Organic lead salts
Apexbio Technology LLC Vardenafil HCl Trihydrate 330808-88-3 10mg
Vardenafil HCl Trihydrate (CAS 330808-88-3) is the trihydrate salt form of vardenafil a potent and selective inhibitor of phosphodiesterase type 5 (PDE5) In enzymatic assays vardenafil demonstrates an IC50 of 0 7 nM for PDE5 exhibiting high selectivity over other phosphodiesterase isoforms with significantly higher IC50 values for PDE1 PDE2 PDE3 PDE4 and PDE6 Vardenafil enhances relaxation of human trabecular smooth muscle in response to sodium nitroprusside acetylcholine and electrical stimulation and increases cGMP concentrations in human corpus cavernosum tissue These properties establish its utility in studies addressing cGMP-mediated smooth muscle relaxation and PDE5-related pharmacology
Medchemexpress LLC RNase L-IN-1 trihydrochloride | 98.1% | 542.67 g/mol | C27H35FN6O3S | 10 MG
RNase L-IN-1 trihydrochloride is the trihydrochloride salt form of a small-molecule inhibitor of RNase L, supplied for research use to study RNase L-mediated RNA degradation, antiviral responses, and inflammation. The compound is provided as a solid salt suitable for biochemical and cellular assays.
- Inhibits RNase L activity for mechanistic and antiviral research.
- Trihydrochloride salt form improves solubility and handling.
- High purity (~98.1%) suitable for research applications.
- Yellow to brown solid appearance, powder form for storage.
- Molecular formula C27H35FN6O3S; molecular weight 542.67 g/mol.
- Store powder at -20°C for long-term stability; follow supplier guidelines.
Medchemexpress LLC Meta-Hoechst trihydrochloride | 2320308-12-9 | 99.2% | 533.88 g·mol⁻¹ | C25H27Cl3N6O | 10 MG
HOE-S 785026 trihydrochloride is a blue fluorescent DNA nuclear stain supplied as a solid. It binds to the minor groove of double-stranded DNA and is used for nuclear staining in fluorescence microscopy and cell-based assays. Available in multiple pack sizes and high purity for research applications.
- Blue fluorescent dye suitable for DNA/nuclear staining.
- Binds the minor groove of double-stranded DNA for reliable nuclear labeling.
- High purity for reproducible experimental results.
- Available in small quantities to support assay development and optimization.
- Compatible with fluorescence microscopy and cell-based assays.
Medchemexpress LLC VO-OHpic trihydrate | 476310-60-8 | 98.0% | C12H16N2O11V | 10MG
VO-Ohpic trihydrate is a vanadium-containing small-molecule inhibitor of PTEN used in biochemical and cell-based research to probe PI3K/AKT signaling. It reversibly inhibits PTEN with low-nanomolar potency and is supplied as the trihydrate form to aid stability and handling.
- Potent PTEN inhibition (IC50 ≈ 46 ± 10 nM).
- Vanadium-containing complex for targeted phosphatase interaction.
- Suitable for biochemical and cell-based assays probing PI3K/AKT signaling.
- Trihydrate form to improve compound stability during storage and handling.
- Available in small, research-grade quantities for laboratory use.
Apexbio Technology LLC VO-Ohpic trihydrate 476310-60-8 25mg
VO-Ohpic trihydrate (CAS 476310-60-8) is a highly selective small-molecule inhibitor of the lipid phosphatase PTEN (phosphatase and tensin homolog) with an in vitro IC50 of 35 nM VO-Ohpic shows marked selectivity for PTEN over other phosphatases including CBPs SopB myotubularin SAC1 and PTP- In cell-based assays VO-Ohpic induces dose-dependent phosphorylation of Akt at Ser473 and Thr308 saturating at 75 nM and promotes Akt functional activation as indicated by decreased FoxO3a transcriptional activity In vivo VO-Ohpic administration in MDA PCa-2b tumor xenograft mice results in reduced tumor growth and increased survival This compound serves as a valuable tool for investigating PTEN function and its modulation in insulin signaling glucose uptake and cancer research
Selleck Chemical LLC Peramivir Trihydrate S2716-5mg
Peramivir Trihydrate (BCX-1812 RWJ-270201 S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent specific influenza viral neuraminidase inhibitor with an IC50 of median 0 09 nM
Selleck Chemical LLC Magnesium lactate trihydrate S4829-25mg
Magnesium lactate the magnesium salt of lactic acid is a mineral supplement that is added to some food and beverages as an acidity regulator
Selleck Chemical LLC Alendronate sodium trihydrate S1624-25mg
Alendronate sodium trihydrate (G-704650 MK-217) a nitrogen-containing bisphosphonate is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis
Apexbio Technology LLC VO-Ohpic trihydrate 476310-60-8 10mg
VO-Ohpic trihydrate (CAS 476310-60-8) is a highly selective small-molecule inhibitor of the lipid phosphatase PTEN (phosphatase and tensin homolog) with an in vitro IC50 of 35 nM VO-Ohpic shows marked selectivity for PTEN over other phosphatases including CBPs SopB myotubularin SAC1 and PTP- In cell-based assays VO-Ohpic induces dose-dependent phosphorylation of Akt at Ser473 and Thr308 saturating at 75 nM and promotes Akt functional activation as indicated by decreased FoxO3a transcriptional activity In vivo VO-Ohpic administration in MDA PCa-2b tumor xenograft mice results in reduced tumor growth and increased survival This compound serves as a valuable tool for investigating PTEN function and its modulation in insulin signaling glucose uptake and cancer research
Selleck Chemical LLC Scopolamine HBr trihydrate
Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55 3 nM