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Filtered Search Results
Medchemexpress LLC Isocolumbin | 471-54-5 | 1 MG
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Isocolumbin is a diterpenoid isolated from Jateorhiza palmate Miers (Colombo root).
- Diterpenoid isolated from Colombo root.
- Acts as an endogenous metabolite.
- Involves the metabolic enzyme/protease pathway.
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Medchemexpress LLC C18H14Cl2F2N4O2S | 2505339-54-6 | MFCD34565708 | 99.8% | 459.30 | C18H14Cl2F2N4O2S | 5 MG
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This selective small-molecule inhibitor targets fibroblast activation protein (FAP) and is intended for research use. It exhibits potent FAP inhibition in vitro (IC50 = 2 nM), shows dose-dependent activity in animal studies, and is supplied as a high-purity solid with defined storage recommendations.
- Selective fibroblast activation protein inhibitor with IC50 of 2 nM.
- Also inhibits prolyl oligopeptidase with lower potency (IC50 ≈ 49 μM).
- High purity, ≥99.82% by HPLC.
- Molecular weight 459.30 g/mol and formula C18H14Cl2F2N4O2S.
- Appearance: white to off-white solid.
- Storage: keep sealed, away from moisture and light; in solvent -80°C (6 months), -20°C (1 month).
- Supplied as a small quantity suitable for in vitro and in vivo research.
- For research use only; not for human or diagnostic use.
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eMolecules 582-54-7 | AstaTech | (25-DICHLOROPHENOXY)ACETIC ACID | 0.25g | 761944089 | F79703 | 95 | MFCD02127529 | 221.03 | C8H6Cl2O3
AstaTech | (25-DICHLOROPHENOXY)ACETIC ACID | 0.25g | 761944089 | F79703 | 95.000 | 582-54-7 | MFCD02127529 | 221.030 | C8H6Cl2O3
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Medchemexpress LLC (R)-preclamol | 85976-54-1 | 99.6% | 219.32 g/mol | C14H21NO | 5 MG
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(R)-Preclamol is a dopamine receptor agonist used in neuroscience research to probe dopaminergic signaling. It activates both autoreceptors and postsynaptic dopamine receptors and has been reported to inhibit locomotor activity in mice and rats at low doses. Supplied as a solid and as a 10 mM solution in DMSO for experimental use.
- High chemical purity (99.56%).
- Molecular formula C14H21NO; molecular weight 219.32 g/mol.
- Available as solid and as a 10 mM solution in DMSO.
- Acts at autoreceptors and postsynaptic dopamine receptors.
- Suitable for pharmacology and behavioral studies in rodents.
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Medchemexpress LLC Cyclosomatostatin | 84211-54-1 | 99.8% | 779.97 | 1 MG
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Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. It can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer (CRC) cells.
- Potent somatostatin (SST) receptor antagonist
- Inhibits somatostatin receptor type 1 (SSTR1) signaling
- Decreases cell proliferation
- Decreases ALDH+ cell population size
- Decreases sphere-formation in colorectal cancer (CRC) cells
- Target for somatostatin receptor
- Involved in GPCR/G protein and neuronal signaling pathways
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Medchemexpress LLC 2-cyano-N-{[(3,4-dichlorophenyl)carbamothioyl]amino}acetamide | 656222-54-7 | MFCD00119122 | 99.8% | 303.17 | C10H8Cl2N4OS | 25MG
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iKIX1 is a small-molecule antifungal research compound that disrupts the interaction between the KIX domain of the mediator subunit CgGal11A and the activation domain of CgPdr1, and it resensitizes azole-resistant Candida glabrata in vitro. The compound has formula C10H8Cl2N4OS and a molecular weight of 303.17 g·mol⁻¹; it is supplied for research use only.
- Inhibits KIX-activation domain interaction (IC50 190.2 μM; Ki 18 μM).
- Resensitizes azole-resistant Candida glabrata in vitro.
- Supplied for research use only; not for clinical use.
- High purity (99.8% as reported by manufacturer).
- Stable as powder at -20°C for up to 3 years; in solvent stored at -80°C (6 months) or -20°C (1 month).
- Available as solid and as DMSO solution formulations for convenient handling.
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eMolecules 2447575-76-8 | Ambeed | (4R4R)-22-(Heptane-44-diyl)bis(4-phenyl-45-dihydrooxazole) | 100mg | 665578667 | A1505736 | 390.527 | C25H30N2O2
Ambeed | 2-(Phenylethynyl)benzaldehyde | 1g | 524998871 | A108980 | 59046-72-9 | MFCD09030317 | 206.244 | C15H10O
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E K INDUSTRIES N HEPTANE TECHNICAL / 5GAL
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NC1600616 N HEPTANE TECHNICAL / 5GAL
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Medchemexpress LLC 2-propenamide, 3-(3-chlorophenyl)-N-[2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl]-, (2E)- | 2505001-54-5 | 100.0% | 385.87 g·mol-1 | C16H20ClN3O4S | 5 MG
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SR15006 is a small-molecule inhibitor of Krüppel-like factor 5 (KLF5) supplied as a high-purity research reagent. It has reported activity in cell-based assays (IC50 = 41.6 nM in DLD-1/pGL4.18hKLF5p cells) and is provided with solubility and storage guidance for in vitro and in vivo use.
- Inhibits KLF5 with IC50 = 41.6 nM in DLD-1/pGL4.18hKLF5p cells.
- High purity suitable for research applications.
- Soluble in DMSO at 100 mg/mL; example in vivo formulations provided.
- Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
- Molecular formula C16H20ClN3O4S; molecular weight 385.87 g·mol-1.
- For research use only; not for human or clinical use.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380648 SP-96 100MG
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Medchemexpress LLC 2-[[(2,6-dichlorophenyl)methyl]thio]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole | 2253744-54-4 | 99.9% | 326.20 | C13H9Cl2N3OS | 50MG
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Dooku1 is a small-molecule reversible antagonist of Yoda1 that inhibits Yoda1-induced Ca2+ entry in cellular assays. It is provided for research use and is characterized by molecular formula C13H9Cl2N3OS, molecular weight 326.20, and high chemical purity for reliable in vitro experiments.
- Reversible antagonist of Yoda1, suitable for mechanistic studies.
- Demonstrated cellular activity with reported IC50 approximately 1.3 μM for Yoda1-induced Ca2+ entry.
- High purity (>99.9%) for reproducible results.
- Supplied as a compact 50 mg pack for small-scale experiments.
- Applicable to in vitro studies of mechanosensitive ion channel signaling.
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Aobchem AOBCHEM
5001037672 2-OXASPIRO 3.3 HEPTANE 6-BROM
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eMolecules 159751-46-9 | (S)-2-FMOC-AMINO-HEPTANEDIOIC ACID 7-TERT-BUTYL ESTER | AstaTech | MFCD08166552 | 453.535 | C26H31NO6 | 95.000 | CC(C)(C)OC(=O)CCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 0.25g | 410721239
(S)-2-FMOC-AMINO-HEPTANEDIOIC ACID 7-TERT-BUTYL ESTER | AstaTech | 159751-46-9 | MFCD08166552 | 453.535 | C26H31NO6 | 95.000 | CC(C)(C)OC(=O)CCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 0.25g | 410721239
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eMolecules 54-92-2 | N'-ISOPROPYLISONICOTINOHYDRAZIDE | AstaTech | MFCD00153819 | 179.223 | C9H13N3O | 97.000 | CC(C)NNC(=O)c1ccncc1 | 0.25g | 256638582
N'-ISOPROPYLISONICOTINOHYDRAZIDE | AstaTech | 54-92-2 | MFCD00153819 | 179.223 | C9H13N3O | 97.000 | CC(C)NNC(=O)c1ccncc1 | 0.25g | 256638582
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Medchemexpress LLC 2-Propenamide, 3-(3-chlorophenyl)-N-[2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl]-, (2E)- | 2505001-54-5 | 99.9% | 385.87 | 50 MG
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SR15006 is an inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells. It causes a significant reduction in the levels of tested cyclins over 72 hours in DLD-1 CRC cells at concentrations of 1 μM or 10 μM. This product is for research use only.
- Inhibits Krüppel-like factor 5 (KLF5)
- IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells
- Causes a significant reduction in cyclin levels over 72 hours
- Appearance: solid, white to off-white
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