Hydrochlorides
Medchemexpress LLC Rx 801077 hydrochloride | 89196-95-2 | 99.8% | 222.67 g/mol | C11H11ClN2O | 50 MG
RX 801077 hydrochloride (2 BFI) is a selective imidazoline I2 receptor agonist used in neuroscience research. It exhibits nanomolar binding affinity to I2 receptors and has been reported to show anti-inflammatory and neuroprotective effects relevant to traumatic brain injury and receptor pharmacology studies.
- Selective imidazoline I2 receptor agonist.
- High purity: 99.8%.
- Hydrochloride salt for improved stability and handling.
- Suitable for in vitro and in vivo pharmacology research.
- Molecular weight: 222.67 g/mol.
- Reported anti-inflammatory and neuroprotective activity.
- Available as a 50 MG research-size package.
![Medchemexpress LLC Benzenemethanamine, N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-, hydrochloride (1:1), (αS)- | 129938-20-1 | 99.96% | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzenemethanamine, N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-, hydrochloride (1:1), (αS)- | 129938-20-1 | 99.96% | 5 MG
Benzenemethanamine, N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-, hydrochloride (1:1), (αS)- | 129938-20-1 | 99.96% | 5 MG
Medchemexpress LLC Nisoxetine hydrochloride | 57754-86-6 | MFCD00078426 | 99.92% | 5 MG
Nisoxetine hydrochloride is a potent and selective inhibitor of the noradrenaline transporter (NET), with a Kd of 0.76 nM. It functions as an antidepressant and local anesthetic by blocking voltage-gated sodium channels.
- Potent and selective inhibitor of noradrenaline transporter (NET)
- Acts as an antidepressant
- Functions as a local anesthetic
- Blocks voltage-gated sodium channels
eMolecules 21987-29-1 | 4,4-DIFLUOROPIPERIDINE | AstaTech | MFCD03094281 | 121.131 | C5H9F2N | 95.000 | FC1(F)CCNCC1 | 5g | 261434923
4,4-DIFLUOROPIPERIDINE | AstaTech | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 95.000 | FC1(F)CCNCC1 | 5g | 261434923
eMolecules 21987-29-1 | 4,4-DIFLUOROPIPERIDINE | AstaTech | MFCD03094281 | 121.131 | C5H9F2N | 95.000 | FC1(F)CCNCC1 | 1g | 261434922
4,4-DIFLUOROPIPERIDINE | AstaTech | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 95.000 | FC1(F)CCNCC1 | 1g | 261434922
Apexbio Technology LLC VU 0361737 1161205-04-4 5mg
VU 0361737 (CAS 1161205-04-4) is a selective brain-penetrant positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4) It demonstrates high selectivity for mGluR4 over other mGluR subtypes with EC50 values of 240 nM for human and 110 nM for rat mGluR4 and shows minimal to no activity at mGluR1 mGluR2 mGluR3 mGluR6 and mGluR7 while exhibiting weak activity at mGluR5 and mGluR8 VU 0361737 crosses the blood-brain barrier and achieves significant brain exposure (brain plasma ratio of 4 1) with a short half-life (T1/2 20 min) following administration in rats This compound is utilized in studies exploring the modulation of basal ganglia neurotransmission and the pathophysiology of Parkinson s disease
Medchemexpress LLC PIM-447 (dihydrochloride) | 1820565-69-2 | 99.8% | 513.38 | 100 MG
PIM-447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor. It displays dual antimyeloma and bone-protective effects, and induces apoptosis.
- Potent, orally available, and selective pan-PIM kinase inhibitor.
- Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively.
- Displays dual antimyeloma and bone-protective effects.
- Induces apoptosis.
Medchemexpress LLC 2-iminothiolane hydrochloride | 4781-83-3 | MFCD00039013 | 99.9% | 137.63 g/mol | C4H8ClNS | 5 MG
2-Iminothiolane hydrochloride (Traut's reagent) is a thiolating reagent that converts primary amines into sulfhydryl (-SH) groups via amidine formation, enabling modification of proteins, peptides, and glycans for downstream conjugation and crosslinking. It is provided as a high-purity solid with characterized solubility and storage recommendations for biochemical applications.
- Introduces free sulfhydryl groups into primary amines.
- Enables protein, peptide, and glycan conjugation and crosslinking.
- High purity suitable for biochemical assays.
- Soluble in water and DMSO under specified conditions.
- Stable when stored sealed at recommended temperatures.
Medchemexpress LLC CGP 54626 hydrochloride | 149184-21-4 | 99.8% | 444.76 g/mol | C18H29Cl3NO3P | 1 MG
CGP 54626 hydrochloride is a selective GABAB receptor antagonist for research use. It is supplied as a white to off-white solid with high purity and defined molecular properties, and is commonly used in receptor-binding and functional assays to study GABAB-mediated signaling.
- Selective GABAB receptor antagonist (IC50 ≈ 4 nM).
- High purity (≈99.8%).
- White to off-white solid appearance.
- Recommended storage: protected from light at -20°C; in solution -80°C for long term.
- Suitable for in vitro binding and functional assays.
- For research use only; not for human or veterinary use.
Medchemexpress LLC N-desmethyl venlafaxine hydrochloride | 93413-90-2 | MFCD18711349 | 99.9% | C16H26ClNO2 | 10MG
Wy-45494 hydrochloride (N-desmethyl venlafaxine hydrochloride) is an analytical reference standard of the major active metabolite of venlafaxine supplied as the hydrochloride salt. It is provided with documented characterization and high purity for use in analytical method development, assay validation, and pharmacological research.
- High purity suitable for analytical applications.
- Characterized molecular formula and molecular weight for identification.
- Suitable as a reference standard for chromatography and mass spectrometry.
- Demonstrated activity inhibiting norepinephrine and serotonin reuptake in vitro.
- Provided with a certificate of analysis for traceability.
- Intended for research use only.
Medchemexpress LLC L-NIO dihydrochloride | 159190-44-0 | MFCD09878280 | 97.0% | 246.13 g/mol | C7H17Cl2N3O2 | 1 ML
L-NIO dihydrochloride is a research-grade nitric oxide synthase (NOS) inhibitor provided as a ready-to-use stock solution and as solid quantities for biochemical and in vivo studies. It is used to inhibit iNOS, eNOS, and nNOS in cellular assays and animal models where controlled NOS modulation is required.
- Ready-to-use 10 mM solution in DMSO (1 mL) for consistent dosing.
- High purity suitable for research applications (97.0%).
- Well-characterized compound with CAS registration and molecular weight data.
- Available in both solution and solid formats to suit experimental needs.
- Accompanied by safety and quality documents (SDS and COA) for compliance.
- Suitable for in vitro NOS inhibition assays and in vivo ischemia models.
eMolecules 21987-29-1 | 4,4-Difluoropiperidine | Combi-Blocks | MFCD03094281 | 121.131 | C5H9F2N | 98.000 | FC1(F)CCNCC1 | 1g | 205391142
4,4-Difluoropiperidine | Combi-Blocks | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 98.000 | FC1(F)CCNCC1 | 1g | 205391142
Medchemexpress LLC JDTic dihydrochloride | 785835-79-2 | MFCD22419279 | 98.0% | 538.55 g·mol⁻¹ | C28H41Cl2N3O3 | 1 ML
JDTic dihydrochloride is the dihydrochloride salt of JDTic, a selective kappa-opioid receptor (KOR) antagonist used in research to block κ-agonist-induced antinociception. Supplied as a concentrated solution for in vitro pharmacology and receptor signaling studies.
- Selective kappa-opioid receptor antagonist suitable for pharmacology research.
- Provided as a 10 mM solution in a 1 mL vial.
- High purity appropriate for research applications.
- Soluble in DMSO and water for assay preparation.
- Commonly used for receptor antagonism and KOR signaling studies.
Medchemexpress LLC Cefotiam (hydrochloride) | 66309-69-1 | 98.0% | 25 MG
Cefotiam hydrochloride is a parenteral cephalosporin antibiotic that exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It is highly active against various bacterial strains.
- Parenteral cephalosporin antibiotic
- Broad-spectrum activity against Gram-positive and Gram-negative bacteria
- Exhibits antibacterial activity against P. mirabilis IFO 3849
- Highly active against Staph. aureus and Staph. albus
- Active against haemolytic streptococci, pneumococci, and Streptococcus viridans
- Can cure urinary tract infection with P. mirabilis in mice
Medchemexpress LLC Itopride hydrochloride | 122892-31-3 | 99.8% | 500 MG
Itopride (HSR803) hydrochloride is identified as a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. It functions as a gastrointestinal prokinetic agent by enhancing gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions. This compound is also suitable for research related to gastro-esophageal reflux disease (GERD).
- Potent dopamine-2 antagonist.
- Acetylcholine esterase (AChE) inhibitor.
- Enhances gastric motility through antidopaminergic and anti-acetylcholinesterasic actions.
- Can be utilized as a gastrointestinal prokinetic agent.
- Suitable for researching gastro-esophageal reflux disease (GERD).
- Prokinetic effects on both the ileum and colon (in vitro studies).
- Significantly accelerates gastric emptying (in vivo studies).