Tetrahydrofuran
Medchemexpress LLC Rhamnocitrin | 569-92-6 | MFCD00006839 | 300.26 | 1 MG
Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons, and is applicable for studying endothelial-related inflammatory diseases and neuroprotection.
- Scavenges DPPH (IC50=28.38 mM).
- Up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE).
- Blocks NFATc3 nuclear translocation and downstream inflammatory factor expression.
- Induces heme oxygenase HO-1 expression and regulates the ERK/p38 MAPK pathway.
- Inhibits antioxidant and pro-inflammatory cytokines (e.g., IL-6, IL-8) and adhesion molecules (e.g., ICAM-1, VCAM-1).
eMolecules 1207727-04-5 | Medchem Express | Broflanilide | 5mg | 559839407 | HY-108689 | 663.285 | C25H14BrF11N2O2
ChemScene | 3-Chloro-2-fluoro-5-(trifluoromethyl)benzoic acid | 1g | 536808729 | CS-0108802 | 129931-45-9 | MFCD01631509 | 242.550 | C8H3ClF4O2
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Medchemexpress LLC N'-(4-(diethylamino)-2-hydroxybenzylidene)isonicotinohydrazide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 10 MG
RSVA405 (CAS 140405-36-3) is a small-molecule activator of AMP-activated protein kinase (AMPK) used in cellular and biochemical research. It promotes CaMKKβ-dependent AMPK activation, inhibits mTOR signaling, and can induce autophagy; supplied at high purity for research applications.
- Potent AMPK activator; reported EC50 = 1 μM.
- High purity (~99.7%).
- Molecular formula C17H20N4O2; molecular weight 312.37 g/mol.
- Soluble in DMSO; available as solid or DMSO solution.
- For research use only; not for human consumption.
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Synthonix - Stock | MFCD09878873 | 198.003 | C4H7IO | 95.000 | IC1CCOC1 | 5g | 525918605
3-Iodotetrahydrofuran | Synthonix - Stock | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 95.000 | IC1CCOC1 | 5g | 525918605
Strem, An Ascensus Company CAS 920-39-8. 0.25mole. i-Propylmagnesium bromide 2.9M (35wt% 1wt%) in 2-methyltetrahydrofuran. MFCD00672110
CAS 920-39-8. 0.25mole. i-Propylmagnesium bromide 2.9M (35wt% 1wt%) in 2-methyltetrahydrofuran. MFCD00672110. Molecular Weight 147.30. Molecular Formula (CH3)2CHMgBr. Color/form liq. Strem 12-0825. http//www.strem.com/catalog/v/12-0825/
Medchemexpress LLC Ceftaroline | 189345-04-8 | 98.5% | 604.70 | C22H20N8O5S4 | 5 MG
Ceftaroline is an N-phosphono-type cephalosporin, the active metabolite form used in research to evaluate antibacterial activity against gram-positive and gram-negative organisms. It is supplied as a white to yellow solid for laboratory use and is suitable for in vitro and preclinical assays.
- Antibacterial cephalosporin active metabolite.
- Suitable for in vitro and preclinical research.
- Supplied as a solid, white to yellow appearance.
- Available in small vial sizes for assay work.
- High reported purity (98.5%).
- Molecular weight 604.70.
Medchemexpress LLC Broflanilide | 1207727-04-5 | 99.0% | 663.28 | 100 MG
Broflanilide is an insecticide that converts into Desmethyl-Broflanilide, a powerful antagonist at the insect RDL GABA Receptor. This mechanism inhibits *S. litura* RDL GABAR with an IC50 of 1.3 nM. Desmethyl-Broflanilide shows limited activity against human GABAA α1β2γ2 receptor, mammalian GABAA α1β3γ2 receptor, and human glycine receptor (GlyR) α1β with IC50s greater than 3 μM, and less potent inhibition of GlyR α1-A288Gβ and GlyR α1-A288G (IC50s, 0.706, 0.149 μM).
- Acts as a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor.
- Inhibits *S. litura* RDL GABAR.
- Exhibits weak activity against human and mammalian GABAA receptors.
- Less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G.
Medchemexpress LLC L-Alanine, N-phosphono-, P→6-ester with 2-C-(4-aminopyrrolo[2,1-f]triazin-7-yl)... | 1911579-04-8 | 97.86% | 442.32 | 1 MG
GS-704277 is an alanine metabolite of Remdesivir. It is further hydrolyzed to GA-441524, a compound with antiviral activity. Remdesivir, a nucleoside analogue, is effective against SARS-CoV-2 (COVID-19) infection.
- Alanine metabolite of Remdesivir
- Further metabolized to GA-441524, which exhibits antiviral activity
- Related to Remdesivir, a nucleoside analogue effective against SARS-CoV-2 (COVID-19) infection
- Functions as a drug metabolite
- Involves the metabolic enzyme/protease pathway
AARON CHEMICALS LLC DIMETHYL ISOSORBIDE, 500G
Dimethyl Isosorbide | Purity: 97% | Mol Wt: 174.1944 | 5306-85-4 | MFCD00064828 | 500g
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran solution c
The product is a tetrahydrofuran (THF) SOLUTIONon containing 20%(v/v) 1 2-propanediol. THF a saturated cyclic ester is a water miscible organic solvent. The combustion studies of THF have been reported.
Sigma Aldrich Fine Chemicals Biosciences 2-Methyltetrahydrofuran BioRenewable, anhydrous, >=99%, Inhibitor-free | 96-47-9 | MFCD00005367 | 100ML
2-Methyltetrahydrofuran BioRenewable, anhydrous, >=99%, Inhibitor-free | Purity: >=99% | Mol Wt: 86.13 | 96-47-9 | MFCD00005367 | 100ML