Vinyl halides
![Medchemexpress LLC Benzo[c]-2,6-naphthyridine-8-carboxylic acid, 5-[(3-chlorophenyl)amino]-, sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzo[c]-2,6-naphthyridine-8-carboxylic acid, 5-[(3-chlorophenyl)amino]-, sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 1 ML
Silmitasertib sodium salt is an orally bioavailable, highly selective, and potent CK2 inhibitor with IC50 values of 1 nM against CK2α and CK2α'. It exhibits potent anti-cancer activity.
- Orally bioavailable and potent CK2 inhibitor
- Highly selective for CK2α and CK2α'
- Causes cell-cycle arrest and induces apoptosis in cancer cells
- Attenuates PI3K/Akt signaling
- Demonstrates robust antitumor activity in murine xenograft models
- Suitable for research use only
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.92% | C19H11ClN3NaO2 | 1 G
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'. It induces cell-cycle arrest and selectively induces apoptosis in cancer cells, attenuates PI3K/Akt signaling, and its antiproliferative activity correlates with CK2α catalytic subunit expression. It also prevents leukemic cells from engaging a functional UPR and decreases pro-survival ER chaperon BIP/Grp78 expression.
- Highly selective and potent CK2 inhibitor (IC50 of 1 nM against CK2α and CK2α')
- Induces cell-cycle arrest and selective apoptosis in cancer cells
- Attenuates PI3K/Akt signaling and suppresses CK2-mediated PI3K/Akt/mTOR signaling
- Exerts anti-proliferative effects in hematological tumors
- Prevents leukemic cells from engaging a functional UPR and decreases pro-survival ER chaperon BIP/Grp78 expression
Medchemexpress LLC Alizarin Red S sodium | 130-22-3 | 25 MG
Alizarin Red S sodium is an anthraquinone-derived dye that binds calcium ions and is used to stain mineralized deposits in biological samples. It is commonly used in histology and cell biology to assess osteoblast differentiation and bone formation.
- Stains calcium deposits for histology and cell-based assays.
- Forms complexes with calcium for visualization of mineralized matrix.
- Water-soluble sodium salt suitable for aqueous staining procedures.
- Supplied in small laboratory quantities for research use.
Medchemexpress LLC Silmitasertib sodium salt | 1309357-15-0 | 99.9% | C19H11ClN3NaO2 | 100 MG
Silmitasertib sodium salt is an orally bioavailable, highly selective and potent CK2 inhibitor.
- Causes cell-cycle arrest and selectively induces apoptosis in cancer cells by attenuating PI3K/Akt signaling.
- Antiproliferative activity correlates with CK2α catalytic subunit expression.
- Prevents leukemic cells from engaging UPR during PS-341 treatment, reducing BIP/Grp78 expression.
- Induces cytotoxicity and apoptosis, exerting anti-proliferative effects in hematological tumors.
- Demonstrates robust antitumor activity and reduces phospho-p21 (T145) in murine xenograft models.
Medchemexpress LLC Inclisiran sodium, sense strand | 00-00-0 | 97.4% | 10MG
SS-Inclisiran (sodium) is the sense strand component of inclisiran, a chemically synthesized small interfering RNA (siRNA) designed to reduce PCSK9 expression by targeting PCSK9 mRNA. Supplied as the sodium salt for laboratory research, it is intended for use in molecular biology studies of lipid regulation and gene silencing.
- Sense strand of an siRNA targeting PCSK9.
- Sodium salt form suitable for research applications.
- Reported purity approximately 97.4%.
- Available in multiple mass sizes for experimental flexibility.
- Intended for research use only, not for therapeutic use.
eMolecules 76334-36-6 | 3-Bromo-3-buten-1-ol | Combi-Blocks, Inc. | MFCD00154041 | 151.003 | C4H7BrO | 97.000 | OCCC(Br)=C | 5g | 589788044
3-Bromo-3-buten-1-ol | Combi-Blocks, Inc. | 76334-36-6 | MFCD00154041 | 151.003 | C4H7BrO | 97.000 | OCCC(Br)=C | 5g | 589788044
Medchemexpress LLC Rp-8-Br-cAMPS sodium | 925456-59-3 | 446.15 | 1 MG
Rp-8-Br-cAMPS sodium is an analog of cAMP and an inhibitor of PKA. It occupies cAMP binding sites on PKA type I regulatory subunits, preventing PKA dissociation and activation. It can be used in the study of tumors and retrovirus-induced immune deficiency. Rp-8-Br-cAMPS sodium also inhibits insulin secretion.
- Completely blocks the ability of 2-chloroadenosine to inhibit LAK cytotoxicity.
- Significantly reduces the inhibitory effect of 2-chloroadenosine on cytokine production.
- Inhibits insulin secretion in 832/13 cells.
- Improves immune function in a mouse retrovirus infection model.
Medchemexpress LLC Ethylene-vinyl acetate copolymer | 24937-78-8 | MFCD00133996 | 40.0% | (C4H6O2.C2H4)x | 25 G
Ethylene-vinyl acetate copolymer (CAS 24937-78-8) is a research-grade copolymer used as a biochemical reagent or biological material in life-science research. The material is reported as a white to off-white liquid with a density of 0.948 g/cm³ and typical vinyl acetate content near 40 wt%. It is intended for laboratory and research applications where a vinyl-containing ethylene copolymer is required.
- Research-grade copolymer for laboratory applications.
- Suitable as a biological material or organic reagent in life-science studies.
- White to off-white liquid form with reported density 0.948 g/cm³.
- Typical vinyl acetate content approximately 40.0% (wt%).
- Available in small lab-scale packages for controlled use.
eMolecules 5162-44-7 | 4-Bromo-1-butene, stab. with silver | Oakwood Chemical | MFCD00000258 | 135.004 | C4H7Br | 97.000 | BrCCC=C | 500g | 746319780
4-Bromo-1-butene, stab. with silver | Oakwood Chemical | 5162-44-7 | MFCD00000258 | 135.004 | C4H7Br | 97.000 | BrCCC=C | 500g | 746319780