Heptane
Medchemexpress LLC MID-1 100mg | 312608-54-1 | 293.30 g·mol-1 | C12H11N3O4S | 100 MG
MID-1 (Benzamide, 4-ethoxy-N-(5-nitro-2-thiazolyl); CAS 312608-54-1) is a small-molecule disruptor of the MG53-IRS-1 interaction that increases IRS-1 protein levels and enhances insulin signaling in vitro. It is supplied as a solid and as a 10 mM solution in DMSO for research use.
- Disrupts MG53-IRS-1 protein-protein interaction in vitro.
- Increases IRS-1 protein level and insulin signaling.
- Available as solid and as 10 mM DMSO solution.
- High purity (≈99.4%).
Sigma Aldrich Fine Chemicals Biosciences Heptane suitable for HPLC
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. Heptane is an environmentally preferable solvent and greener alternative to hexane for chromatographic purification and thus has been enhanced for Safer Solvents and Auxiliaries. Click here for more information.Tools and techniques for solvent selection green solvent selection guides.Heptane (n-Heptane) is a linear hydrocarbon. Its cetane number has been reported to be 56.
eMolecules 1416439-08-1 | 2-AMINOSPIRO[3.3]HEPTANE HCL | AstaTech | MFCD22689925 | 147.650 | C7H14ClN | 95.000 | Cl.NC1CC2(CCC2)C1 | 0.25g | 200610114
2-AMINOSPIRO[3.3]HEPTANE HCL | AstaTech | 1416439-08-1 | MFCD22689925 | 147.650 | C7H14ClN | 95.000 | Cl.NC1CC2(CCC2)C1 | 0.25g | 200610114
eMolecules AstaTech / 2-ETHYNYLTETRAHYDROFURAN / 0.1g / 503283468 / AT10094 / 95.000 / 76928-54-6 / MFCD26853295 / 96.129 / C6H8O
AstaTech / 2-ETHYNYLTETRAHYDROFURAN / 0.1g / 503283468 / AT10094 / 95.000 / 76928-54-6 / MFCD26853295 / 96.129 / C6H8O
Sigma Aldrich Fine Chemicals Biosciences Heptane suitable for HPLC
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. Heptane is an environmentally preferable solvent and greener alternative to hexane for chromatographic purification and thus has been enhanced for Safer Solvents and Auxiliaries. Click here for more information.Tools and techniques for solvent selection green solvent selection guides.Heptane (n-Heptane) is a linear hydrocarbon. Its cetane number has been reported to be 56.
Medchemexpress LLC Sappanchalcone | 94344-54-4 | 99.5% | C16H14O5 | 5 MG
Sappanchalcone is a flavonoid isolated from *Caesalpinia sappan L.*, which induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. It is intended for research use only.
- Flavonoid isolated from *Caesalpinia sappan L.*
- Induces caspase-dependent and AIF-dependent apoptosis
- Shows statistically significant effect on HCT116 cells
- Reduces MMP with significant increase in ROS levels
- Triggers phosphorylation of p53
- Inhibits LPS stimulated TNF alpha production in Balb/c mouse peritoneal macrophages
Medchemexpress LLC Zanzalintinib | 2367004-54-2 | C29H25FN4O5 | 10MG
Zanzalintinib is an orally active, ATP-competitive multi-receptor tyrosine kinase inhibitor used for preclinical research. It targets MET, VEGFR2, AXL, and MER, with reported cell-based IC50s in the low nanomolar range, and is provided as a research-grade compound (molecular formula C29H25FN4O5; MW 528.53). This compound is for laboratory research only and is not intended for human use.
- Multi-kinase activity against MET, VEGFR2, AXL, and MER.
- Potent cellular activity with low-nanomolar IC50 values.
- Suitable for kinase inhibition and cell-based assays.
- High purity for research applications (>98% reported).
- Stable under recommended storage when protected from light.
- Provided as a solid for preparation of stock solutions.
Medchemexpress LLC rel-Zotatifin | 2098191-54-7 | 97.3% | 487.56 g/mol | C28H29N3O5 | 5 MG
rel-Zotatifin is a research-grade small-molecule inhibitor of the eukaryotic initiation factor eIF4A, supplied as the racemic isomer for laboratory studies. It is characterized by a molecular formula of C28H29N3O5, molecular weight of 487.56 g/mol, and high purity suitable for biochemical and cellular assays.
- Racemic isomer with eIF4A inhibitory activity.
- High supplied purity for research applications.
- Supplied as a small, convenient 5 mg package for screening and assay development.
- Suitable for biochemical and cell-based translation studies.
- Molecular weight and formula provided for analytical confirmation.
Medchemexpress LLC 3'-Hydroxypuerarin | 117060-54-5 | 432.38 | 20 MG
3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. It acts as an antioxidant, exhibiting marked ONOO(-), NO•, and total ROS scavenging activities.
- Isolated from Pueraria lobata (Willd.) Ohwi.
- Acts as an antioxidant.
- Exhibits marked ONOO(-) scavenging activity.
- Exhibits marked NO• scavenging activity.
- Exhibits marked total ROS scavenging activities.
Medchemexpress LLC SR15006 | 2505001-54-5 | 99.90% | 385.87 | 100 MG
SR15006 is an inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells. In vitro studies demonstrated that SR15006 (1 μM or 10 μM) causes a significant reduction in the levels of tested cyclins over 72 hours in DLD-1 CRC cells. This product is for research use only.
- Inhibits Krüppel-like factor 5 (KLF5)
- Exhibits IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells
- Reduces cyclin levels in DLD-1 CRC cells
- For research use only
Medchemexpress LLC 1h-isoindole-1,3(2h)-dione, 2-[2-(3,4-dihydro-2,2,4-trimethyl-1(2h)-quinolinyl)-2-oxoethyl]- | 332382-54-4 | 99.4% | 362.42 | 10 MG
ML-SA1 is a selective TRPML agonist that inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. It induces autophagy and can be used for research as a broad-spectrum antiviral.
- Selective TRPML agonist
- Inhibits dengue virus 2 (DENV2) and zika virus (ZIKV)
- Promotes lysosomal acidification and protease activity
- Induces autophagy
- Broad-spectrum antiviral research
Medchemexpress LLC N'-Hexadecylthiophene-2-carbohydrazide | 2374313-54-7 | 99.43% | 10 MG
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. It inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. This product is for research use only.
- IC50 value of 0.83 μM for HDAC11
- Inhibits demyristoylation of serine hydroxymethyltransferase 2
- Does not inhibit other HDACs
- Increases fatty acylation level of SHMT2 in MCF7 cells
- Demonstrates synergistic cytotoxicity with Oxaliplatin in K562 cells
- White to off-white solid appearance
- Purity of 99.43%
Medchemexpress LLC Az506 | 2043321-54-4 | 99.7% | C33H40N6O | 10MG
AZ506 is a small-molecule inhibitor of the lysine methyltransferase SMYD2. It shows potent biochemical activity (SMYD2 IC50 = 17 nM) and reduces SMYD2-mediated p53 methylation in cells (cellular IC50 = 2.43 μM). The compound is supplied as solids in multiple sizes and as a 10 mM solution in DMSO for biochemical and cellular research applications.
- Potent SMYD2 inhibition with low nanomolar biochemical potency.
- Demonstrated cellular activity reducing p53 methylation.
- High purity suitable for research applications (99.7%).
- Available as solids in multiple sizes and as a ready-to-use DMSO solution.
- Provided with safety and data documentation for laboratory use.
Medchemexpress LLC MID-1 25mg | 312608-54-1 | 25 MG
MID-1 is a small-molecule research compound that disrupts the interaction between MG53 and IRS-1, preventing MG53-induced ubiquitination and degradation of IRS-1 and thereby increasing IRS-1 levels and insulin signaling in muscle cells. Supplied as an orange to red solid for laboratory research.
- Disrupts MG53-IRS-1 interaction
- Enhances IRS-1 expression and insulin signaling
- High purity for reliable assay performance
- Orange to red solid with good DMSO solubility
- Suitable for in vitro studies of insulin signaling and glucose uptake