskeleton pathway