Organic Acids
U.S. Pharmacopeia Formic Acid (1.2 mL/ampule; 3 ampules) | 64-18-6 | MFCD00003297
Formic Acid (1.2 mL/ampule; 3 ampules) | Mol Wt: 46.025 | 64-18-6 | MFCD00003297 |
eMolecules Ambeed / Ammonium formate / 25g / 506390793 / A414767 / / 540-69-2 / MFCD00013103 / 63.056 / CH5NO2
Ambeed / Ammonium formate / 25g / 506390793 / A414767 / / 540-69-2 / MFCD00013103 / 63.056 / CH5NO2
Medchemexpress LLC DL-01 formic | 2964513-44-6 | 98.5% | 1144.30 g/mol | C56H73N9O15S | 1 MG
DL-01 formic is a drug-linker conjugate intended for research use in the synthesis of antibody-drug conjugates (ADCs). Supplied as a white to light yellow solid, it has high purity and requires ultra-low temperature storage to preserve stability.
- Drug-linker conjugate for antibody-drug conjugate (ADC) synthesis.
- White to light yellow solid physical form.
- Purity approximately 98.5%.
- Molecular weight 1,144.30 g/mol.
- CAS number 2964513-44-6.
- Stored at -80°C and protected from light under inert gas.
- Available in small milligram quantities for research use.
Medchemexpress LLC CBI1 formic | 461.40 | C16H21BrN4O3S2 | 10 MG
CBI1 formic is a covalent small-molecule inhibitor of BAX that selectively derivatizes the protein at cysteine 126 (C126), preventing BAX activation. Supplied for research use, structural and storage information is provided by the manufacturer.
- Covalent BAX inhibitor that derivatizes C126.
- Inhibits BAX activation induced by ligands or point mutations.
- Offered as a solid with sealed, moisture-free storage recommendations.
- Molecular formula C16H21BrN4O3S2; molecular weight 461.40.
- Available in small research pack sizes, including 10 mg.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | C26H25N5O4S | 10MG
Ro 31-8220 formic is a small-molecule research reagent that acts as a potent, cell-permeable inhibitor of protein kinase C (PKC) and several other kinases. It is used in biochemical and cellular studies to probe PKC-dependent signaling, kinase selectivity, and downstream pathway effects such as JNK activation and c-Jun induction.
- Potent PKC inhibition with low-nanomolar IC50s.
- Inhibits multiple kinases for broad pathway interrogation.
- Cell-permeable for use in cellular assays.
- High purity solid with characteristic orange to red color.
- Stable when stored sealed at -20°C; in solvent can be stored at -80°C for extended periods.
- Available in small milligram pack sizes suitable for research use.
Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 10 MM * 1 ML
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It is intended for research use only and available in various forms, including solid and as a 10 mM * 1 mL solution in DMSO.
- Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
- Intended for research use only
- Purity of 99.91%
- Molecular weight of 403.56
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL (247.79 mM)
- Induces a dose-dependent decrease in circulating lymphocytes in vivo
- Achieves a maximum concentration of 4 μM in rats at 2 hours post-dose with a half-life of 8 hours
- Related to respiratory, inflammatory, and pulmonary diseases, and lung fibrosis
- Affects inflammation/immunology, GPCR/G protein, and LPL receptor signaling pathways
Medchemexpress LLC MRTX-EX185 formic | 2988148-70-3 | 97.23% | C34H35FN6O4 | 1 MG
MRTX-EX185 formic is a potent KRAS (G12D) inhibitor (IC50 of 90 nM) that binds to both GDP-loaded and active GNP states of KRAS. It exhibits broad-spectrum binding properties and is used for studying various RAS-driven tumors, such as pancreatic cancer.
- Potent KRAS (G12D) inhibitor with IC50 of 90 nM
- Binds to GDP-loaded and active GNP states of KRAS and KRAS (G12D)
- Exhibits broad-spectrum binding properties including for KRAS WT, G12C, Q61H, G13D, and HRAS
- Suppresses cell proliferation in KRAS (G12D)-driven SW-1990 pancreatic cancer cells (IC50 = 70 nM)
- Non-toxic to non-KRAS-dependent HEK293 cells
- Significantly inhibits ERK phosphorylation in KRAS(G12C)-driven cell lineages
Medchemexpress LLC Slb1122168 formic | 2999629-17-1 | 99.9% | 403.56 | C23H37N3O3 | 10 MG
SLB1122168 formic is a research-stage small molecule that inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release. It has reported in vitro potency and is supplied for laboratory research with recommended storage and handling per the Safety Data Sheet.
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 1 ML
PKCiota-IN-2 formic is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. It also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
- Potent PKCiota inhibitor with an IC50 of 2.8 nM.
- Also inhibits PKC-α with an IC50 of 71 nM.
- Inhibits PKC-ε with an IC50 of 350 nM.
Medchemexpress LLC CBI1 formic | 461.40 | 100 MG
CBI1 formic is a covalent BAX inhibitor that selectively derivatizes BAX at C126. It inhibits BAX activation triggered by ligands or point mutagenesis, blocking t-2-hex lipidation and oligomerization of BAX.
- Inhibits BAX activation induced by BH3 ligands
- Blocks t-2-hex lipidation and oligomerization
- For research use only
Medchemexpress LLC GZD856 formic | 2804039-78-7 | 95.4% | 578.58 g/mol | C30H29F3N6O3 | 1 ML
GZD856 formic is a research-grade small-molecule inhibitor supplied as a 10 mM solution in DMSO for laboratory use. It is provided as the formic salt in a 1 mL vial and is intended for in vitro and exploratory studies needing a pre-dissolved, characterized compound.
- Pre-formulated 10 mM solution for immediate use.
- Supplied in a 1 mL vial for small-scale experiments.
- Formic salt form to enhance solubility and stability.
- Purity determined by HPLC, reported at 95.36%.
- Molecular weight 578.58 g/mol; formula C30H29F3N6O3.
Medchemexpress LLC CCT367766 formic | 98.1% | 992.42 | 10 MG
CCT367766 formic is a potent, third-generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe. It effectively depletes pirin protein expression at low concentrations and provides a potential chemical tool for studying this largely unexplored protein.
- Exhibits moderate affinity for the CRBN-DDB1 complex with an IC50 of 490 nM.
- Demonstrates good affinity for recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively.
- Depletes pirin protein in SK-OV-3 human ovarian cancer cells in a time-dependent manner.
- Rescues pirin expression from pretreatment of chlorobisamide in SK-OV-3 cells.