Organic lead salts
Medchemexpress LLC VO-OHpic trihydrate | 476310-60-8 | 98.0% | C12H16N2O11V | 10MG
VO-Ohpic trihydrate is a vanadium-containing small-molecule inhibitor of PTEN used in biochemical and cell-based research to probe PI3K/AKT signaling. It reversibly inhibits PTEN with low-nanomolar potency and is supplied as the trihydrate form to aid stability and handling.
- Potent PTEN inhibition (IC50 ≈ 46 ± 10 nM).
- Vanadium-containing complex for targeted phosphatase interaction.
- Suitable for biochemical and cell-based assays probing PI3K/AKT signaling.
- Trihydrate form to improve compound stability during storage and handling.
- Available in small, research-grade quantities for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences Meropenem trihydrate 98 HP50MG
Meropenem trihydrate (MRP) belongs to the carbapenem group of compounds. It is susceptible to degradation at high temperature and humidity. It is soluble in methanol-water or acetone-water combinations. It is used as an antibacterial agent for treating meningitis and pneumonia.
Sigma Aldrich Fine Chemicals Biosciences SODIUM ACETATE TRIHYDRATE 25KG
NC3368826 SODIUM ACETATE TRIHYDRATE 25KG
Medchemexpress LLC Tanuxiciclib trihydrochloride | 1983984-11-7 | ≥98.0% | 588.94 g/mol | C26H28Cl3N5O3 | 5 MG
Tanuxiciclib trihydrochloride is the trihydrochloride salt of tanuxiciclib, a cyclin-dependent kinase (CDK) inhibitor supplied as a research-grade solid for biochemical and cell-based studies of CDK signaling and cell-cycle regulation. The compound is provided with high chemical purity and is intended for laboratory research applications only.
Selleck Chemical LLC Magnesium lactate trihydrate S4829-25mg
Magnesium lactate the magnesium salt of lactic acid is a mineral supplement that is added to some food and beverages as an acidity regulator
Medchemexpress LLC VO-Ohpic trihydrate | 476310-60-8 | 98.0% | 200 MG
VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC50 of 46±10 nM. It is a sterically demanding molecule that significantly inhibits PTEN activity in low nanomolar concentrations. It is considered an encouragingly specific and potent PTEN inhibitor and is the most potent inhibitor (IC50=35 nM) of the PTEN lipid phosphatase activity.
- Potent PTEN inhibitor
- IC50 of 46±10 nM
- Significantly inhibits PTEN activity in low nanomolar concentrations
- Considered specific and potent
- Most potent inhibitor of PTEN lipid phosphatase activity
- Used in research
Medchemexpress LLC VO-Ohpic (trihydrate) | 476310-60-8 | 98.0% | 1 ML
VO-Ohpic (trihydrate) is a highly potent inhibitor of PTEN, with an IC50 of 46±10 nM. It has a molecular weight of 415.20 and a chemical formula of C12H16N2O11V. This compound appears as a solid, ranging in color from light green to green.
- Significantly inhibits PTEN activity at low nanomolar concentrations (IC50, 46±10 nM).
- Demonstrates inhibition constants Kic and Kiu of 27±6 nM and 45±11 nM, respectively.
- Acts as a specific and potent PTEN inhibitor.
- Inhibits PTEN in mice via intra-peritoneal injection (10 μg/kg) 30 minutes before ischemia.
- Significantly decreases myocardial infarct size in treated mice.
Apexbio Technology LLC Peramivir Trihydrate 1041434-82-5 10mg
Peramivir Trihydrate (CAS 1041434-82-5) is a small-molecule inhibitor targeting influenza viral neuraminidase It is designed to inhibit neuraminidase activity thereby impeding viral particle release and the spread of infection Peramivir Trihydrate exerts its biological activity primarily through competitive inhibition of neuraminidase as a transition-state analog In experimental studies Peramivir Trihydrate demonstrates neuraminidase inhibitory activity with an IC50 of approximately 0 09 nM Based on these pharmacological properties Peramivir Trihydrate holds research potential in investigating influenza virus replication antiviral efficacy and neuraminidase-mediated viral dissemination
Apexbio Technology LLC Vardenafil HCl Trihydrate 330808-88-3 10mg
Vardenafil HCl Trihydrate (CAS 330808-88-3) is the trihydrate salt form of vardenafil a potent and selective inhibitor of phosphodiesterase type 5 (PDE5) In enzymatic assays vardenafil demonstrates an IC50 of 0 7 nM for PDE5 exhibiting high selectivity over other phosphodiesterase isoforms with significantly higher IC50 values for PDE1 PDE2 PDE3 PDE4 and PDE6 Vardenafil enhances relaxation of human trabecular smooth muscle in response to sodium nitroprusside acetylcholine and electrical stimulation and increases cGMP concentrations in human corpus cavernosum tissue These properties establish its utility in studies addressing cGMP-mediated smooth muscle relaxation and PDE5-related pharmacology
Apexbio Technology LLC Peramivir Trihydrate 1041434-82-5 50mg
Peramivir Trihydrate (CAS 1041434-82-5) is a small-molecule inhibitor targeting influenza viral neuraminidase It is designed to inhibit neuraminidase activity thereby impeding viral particle release and the spread of infection Peramivir Trihydrate exerts its biological activity primarily through competitive inhibition of neuraminidase as a transition-state analog In experimental studies Peramivir Trihydrate demonstrates neuraminidase inhibitory activity with an IC50 of approximately 0 09 nM Based on these pharmacological properties Peramivir Trihydrate holds research potential in investigating influenza virus replication antiviral efficacy and neuraminidase-mediated viral dissemination
Selleck Chemical LLC Peramivir Trihydrate S2716-5mg
Peramivir Trihydrate (BCX-1812 RWJ-270201 S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent specific influenza viral neuraminidase inhibitor with an IC50 of median 0 09 nM
Selleck Chemical LLC Irinotecan HCl Trihydrate S2217-100mg
Irinotecan HCl Trihydrate is a hydrochloride trihydrate of irinotecan (Camptosar Campto CPT-11) which is a topoisomerase I inhibitor with IC50 of 15 8 and 5 17 M for LoVo cells and HT-29 cells respectively