Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC I-PEG5-OH 1g
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 hydrochloride | 2097971-11-2 | MFCD31656714 | >95.0% | 656.23 | C30H46ClN5O7S | 2 G
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a VHL E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for use in PROTAC development and related chemical biology research. It is a PEG3-linked derivative of the AHPC VHL ligand and is provided in multiple packaged sizes for synthesis and assay workflows.
- VHL E3 ligase ligand-linker conjugate suitable for PROTAC design.
- Provided as the hydrochloride salt for improved solubility and handling.
- Available in multiple sizes, including 2 G.
- Molecular formula C30H46ClN5O7S; molecular weight 656.23.
- Purity ≥95% by supplier specification.
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Medchemexpress LLC Azido-PEG3-C6-Cl | 1625717-44-3 | 95.3% | 293.79 | 50 MG
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Azido-PEG3-C6-Cl | 1625717-44-3 | 95.3% | 293.79 | 50 MG
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Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 hydrochloride | 2097971-11-2 | MFCD31656714 | 99.0% | 656.23 g/mol | C30H46ClN5O7S | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a VHL E3 ligase ligand-linker conjugate featuring an AHPC-derived VHL-binding warhead connected to a three-unit polyethylene glycol spacer terminating in a primary amine; it is supplied as the hydrochloride salt and is used as a building block in PROTAC synthesis and E3 ligase ligand studies.
- Contains AHPC-derived VHL-binding warhead with defined stereochemistry.
- Three-unit PEG spacer terminating in a primary amine for conjugation.
- Provided as the hydrochloride salt for improved stability and handling.
- Intended for use in PROTAC design and E3 ligase ligand research.
- Requires cold, inert storage and protection from light.
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Medchemexpress LLC Aminooxy-PEG3-C2-NH-Boc | 2062663-65-2 | C13H28N2O6 | 250 MG
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Aminooxy-PEG3-C2-NH-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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eMolecules 2247367-07-1 | 4,4,5,5-tetraethyl-2-(4,4,5,5-tetraethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Pharmablock366.160 | C20H40B2O4 | 97.000 | CCC1(CC)OB(OC1(CC)CC)B1OC(CC)(CC)C(CC)(CC)O1 | 250g | 867026732
4,4,5,5-tetraethyl-2-(4,4,5,5-tetraethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane | Pharmablock | 2247367-07-1366.160 | C20H40B2O4 | 97.000 | CCC1(CC)OB(OC1(CC)CC)B1OC(CC)(CC)C(CC)(CC)O1 | 250g | 867026732
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eMolecules 867062-95-1 | Fmoc-N-amido-PEG3-acid | Broadpharm | MFCD06656471 | 443.496 | C24H29NO7 | 98.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 208939971
Fmoc-N-amido-PEG3-acid | Broadpharm | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 98.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 208939971
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eMolecules 1076199-21-7 | N-BOC-PEG3-BROMIDE | AstaTech | MFCD09840081 | 356.257 | C13H26BrNO5 | 95.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCBr | 1g | 335880258
N-BOC-PEG3-BROMIDE | AstaTech | 1076199-21-7 | MFCD09840081 | 356.257 | C13H26BrNO5 | 95.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCBr | 1g | 335880258
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eMolecules 139115-92-7 | Boc-NH-PEG3 | Ambeed | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 100mg | 552604526
Boc-NH-PEG3 | Ambeed | 139115-92-7 | MFCD07357496 | 249.307 | C11H23NO5 | 97.000 | CC(C)(C)OC(=O)NCCOCCOCCO | 100mg | 552604526
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![Medchemexpress LLC Hexane, 1-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-6-chloro- | 1625717-44-3 | MFCD34471373 | 95.3% | 293.79 | C12H24ClN3O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222859.png-250.jpg)
Medchemexpress LLC Hexane, 1-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-6-chloro- | 1625717-44-3 | MFCD34471373 | 95.3% | 293.79 | C12H24ClN3O3 | 5 MG
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Azido-PEG3-C6-Cl is a PEG-based linker bearing an azide group used for click chemistry and PROTAC synthesis. It facilitates conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), providing a versatile building block for bioconjugation and linker design.
- Contains an azide functional group for efficient CuAAC reactions.
- Compatible with strain-promoted azide-alkyne cycloaddition for catalyst-free conjugation.
- PEG3 spacer improves solubility and provides linker flexibility.
- Terminal chlorohexyl enables further chemical modification.
- High purity and characterized molecular data support synthetic use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC T-Boc-aminooxy-peg5-azide | 2250216-95-4 | 95.0% | C17H34N4O8 | 25 MG
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T-Boc-aminooxy-peg5-azide | 2250216-95-4 | 95.0% | C17H34N4O8 | 25 MG
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Medchemexpress LLC Azido-PEG3-SSPy | 98.6% | 344.45 g/mol | C13H20N4O3S2 | 50 MG
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Azido-PEG3-SSPy is a cleavable three-unit polyethylene glycol (PEG3) linker that contains an azide functional group and a disulfide-pyridyldithiol (SSPy) moiety; it is designed for bioconjugation and ADC linker synthesis using click chemistry.
- Cleavable PEG3 linker enabling disulfide-mediated release.
- Azide functional group supports CuAAC and SPAAC bioconjugation.
- High purity (98.6%) suitable for research applications.
- Molecular weight 344.45 g/mol and formula C13H20N4O3S2.
- Available as a 50 MG vial and stored per manufacturer recommendations.
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Medchemexpress LLC Ms-PEG5-t-butyl ester | 870487-48-2 | C₁₆H₃₂O₉S | 250 MG
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Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 100 MG
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Applicable in cancer-programmed cell death research
- Connects two different ligands for PROTAC formation
- Targets E3 ubiquitin ligase and protein of interest
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 2-(2-(2-bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | 291.16 | C7H15BrO5S | 5 MG
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Br-PEG3-MS is a brominated, PEG-based PROTAC linker (methanesulfonate) designed for use in chemical synthesis of PROTACs and other bifunctional molecules. It provides a short PEG3 spacer with a reactive leaving group for conjugation chemistry, enabling efficient formation of linkages between ligands under standard organic conditions. For research use only.
- PEG3 spacer with a terminal bromide and methanesulfonate leaving group.
- Suitable for linker synthesis and nucleophilic substitution reactions.
- High purity (95.0% by NMR) for reliable synthetic performance.
- Low molecular weight facilitates handling in small-scale reactions.
- Available in multiple small pack sizes to support medicinal chemistry workflows.
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