DPTN dihydrochloride is a potent and selective antagonist for human, mouse, and rat A3 adenosine receptors. It exhibits Ki values of 1.65 nM for human A3AR, 9.61 nM for mouse A3AR, and 8.53 nM for rat A3AR. While it is weaker at mouse and rat A3AR compared with human A3AR, it also shows reduced selectivity (approximately 20-fold) versus the A2B adenosine receptor.
- Potent and selective A3 adenosine receptor antagonist
- Effective in human, mouse, and rat models
- Solid, light yellow to yellow appearance
- Stable under recommended storage conditions