Prenol lipids
Selleck Chemical LLC Glycyrrhizin (NSC 167409) S2302-100mg
Glycyrrhizin (NSC 167409 Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress modulates P38 and P-JNK but not p-ERK signalling Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO)
Apexbio Technology LLC Limonin 1180-71-8 10mM (in 1mL DMSO)
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 100mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Medchemexpress LLC HY-N0892 5mg Medchemexpress, AKBA CAS:67416-61-9 Purity:>98%
Medchemexpress, HY-N0892 5mg AKBA CAS:67416-61-9 AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
TARGETMOL CHEMICALS INC RADDEANIN A 5MG
Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. Raddeanin A (NSC-382873) has moderate inhibitory activity against histone deacetylases (HDACs). Raddeanin A has high antiangiogenic potency antitumor activity. purity: 99%
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.2% | 456.7 g/mol | C30H48O3 | 100 MG
Betulinic acid is a natural pentacyclic triterpenoid (CAS 472-15-1) provided as an analytical reference standard for research and analytical applications. It is used as a qualitative and quantitative standard in method development and validation for HPLC, GC, and MS, and is reported to have biological activities including anti-HIV, anti-malarial, anti-inflammatory, and anti-tumor effects.
- High reported purity for analytical applications.
- Suitable for HPLC, GC, and MS method development.
- Intended for qualitative and quantitative reference standards.
- Supplied as a solid reference material with defined sizes.
- Supports research into multiple biological activities.
AdipoGen Forskolin, 66428-89-5, MFCD00082317, 1 mg
MF: C22H34O7, MW: 410.5, ≥99%, Appearance: White to off-white solid. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator.
Cayman Chemical Betulinic Acid, Purity: ≥97%, CAS: 472-15-1, 50 mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Medchemexpress LLC HY-N0371 5mg Medchemexpress, Pachymic acid CAS:29070-92-6 Purity:>98%
Medchemexpress, HY-N0371 5mg Pachymic acid CAS:29070-92-6 Pachymic acid is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Glycyrrhizic acid (standard) | 1405-86-3 | 97.5% | 10 MG
Glycyrrhizic acid (standard) is an analytical reference material of glycyrrhizic acid intended for method development, calibration, and compound identification in analytical workflows. Supplied as a solid in small mass packages, it is suitable for HPLC and LC-MS reference use. CAS 1405-86-3; molecular weight 822.93 g/mol; formula C42H62O16.
- Intended for analytical applications such as HPLC and LC-MS calibration.
- Provided as a solid reference standard in small mass packs (10 MG).
- Identified by CAS 1405-86-3 and molecular weight 822.93 g/mol.
- Used for quality control and compound identification.
- Batch-specific purity and certificate of analysis available on request.
Medchemexpress LLC Ursonic acid (3-ketoursolic acid) | 6246-46-4 | MFCD09752413 | 99.8% | 454.68 g/mol | C30H46O3 | 10 MG
Ursonic acid (3-ketoursolic acid) is a pentacyclic triterpenoid research reagent reported to have anti-inflammatory and cytotoxic activities. It is supplied as a small-quantity powder for laboratory use and is suitable for biochemical studies, cell-based assays, and synthetic applications.
- HPLC-tested purity suitable for research use.
- Molecular formula C30H46O3 and molecular weight 454.68 g/mol.
- Supplied as a powder for dissolution in common organic solvents.
- Appropriate for in vitro pharmacological and biochemical assays.
Cayman Chemical 23-hydroxy Betulinic Acid, Purity: ≥98%, CAS: 85999-40-2, 1 mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
Apexbio Technology LLC Limonin 1180-71-8 100mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Medchemexpress LLC Lupeol | 545-47-1 | 426.72 | 50 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity. It is a potent androgen receptor (AR) inhibitor and is utilized for cancer research, particularly for prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC).
- Active pentacyclic triterpenoid.
- Anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activity.
- Potent androgen receptor (AR) inhibitor.
- Used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC).