Tetrahydrofuran
eMolecules 1192-30-9 | TETRAHYDROFURFURYL BROMIDE | AstaTech | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 25g | 449775921
TETRAHYDROFURFURYL BROMIDE | AstaTech | 1192-30-9 | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 25g | 449775921
Medchemexpress LLC Alendronic acid | 66376-36-1 | 98.0% | 100 MG
Alendronic acid is an orally active bisphosphonate that binds to bone surfaces and inhibits bone resorption by osteoclasts. It induces skeletal alterations in the chicken embryonic development model and can be used for osteoporosis research.
- Inhibits bone resorption by osteoclasts.
- Induces skeletal alterations in chicken embryonic development model.
- Useful for osteoporosis research.
- Orally active bisphosphonate.
eMolecules 890092-04-3 | Ambeed | 4-(Dimethylamino)picolinic acid | 100mg | 569096432 | A543061 | MFCD04971955 | 166.18 | C8H10N2O2
Ambeed | 4-(Dimethylamino)picolinic acid | 100mg | 569096432 | A543061 | 890092-04-3 | MFCD04971955 | 166.180 | C8H10N2O2
Medchemexpress LLC Vebicorvir | 2090064-66-5 | 99.7% | 467.44 | 50 MG
Vebicorvir is a first-generation inhibitor of the hepatitis B virus (HBV) core protein. It effectively suppresses the formation of covalently closed circular DNA (cccDNA) in de novo infection models, with EC50 values ranging from 1.84 μM to 7.3 μM. This compound inhibits pgRNA, HBeAg, and HBsAg production.
- First-generation hepatitis B virus (HBV) core protein inhibitor.
- Suppresses cccDNA formation in de novo infection models.
- Inhibits pgRNA, HBeAg, and HBsAg production.
Medchemexpress LLC Bifenthrin | 82657-04-3 | 99.8% | 50 MG
Bifenthrin is a synthetic pyrethroid insecticide that prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, which disrupts neural function.
- Effective against *A. gambiae* and *C. quinquefasciatus*
- Demonstrates good lethality against susceptible and resistant mosquitoes
- Effectively inhibits blood sucking
- Suitable for development as a mosquito-removal netting material
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor-free, suitable for HPLC, >=99.9% | 109-99-9 | MFCD00005356 | 100ML
Tetrahydrofuran inhibitor-free, suitable for HPLC, >=99.9% | Purity: >=99.9% | Mol Wt: 72.11 | 109-99-9 | MFCD00005356 | 100ML
Medchemexpress LLC Broflanilide | 1207727-04-5 | 99.0% | 663.28 | 100 MG
Broflanilide is an insecticide that converts into Desmethyl-Broflanilide, a powerful antagonist at the insect RDL GABA Receptor. This mechanism inhibits *S. litura* RDL GABAR with an IC50 of 1.3 nM. Desmethyl-Broflanilide shows limited activity against human GABAA α1β2γ2 receptor, mammalian GABAA α1β3γ2 receptor, and human glycine receptor (GlyR) α1β with IC50s greater than 3 μM, and less potent inhibition of GlyR α1-A288Gβ and GlyR α1-A288G (IC50s, 0.706, 0.149 μM).
- Acts as a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor.
- Inhibits *S. litura* RDL GABAR.
- Exhibits weak activity against human and mammalian GABAA receptors.
- Less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G.
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable Feedstocks. Click here for more information.2-Methyltetrahydrofuran (2-MTHF) a 2-methyl substituted tetrahydrofuran is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis. It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether. The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide.
Medchemexpress LLC Ro5-3335 | 30195-30-3 | 99.35% | 259.69 | 100 MG
Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. It is a RUNX1-CBFβ interaction inhibitor that represses RUNX1/CBFB-dependent transactivation.
- Exhibits antiproliferative activity against human CBF leukemia cell lines.
- Inhibits definitive hematopoiesis in zebrafish embryos.
- Modifies the conformation or increases the distance between the components of the RUNX1-CBFβ complex.
- Identified as an inhibitor of RUNX1-CBFβ function in zebrafish models.
- Rescues preleukemic phenotype in transgenic zebrafish.
- Reduces leukemia burden in a mouse leukemia model.
Medchemexpress LLC BDP9066 | 2226507-04-4 | 98.18% | 348.44 | 50 MG
BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase (MRCK) inhibitor. It inhibits MRCKβ with an IC50 of 64 nM in SCC12 cells and has Ki values of 0.0136 nM for MRCKα and 0.0233 nM for MRCKβ. This compound demonstrates a therapeutic effect on skin cancer by reducing substrate phosphorylation.
- Potent and selective inhibitor of MRCKα and MRCKβ.
- Exhibits antiproliferative effects, particularly in hematologic cancer cells.
- Inhibits MLC phosphorylation and blocks motility and invasion of SCC12 squamous cell carcinoma.
- Topical application significantly decreases phosphorylated MRCKα S1003 staining and tumor volumes.
eMolecules 1192-30-9 | TETRAHYDROFURFURYL BROMIDE | AstaTech | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 100g | 449775922
TETRAHYDROFURFURYL BROMIDE | AstaTech | 1192-30-9 | MFCD00016894 | 165.030 | C5H9BrO | 95.000 | BrCC1CCCO1 | 100g | 449775922
Medchemexpress LLC CCT369260 | 2647503-57-7 | 99.7% | 100 MG
CCT369260 is a chemical probe and an orally active B-cell lymphoma 6 (BCL6) inhibitor. It demonstrates anti-tumor activity and exhibits an IC50 of 520 nM.
- Orally active B-cell lymphoma 6 (BCL6) inhibitor
- Exhibits anti-tumor activity
- IC50 of 520 nM against BCL6
- Significantly inhibits BCL6 in OCI-Ly1 DLBCL xenograft model (in vivo study)
Medchemexpress LLC CCT369260 | 2647503-57-7 | 99.7% | 50 MG
CCT369260 is a chemical probe and an orally active B-cell lymphoma 6 (BCL6) inhibitor with anti-tumor activity, exhibiting an IC50 of 520 nM for BCL6.
- Chemical probe and orally active B-cell lymphoma 6 (BCL6) inhibitor
- Exhibits anti-tumor activity
- IC50 of 520 nM for BCL6
- Significantly inhibits BCL6 in OCI-Ly1 DLBCL xenograft model
- Demonstrates moderate clearance with a mean oral bioavailability of 54%
- Induces BCL6 degradation in human OCI-LY1 cells
- Shows antiproliferative activity against OCI-LY1, OCI-LY3, and SUDHL4 cells
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
![Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)ca | 1224964-36-6 | 98.25% | 548.92 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403415-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)ca | 1224964-36-6 | 98.25% | 548.92 | 100 MG
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP). It shows IC50 values of approximately 1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. XL-784 is a highly potent, low-molecular-weight (1,122 g/mol) MMP inhibitor with limited aqueous solubility (20 μg/mL). It potently inhibits MMP-2, MMP-13, and ADAM10 [TNF-α-converting enzyme (TACE)] activity in vitro, with IC50 values in the range of 1-2 nM. XL-784 also inhibits MMP-9 (IC50 ~20 nM) and ADAM17 (IC50 ~70 nM) activity, but exhibits low potency for MMP-1 inhibition (IC50 ~2,000 nM). In vivo studies show that XL-784 is effective in inhibiting aortic dilatation in mice.
- Selective matrix metalloproteinases (MMP) inhibitor
- Potently inhibits MMP-2, MMP-13, and ADAM10 in vitro
- Inhibits MMP-9 and ADAM17 in vitro
- Effective in inhibiting aortic dilatation in vivo