Tetrahydrofuran
Medchemexpress LLC 1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea | 2260969-36-4 | MFCD34579587 | 99.5% | C20H29N3O3S | 10MG
Selnoflast is an orally active, potent, selective, and reversible small-molecule inhibitor of the NLRP3 inflammasome for research use. It is supplied as a white to off-white solid with high reported purity, and the manufacturer provides solubility and storage guidance for preparation and stability in in vitro and preclinical workflows.
- Potent and selective NLRP3 inflammasome inhibition.
- Reversible small-molecule mechanism enabling temporal studies.
- High reported purity for consistent experimental results.
- Solid form suitable for standard laboratory storage and handling.
- Documented solubility in DMSO and alkaline media with preparation notes.
- Specified storage recommendations for powder and solution stability.
- Multiple pack sizes available to support different study scales.
Medchemexpress LLC Linzagolix | 935283-04-8 | 99.7% | 508.4 g/mol | C22H15F3N2O7S | 5 MG
Linzagolix is a non-peptide, orally active gonadotropin-releasing hormone (GnRH) receptor antagonist used in laboratory research into estrogen-dependent conditions such as uterine fibroids, endometriosis, and adenomyosis. Supplied as a small, high-purity solid for research use only (not for human or veterinary use).
- Non-peptide, orally active GnRH antagonist
- Applicable to uterine fibroids, endometriosis, and adenomyosis research
- High chemical purity suitable for analytical and pharmacological studies
- Supplied in a small 5 mg pack for assay development and pilot studies
- Molecular weight 508.4 g/mol
Medchemexpress LLC Taurohyodeoxycholic 10mg | 386523 | 10 MG
Taurohyodeoxycholic acid is a taurine-conjugated 6α-hydroxylated bile acid used in biochemical and preclinical research to investigate liver and intestinal inflammation. It modulates inflammatory markers such as MPO, TNF-α, IL-6, and COX-2, and is applied in models of nonalcoholic fatty liver disease, colitis, and biliary disorders.
- Purity: 99.7%
- Molecular weight: 499.7 g·mol⁻¹
- Chemical formula: C26H45NO6S
- Available as small solid aliquots (for example 10 MG) and as DMSO solution (10 mM x 1 mL)
- Suitable for in vitro assays and in vivo disease models
- Datasheet and SDS available for handling and safety information
![Medchemexpress LLC 2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl boronic acid | 1648843-04-2 | 99.7% | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234135.png-250.jpg)
Medchemexpress LLC 2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl boronic acid | 1648843-04-2 | 99.7% | 10 MG
SX-682 is an orally bioavailable small-molecule allosteric inhibitor of chemokine receptors CXCR1 and CXCR2 under clinical investigation for oncology indications; it blocks recruitment of myeloid-derived suppressor cells and can enhance T-cell activity.
- Orally bioavailable small-molecule CXCR1/2 inhibitor
- Blocks recruitment of myeloid-derived suppressor cells (MDSCs)
- Enhances T-cell activation and antitumor immune responses
- Demonstrated activity in preclinical tumor models and clinical trials
- Supplied with high purity (typical >99%) and available in small-mass packaging for research
Medchemexpress LLC Pelcitoclax | 1619923-36-2 | 99.7% | 1281.85 | 10 MG
Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects. It is for research use only. In vitro, APG-1252 changes to a reactive metabolite named APG-1252-M1, which has remarkable antitumor effects in acute myeloid leukemia. In vivo, Pelcitoclax (APG-1252) treatment inhibits xenograft tumor growth.
- Potent Bcl-2/Bcl-xl inhibitor
- Antineoplastic and pro-apoptotic effects
- Changes to reactive metabolite APG-1252-M1 with antitumor effects in acute myeloid leukemia
- Inhibits xenograft tumor growth in vivo
- Solid appearance
- White to off-white color
Medchemexpress LLC Broflanilide | 1207727-04-5 | 99.0% | 663.28 | 2 MG
Broflanilide is a potential insecticide that metabolizes to Desmethyl-Broflanilide. Desmethyl-Broflanilide is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, inhibiting S. litura RDL GABAR with an IC50 value of 1.3 nM.
- It is a potential insecticide.
- It metabolizes into an active form, Desmethyl-Broflanilide.
- The metabolite, Desmethyl-Broflanilide, acts as a potent antagonist at the insect GABA Receptor.
- The metabolite demonstrates selective inhibition against S. litura RDL GABAR, with an IC50 of 1.3 nM.
- The metabolite exhibits weak activity against human and mammalian GABAA receptors and human glycine receptors.
Medchemexpress LLC Bevurogant | 1817773-66-2 | 99.5% | 532.62 g·mol⁻¹ | C26H28N8O3S | 5 MG
Bevurogant is a small-molecule antagonist of the retinoid-related orphan receptor gamma t (RORγt) supplied for laboratory research into immune signaling and chronic inflammatory disease models. It is provided as a solid and as a DMSO solution for in vitro and preclinical studies.
- Small-molecule RORγt antagonist for modulation of Th17-related pathways.
- High purity: 99.54% suitable for research assays.
- Chemical formula C26H28N8O3S; molecular weight 532.62 g·mol⁻¹.
- Available as solid and 10 mM solution in DMSO for flexible use.
- Intended for in vitro and preclinical research on chronic inflammatory disease models.
Medchemexpress LLC Csf1r-in-1 | 2095849-04-8 | 98.0% | 479.45 g/mol | C25H20F3N5O2 | 10 MG
CSF1R-IN-1 is a potent small-molecule inhibitor of colony stimulating factor 1 receptor (CSF1R) with sub-nanomolar cellular potency. It is supplied for research use to probe CSF1R signaling, macrophage biology, and related disease models.
- Potent CSF1R inhibition with reported IC50 of 0.5 nM.
- High purity: 98.04%.
- Molecular formula C25H20F3N5O2 and molecular weight 479.45 g/mol.
- Available in powder and ready-to-use DMSO solutions; common pack sizes include 10 mg.
- Storage: powder at -20 °C; in solvent at -80 °C (up to 6 months) or -20 °C (up to 1 month).
- For research use only, not intended for human or veterinary use.
Medchemexpress LLC DS08210767 | 2376334-75-5 | 99.4% | 513.67 g/mol | C31H39N5O2 | 100MG
DS08210767 is a small-molecule antagonist of parathyroid hormone receptor 1 (PTHR1), described as highly potent and orally bioavailable with an IC50 of 90 nM. It is provided as a research-grade, well-characterized compound suitable for receptor pharmacology and oral in vivo studies.
- High potency (IC50 of 90 nM) for PTHR1 inhibition.
- Orally bioavailable, enabling oral dosing in pharmacology studies.
- High purity (99.4%) as verified by certificate of analysis.
- Molecular weight 513.67 g/mol; formula C31H39N5O2.
- Analytical data available: COA, HNMR, and LCMS.
- Supplied in multiple milligram pack sizes for experimental flexibility.
eMolecules 22929-52-8 | 3-Oxotetrahydrofuran | Combi-Blocks | MFCD07778393 | 86.090 | C4H6O2 | 98.000 | O=C1CCOC1 | 25g | 213791601
3-Oxotetrahydrofuran | Combi-Blocks | 22929-52-8 | MFCD07778393 | 86.090 | C4H6O2 | 98.000 | O=C1CCOC1 | 25g | 213791601
![Medchemexpress LLC D-serine, N-[[2-[(3-cyanophenyl)methoxy]-4-...]] hydrochloride (1:1) | 2113650-04-5 | 98.0% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231185.png-250.jpg)
Medchemexpress LLC D-serine, N-[[2-[(3-cyanophenyl)methoxy]-4-...]] hydrochloride (1:1) | 2113650-04-5 | 98.0% | 50 MG
BMS-1001 hydrochloride is a small-molecule inhibitor of the PD-1/PD-L1 interaction supplied as the hydrochloride salt for research use. It is described as orally active and exhibits low cellular toxicity, and is provided as a solid with high purity suitable for cellular assays and interaction studies.
- Orally active PD-1/PD-L1 interaction inhibitor.
- High purity (98.0%).
- Molecular weight 631.11 g·mol⁻1.
- Solid appearance; store sealed and away from moisture.
- Storage in solvent: -80°C up to 6 months, -20°C up to 1 month.
- Available in small milligram pack sizes for research use.
Medchemexpress LLC 4-Hydroxyantipyrine | 1672-63-5 | 99.9% | 100 MG
4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine and can function as a biodistribution promoter. It can increase the distribution of the concentration ratio of Citicoline and Antipyrine in the brain.
- Major metabolite of Antipyrine
- Can act as a biodistribution promoter
- Increases distribution of concentration ratio of Citicoline and Antipyrine in the brain
- Increases the tissue-to-plasma concentration ratio of Citicoline in the brain and liver
- Increases the tissue-to-plasma concentration ratio of thiopental sodium in the brain, liver, and heart
- Enhances the blood-brain barrier (BBB) permeability of Antipyrine
Medchemexpress LLC Isoformononetin | 486-63-5 | 10 MG
Isoformononetin is an analog of Daidzein with immunoprotective effects, inhibiting the differentiation of Th17 and B-cells lymphopoiesis to promote osteogenesis in estrogen-deficient bone loss conditions.
- Molecular formula: C₁₆H₁₂O₄
- Molecular weight: 268.26
- Storage: 4°C, protected from light; in solvent: -80°C for 6 months, -20°C for 1 month (protected from light)
- Solubility (in vitro): DMSO at 250 mg/mL (931.93 mM), requires ultrasonic
- Usage caution: Product has not been fully validated for medical applications; for research use only
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran anhydrous
Tetrahydrofuran (THf) is a saturated cyclic ether with a potential use as a biofuel. Its combustion studies have been investigated. Reports suggest that it is a better promoter than 1 3 dioxolane for CO2-hydrate formation.
