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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
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A nonpeptide substrate of proteases and deiminases; has been used as a substrate for the quantification of papain, carboxypeptidase B, PAD2, and PAD4 activities
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N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
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KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hindering high-salt-induced NFAT5 and its target gene expressions. KRN2 also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence in the upstream site of Nfat5 exon 1.
Effectively suppresses AIA in which innate immune cells play a predominant role.
Effectively suppresses CIA as well as AIA in mice.
Decreases the production of pro-inflammatory cytokines and autoantibodies.
Reduces macrophage infiltration.
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N6-benzoyl-2'-deoxyadenosine monohydrate is a protected nucleoside analog supplied as a monohydrate solid for research use. It serves as a building block in oligonucleotide and nucleotide chemistry and is characterized for purity and composition to support analytical and synthetic workflows.
Protected adenosine derivative for nucleotide synthesis.
Monohydrate solid, white to off-white in appearance.
High purity (98.0%) for reproducible results.
Available in multiple package sizes, including 10 G, for scale flexibility.
Documented molecular weight and formula for formulation and analysis.
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Mepenzolate bromide (CAS 76-90-4) is a synthetic quaternary ammonium compound that functions as a muscarinic acetylcholine receptor antagonist By inhibiting parasympathetic neural transmission it reduces gastric secretion and gastrointestinal motility Mepenzolate bromide is generally supplied as a white to light cream powder with high solubility in methanol limited solubility in water and chloroform and minimal solubility in ether This compound is widely employed in research investigating modulation of cholinergic signaling gastrointestinal physiology and autonomic pharmacology and serves as a tool compound for studying antimuscarinic mechanisms in vitro and in vivo
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N6-benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analog used in biochemical research and oligonucleotide synthesis. Supplied as a solid monohydrate, it is used in diagnostic and analytical workflows that require modified nucleosides.
Nucleoside analog used in oligonucleotide synthesis and nucleoside research.
Monohydrate solid form for easier handling and storage.
High purity (98.0%) suitable for research applications.
Chemical formula C17H19N5O5; molecular weight 373.36.
Available in common laboratory pack sizes, including 25 G.
Applicable in diagnostic and analytical workflows requiring DNA binding or modification.
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Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist with potential for research into chronic obstructive pulmonary disease (COPD). It has shown potent antagonism of human muscarinic receptors preclinically, with a long residence time at M3 receptors, suggesting potential for sustained bronchodilation. Early clinical studies have indicated low systemic bioavailability and a favorable safety profile.
Long-acting muscarinic antagonist
Potential for chronic obstructive pulmonary disease (COPD) research
Exhibits potent antagonism of human muscarinic receptors
Long residence time at M3 receptors for sustained bronchodilation
Low systemic bioavailability
Favorable safety profile
Rapidly hydrolyzed in human plasma
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KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It is for research use only and not sold to patients.
Selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6.
Dose-dependently inhibits the NF-κB p65 binding to Nfat5 promoter 1.
Directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
Effectively suppresses AIA and CIA in mice.
Decreases the production of pro-inflammatory cytokines and autoantibodies.
Reduces macrophage infiltration.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More