Hydrochlorides
TARGETMOL CHEMICALS INC Terbinafine hydrochloride 1G
Also available in 1 mL, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes. Purity 99.89%
Medchemexpress LLC Bepridil hydrochloride hydrate | 74764-40-2 | 99.9% | 421.02 | 1 ML
Bepridil hydrochloride hydrate is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor. It possesses antianginal and type I antiarrhythmic effects and functions as a cardiac Na+/Ca2+ exchange (NCX1) inhibitor. It can be used for the research of cardiovascular disorders.
- Blocks Ca2+-dependent action potentials in vascular smooth muscle.
- Inhibits Ca currents and Na currents in cultured ventricular cells.
- Decreases IKs under blockade of IKr.
- Suitable for research into cardiovascular disorders.
Medchemexpress LLC Vasicine (hydrochloride) | 7174-27-8 | 224.69 | 1 ML
Vasicine hydrochloride is a quinazoline alkaloid isolated from Justicia adhatoda. It activates the PI3K/Akt signaling pathway and exhibits antioxidant, anti-inflammatory, and antibacterial activities. This product is for research use only.
- Activates the PI3K/Akt signaling pathway.
- Exhibits antioxidant, anti-inflammatory, and antibacterial activities.
- Shows moderate inhibitory activity against H+/K+-ATPase.
- Scavenges DPPH free radicals.
- Reduces gastric acid secretion and has an anti-ulcer effect.
- Improves cardiac function and inhibits myocardial cell apoptosis.
- Alleviates myocardial necrosis, edema, and inflammatory cell infiltration.
Medchemexpress LLC Carteolol hydrochloride | 51781-21-6 | 99.8% | 328.83 | 25 MG
Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma. For research use only. We do not sell to patients. Carteolol HCl is a beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
- Significantly inhibited H2O2-induced cell damage at 1 mmol/L (P<0.05) and scavenged O2 (EC50 value: 48 mmol/L).
- Exhibits protective action against UVB-induced HCEC damage, possibly due to its radical scavenging ability.
- A new alginate formulation of long-acting carteolol 1% given once daily is as effective as standard 1% carteolol given twice daily for glaucoma treatment, with comparable safety.
Medchemexpress LLC EG01377 dihydrochloride | 2749438-61-5 | 99.0% | 659.60 | 25 MG
EG01377 dihydrochloride is a potent, bioavailable, and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. It exhibits antiangiogenic, antimigratory, and antitumor effects by inhibiting vascular endothelial growth factor A (VEGF-A) stimulated tyrosine phosphorylation of VEGF-R2/KDR.
- Inhibits VEGF-A stimulated tyrosine phosphorylation of VEGF-R2/KDR.
- Reduces HUVEC cell migration and delays VEGF-induced wound closure.
- Reduces network area, length, branching points, and VEGF-induced angiogenesis.
- Combines with VEGFA to reduce A375P (malignant melanoma) spheroid outgrowth.
- Blocks TGFβ production by Nrp1+ regulatory T-cell SMAD3/AKT (Tregs).
- Exhibits a half-life of 4.29 h in mice, supporting once-daily dosing.
Medchemexpress LLC Nifenalol hydrochloride | 5704-60-9 | 99.9% | 260.72 | C11H17ClN2O3 | 25 MG
Nifenalol hydrochloride is a β-adrenergic receptor antagonist supplied as a white to off-white solid for research use. It is used in pharmacology and cardiac electrophysiology studies, including investigation of early afterdepolarization (EAD) effects. The compound is provided in milligram-scale packs and has manufacturer guidance for solid and solution storage.
- β-adrenergic receptor antagonist for pharmacological research.
- Useful for studying cardiac electrophysiology and EAD mechanisms.
- High reported purity suitable for laboratory assays (99.9%).
- White to off-white solid, stable under recommended storage.
- Available in milligram-scale pack sizes for small-scale experiments.
Medchemexpress LLC BAY-6672 hydrochloride | 2247520-31-4 | C26H28BrCl2N3O3 | 1 ML
BAY-6672 hydrochloride is a chemical compound supplied as a solid, primarily intended for laboratory research and the manufacture of substances.
- Identified for laboratory chemical applications
- Recommended storage at 4°C under nitrogen, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, under nitrogen
- Ships at room temperature if transit is less than 2 weeks
- For research use only
Medchemexpress LLC ENMD-1068 hydrochloride | 2703451-51-6 | 98.3% | 319.87 | C15H30ClN3O2 | 10MM 1ML
ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist used in biochemical and cellular research to probe PAR2 signaling and related pathways such as TGF-β1/Smad. The compound is supplied as the hydrochloride salt with high reported purity and is offered both as a ready-to-use 10 mM solution in DMSO (1 mL) and in multiple solid pack sizes for flexibility in experimental workflows.
- Selective PAR2 antagonist suitable for signaling and fibrosis research.
- Provided as the hydrochloride salt with white to off-white appearance.
- Available as a 10 mM DMSO solution (1 mL) for immediate use in assays.
- Offered in solid quantities for custom formulation and dosing.
- High reported purity (~98.3%) and defined molecular weight for reliable dosing.
- Solubility data and storage recommendations provided for in vitro and in vivo use.
Medchemexpress LLC Arc 239 dihydrochloride | 55974-42-0 | MFCD02262215; MFCD16875414 | 99.2% | 480.43 | C24H31Cl2N3O3 | 5 MG
ARC 239 dihydrochloride is a small-molecule research compound that acts as a selective α2B/α2C adrenoceptor antagonist. It is supplied as a white to off-white solid intended for in vitro pharmacology and receptor-binding studies; reported binding data indicate greater affinity at α2B compared with α2A and α2C subtypes.
- Selective antagonist of α2B and α2C adrenoceptors.
- Reported pKd/pKi values indicate higher affinity for α2B subtype.
- High purity suitable for research applications.
- White to off-white solid form for convenient handling.
- Stable under recommended refrigerated storage.
- Useful for subtype-selective adrenergic receptor studies.
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | 99.7% | 269.77 | C14H20ClNO2 | 10 MG
Piperoxan hydrochloride is a research chemical described as an α2 adrenoceptor antagonist and an early-generation antihistamine. Supplied as a solid for laboratory use, it is used as a reference compound in receptor pharmacology and biochemical studies.
- α2 adrenoceptor antagonist activity
- First-generation antihistamine properties
- High reported purity (about 99.7%) suitable for research
- Solid form supplied in small laboratory pack sizes
- Molecular formula C14H20ClNO2; molecular weight 269.77
Apexbio Technology LLC RS 127445 HCl 199864-87-4 10mM (in 1mL DMSO)
RS 127445 HCl (CAS 199864-87-4) is a small-molecule antagonist targeting the serotonin 5-HT2B receptor a member of the G-protein coupled receptor family It is designed to selectively block 5-HT2B receptor activity thereby modulating intracellular signaling pathways such as calcium elevation and inositol phosphate production RS 127445 HCl exerts its biological activity primarily through selective antagonism of the 5-HT2B receptor In isolated tissue preparations such as rat stomach fundus and jugular vein RS 127445 HCl inhibits serotonin-induced contraction Based on these pharmacological properties RS 127445 HCl holds research potential in studies of 5-HT2B receptor function and related physiological processes
Medchemexpress LLC SB-258585 hydrochloride | 1216468-02-8 | 99.7% | 523.82 g/mol | C18H23ClIN3O3S | 10 MG
SB-258585 hydrochloride is a research compound used as a high-affinity ligand and antagonist for the serotonin 5-HT6 receptor (CAS 1216468-02-8). Supplied as the hydrochloride salt, it has molecular formula C18H23ClIN3O3S, molecular weight 523.82 g/mol, and is provided for in vitro and ex vivo pharmacological and receptor-binding studies.
- High-affinity antagonist of the serotonin 5-HT6 receptor.
- High reported purity, suitable for analytical and biological assays.
- Appropriate for radioligand binding and receptor labeling studies.
- Supplied in small-mass research quantities for laboratory use.
- Molecular weight 523.82 g/mol and defined molecular formula.
Medchemexpress LLC TG 100572 hydrochloride | 867331-64-4 | MFCD18251422 | 98.8% | 512.43 g/mol | C26H27Cl2N5O2 | 50 MG
TG 100572 Hydrochloride is a multi-targeted kinase inhibitor supplied as a hydrochloride salt for laboratory research. It inhibits several receptor tyrosine kinases and Src family kinases and is used in vitro to study signaling pathways and kinase-dependent cellular processes. Offered in multiple pack sizes with high listed purity for biochemical and cell-based studies.
- Multi-targeted kinase inhibition profile (VEGFR, FGFR, PDGFR, Src family).
- High listed purity suitable for in vitro assays.
- Available in small pack sizes and solution format for flexibility.
- Compatible with biochemical and cell-based assay workflows.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Nisoxetine | 53179-07-0 | 98.6% | 100 MG
Nisoxetine is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. It functions as an antidepressant and local anesthetic, capable of blocking voltage-gated sodium channels. This product is intended for research use only.
- Potently and selectively inhibits the noradrenaline transporter (NET) with a Kd of 0.76 nM.
- Acts as both an antidepressant and a local anesthetic.
- Can block voltage-gated sodium channels.
- Available in multiple quantities.
- Comes with a data sheet, COA, SDS, and handling instructions.
- Detailed solubility information provided for in vitro use.
Medchemexpress LLC Angoline hydrochloride | 21080-31-9 | 5 MG
Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
- Potent and selective IL6/STAT3 signaling pathway inhibitor
- IC50 of 11.56 μM
- Inhibits STAT3 phosphorylation
- Inhibits its target gene expression
- Inhibits cancer cell proliferation
- Purity: >98%