Organic Acids
Medchemexpress LLC TL033 TFA | 2746343-70-2 | 98.1% | 1630.83 | 5 MG
TL033 TFA (HY-147340A) is a chemical compound with CAS number 2746343-70-2 and a molecular weight of 1630.83. This product is supplied as a light yellow to yellow solid with a high purity of 98.1% (HPLC). It requires specific storage conditions to maintain its integrity, ensuring reliability for research applications.
- CAS number: 2746343-70-2
- Purity (HPLC): 98.1%
- Molecular weight: 1630.83
- Appearance: Light yellow to yellow solid
- Recommended storage (solid): -20°C, sealed, away from moisture and light
- Storage in solvent: -80°C (6 months) or -20°C (1 month), sealed, away from moisture and light
Medchemexpress LLC Imperatoxin A TFA | 98.7% | 3758.35 (free base) | 1 MG
Imperatoxin A TFA is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. It acts as a Ca2+-release channels/ryanodine receptors (RyRs) activator, enhancing the influx of Ca2+ from the sarcoplasmic reticulum into the cell.
- Purity of 98.65%
- Molecular weight of 3758.35 (free base)
- Appearance as a white to off-white solid
- Soluble in H2O at ≥ 100 mg/mL
Medchemexpress LLC Thymocartin TFA 5mg | 5MG
Thymocartin TFA is the TFA salt form of Thymocartin (HY-105025) Thymocartin TFA inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals Thymocartin TFA is potential for immunodeficiency diseases research[1 [2
Medchemexpress LLC Dendrotoxin-I TFA | 99.9% | 7149.24 | 500 UG
Dendrotoxin-I TFA is a potent K+ channel blocker effective against voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6, with IC50s ranging from 0.13-50 nM. This neurotoxin holds potential in cancer research, as demonstrated by its significant tumor growth inhibition effect when combined with hyperthermia in nude mice with MCF-7 cells.
- Potent K+ channel blocker
- Effective against voltage-gated potassium channel subunits KV1.1, KV1.2, and KV1.6
- Exhibits neurotoxic properties
- Potential for use in cancer research
- Demonstrated tumor growth inhibition in in vivo studies
Med Vet International Chemistry Reagent Acetic Acid ACS Grade 5% 16 oz 400450 Each
Chemistry Reagent Acetic Acid ACS Grade 5% 16 oz 400450 Each
Electron Microscopy Sciences Veco Square Mesh Oyster Grid D100K/200, Nickel
Veco Grids offer superior handling characteristics. Plus, with a 0.8 mil thickness, Veco Grids are the most rigid grids available. 3.05 mm diameter.
Material: Nickel
Pitch: 250 x 125 µm
Holes: 200 x 85 µm
Bar: 50 x 40 µm
Medchemexpress LLC Spexin (Neuropeptide Q) | 1370290-58-6 | >99.9% | 1619.88 | 5 MG
Spexin (Neuropeptide Q) | 1370290-58-6 | >99.9% | 1619.88 | 5 MG
Medchemexpress LLC QL47B TFA | 96.0% | 992.07 | 5 MG
QL47B TFA is a biotinylated analogue of QL47 (HY-80003), functioning as a potent inhibitor of BTK with an IC50 value of 1.3 μM. It also exhibits anti-tumor activity.
- Potent inhibitor of BTK (IC50 value of 1.3 μM).
- Exhibits anti-tumor activity.
Medchemexpress LLC Clovibactin TFA | 97.1% | 903.08 | 1 MG
Clovibactin TFA is the TFA salt form of Clovibactin (HY-P10027), serving as an antibiotic for drug-resistant bacterial pathogens without detectable resistance. It functions by inhibiting cell wall synthesis, specifically targeting pyrophosphate of peptidoglycan precursors.
- Effective against drug-resistant bacterial pathogens.
- No detectable resistance observed.
- Inhibits cell wall synthesis through a specific mechanism targeting peptidoglycan precursors.
- Demonstrates inhibition of Staphylococcus strains with MICs ranging from 0.125-2 μg/mL in vitro.
- Exhibits a characterized pharmacokinetic profile in mice, including a Cmax of 219.3 μg/mL and a t1/2 of 2 hours following a 20 mg/kg intravenous single dose.
Medchemexpress LLC WP9QY (TFA) | 199999-60-5 | 98.7% | 1340.40 | 25 MG
WP9QY TFA is a biologically active cyclic peptide, serving as a TNF-α Antagonist. It is designed to mimic the critical tumor necrosis factor (TNF) recognition loop on TNF receptor I, preventing interactions of TNF with its receptor. This peptide is a useful template for developing small molecular inhibitors to prevent inflammatory bone destruction and systemic bone loss in rheumatoid arthritis. It is for research use only.
- Biologically active peptide
- TNF-α antagonist
- Mimics critical tumor necrosis factor recognition loop on TNF receptor I
- Prevents TNF interactions with its receptor
- Useful template for small molecular inhibitor development
- Prevents inflammatory bone destruction
- Prevents systemic bone loss in rheumatoid arthritis
- For research use only
Medchemexpress LLC GRL-1720 TFA | 2835511-03-8 | C16H12ClF3N2O4 | 25 MG
GRL-1720 TFA is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 value of 15 μM, demonstrating anti-SARS-CoV2 activity. This product appears as a light brown to brown solid with a purity of 98.94% and is intended for research use only.
- Potent inhibitor of SARS-CoV-2 Mpro
- Demonstrates anti-SARS-CoV2 activity
- EC50 value of 15 μM
- Solid appearance
- Light brown to brown color
- Purity of 98.94%
- Intended for research use only
Medchemexpress LLC HDAC11-IN-1 TFA | 99.3% | 995.15 | 1 MG
HDAC11-IN-1 TFA is a selective macrocyclic inhibitor of HDAC11 with a Ki of 40 nM. It exhibits good cell permeability and can inhibit the expression of YAP1 and SOX2. The product is for research purposes only and is not sold to patients.
- Selective macrocyclic inhibitor of HDAC11 with a Ki of 40 nM.
- Exhibits good cell permeability.
- Can inhibit the expression of YAP1 and SOX2.
- For research purposes only.
Medchemexpress LLC SAH-SOS1A TFA | 2896737-31-6 | 96.6% | 2301.55 | 1 MG
SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. It binds to wild-type and mutant KRAS with nanomolar affinity, directly and independently blocking nucleotide association. This compound impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS.
- Peptide-based SOS1/KRAS protein interaction inhibitor
- Binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, Q61H) with nanomolar affinity (EC50=106-175 nM)
- Directly and independently blocks nucleotide association
- Impairs cancer cell viability
- Blocks ERK-MAPK phosphosignaling cascade downstream of KRAS
Medchemexpress LLC Wp9qy Tfa | 99.4% | 1340.40 | 5 MG
WP9QY TFA is a biologically active cyclic peptide designed as a TNF-α antagonist. It mimics the critical tumor necrosis factor (TNF) recognition loop on TNF receptor I, thereby preventing interactions of TNF with its receptor. This makes it a useful template for developing small molecular inhibitors to prevent inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.
- Acts as a TNF-α antagonist
- Designed to mimic TNF recognition loop on TNF receptor I
- Prevents TNF interactions with its receptor
- Useful for developing inhibitors for inflammatory bone destruction
- Helps prevent systemic bone loss in rheumatoid arthritis
Medchemexpress LLC Huwentoxin-IV TFA | 105856-78-4 | 99.04% | 4099.71 | 5 MG
Huwentoxin-IV TFA is a highly potent and selective blocker of neuronal voltage-gated sodium channels. It specifically inhibits NaV1.7 activity in human DRG neurons.
- Potent and selective sodium channel blocker
- Inhibits neuronal NaV1.7, NaV1.2, NaV1.3, and NaV1.4 channels
- IC50 of 2.9 nM for inhibiting NaV1.7-mediated currents
- Reduces NaV1.7 current amplitude by 50% at 0.5 nM