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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist with potential for research into chronic obstructive pulmonary disease (COPD). It has shown potent antagonism of human muscarinic receptors preclinically, with a long residence time at M3 receptors, suggesting potential for sustained bronchodilation. Early clinical studies have indicated low systemic bioavailability and a favorable safety profile.
Long-acting muscarinic antagonist
Potential for chronic obstructive pulmonary disease (COPD) research
Exhibits potent antagonism of human muscarinic receptors
Long residence time at M3 receptors for sustained bronchodilation
Low systemic bioavailability
Favorable safety profile
Rapidly hydrolyzed in human plasma
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4-(2-Bromoacetyl)benzonitrile is a compound that can be used for the synthesis of STA-5312. STA-5312 is a potent and orally active microtubule inhibitor. This product is intended for research use only.
Solid with an off-white to yellow color
Can be used for chemical synthesis
Research use only
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Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract. It effectively relieves pain, diarrhea, and intestinal discomfort, providing good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients.
Inhibits GM-CSF or CXCL1/CXCL2 induced neutrophil migration and ROS production.
Inhibits GM-CSF induced expression of cytokines (IL-1β, IL-6, and TNF-α) in primed neutrophils.
Inhibits the contractile response to ACh or KCl in colonic circular muscle.
Inhibits excessive systemic inflammation in Lipopolysaccharide-induced mice.
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N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine can be used as an intermediate. It is for research use only and not sold to patients. The product appears as a white to off-white solid.
Used as an intermediate.
Solid appearance.
White to off-white color.
Available for research purposes.
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1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog, which exhibits broad antitumor activity by targeting indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
Purine nucleoside analog
Broad antitumor activity
Targets indolent lymphoid malignancies
Inhibits DNA synthesis
Induces apoptosis
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Benzoyl coenzyme A (Benzoyl CoA) is an intermediate in the CoA-dependent epoxide pathway synthesized from benzoate in the presence of the enzyme benzoate-CoA ligase. It is further converted to 2 3-epoxybenzoyl-CoA and this step is catalyzed by benzoyl-CoA reductase (BoxA) and benzoyl-CoA oxygenase(BoxB).
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Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
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Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
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Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
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Chemical. CAS 518-67-2. Formula C20H18BrN3. MW 380.28. Synthetic. Intercalating probe for nucleic acids. Other applications include the determination of cationic surfactants.
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Chemical. CAS 155862-95-6. Formula C27H22BrN3O6. MW 564.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance.
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Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
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Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Tarloxotinib bromide (TH-4000) is an irreversible inhibitor of EGFR/HER2. Purity 97.15%
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