Benzenoids
Medchemexpress LLC 1,4-Bis(diphenylphosphino)butane | 7688-25-7 | 426.47 | 50 G
1,4-Bis(diphenylphosphino)butane is a biochemical reagent for life science-related research. It serves as a ligand in various reactions, including palladium(0)-catalyzed acylcyanation of arylacetylenes and deprotection of allyloxycarbamates. It also finds use in organometallic chemistry, alkylation, and isomerization reactions.
- Used in Suzuki, Heck, Negishi, and Sonogashira coupling reactions
- Acts as a ligand for alkylations and isomerization reactions
- Essential in organometallic chemistry
Medchemexpress LLC Rilmazafone hydrochloride | 85815-37-8 | 511.79 | 100 MG
Rilmazafone hydrochloride is a benzodiazepine (omega) ligand, intended for research use only.
- Solid storage at 4°C
- Sealed storage, away from moisture
- In solvent storage at -80°C for 6 months
- In solvent storage at -20°C for 1 month
Medchemexpress LLC Levacetylleucine | 1188-21-2 | C8H15NO3 | 10 G
Levacetylleucine (N-acetyl-L-leucine) is an orally bioavailable and brain-penetrant compound, derived from the amino acid Leucine through acetylation. It is the active form of N-acetyl-leucine (NAL). This compound offers several benefits and features for research:
- Attenuates neuronal death and neuroinflammation in the cortical tissue of mice.
- Potentially improves lysosomal and metabolic dysfunction.
- Improves compensation of postural symptoms after unilateral chemical labyrinthectomy (UL) in rats.
- Shows promise for research in neurological manifestations of Niemann-Pick disease type C, traumatic brain injury, and neurodegeneration prevention.
Medchemexpress LLC Chenodeoxycholic Acid | 474-25-9 | 99.9% | C24H40O4 | 500 MG
Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. This product is intended for research use only.
- Activates nuclear receptors (FXR) involved in cholesterol metabolism.
- Inhibits 11 beta HSD2.
- Stimulates Ishikawa cell growth by inducing Cyclin D1 protein and mRNA expression.
- Induces LDL receptor mRNA levels approximately 4-fold.
- Activates C/EBPβ and AMP-activated protein kinase (AMPK).
Medchemexpress LLC 2-(Hydroxy(4-phenoxyphenyl)methylene)malononitrile | 330792-68-2 | 95.1% | C16H10N2O2 | 500 MG
2-(Hydroxy(4-phenoxyphenyl)methylene)malononitrile is a chemical compound primarily utilized as a drug intermediate in the synthesis of various active pharmaceutical compounds.
- Molecular weight: 262.27
- Appearance: Solid
- Storage: Powder at -20°C for 3 years or 4°C for 2 years; in solvent at -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC Chenodeoxycholic Acid-d4 | 99102-69-9 | 99.9% | C24H36D4O4 | 5 MG
Chenodeoxycholic Acid-d4 is a deuterium-labeled primary bile acid. It is a hydrophobic compound that activates nuclear receptors (FXR) involved in cholesterol metabolism, and is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 4-Fluoro-5-hydroxy-2-methylindole | 288385-88-6 | 98.88% | C9H8FNO | 5 G
4-Fluoro-5-hydroxy-2-methylindole is a drug intermediate for the synthesis of various active compounds. It is supplied as a white to off-white solid with a purity of 98.88%.
- Drug intermediate for synthesis of active compounds
- Available in multiple package sizes
- Solid appearance
- White to off-white color
- For research use only
![Medchemexpress LLC 1,5-Methano-8H-pyrido[1,2-a]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-methyl-,(1R,5S)- | 486-86-2 | 204.27 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000389731.png-250.jpg)
Medchemexpress LLC 1,5-Methano-8H-pyrido[1,2-a]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-methyl-,(1R,5S)- | 486-86-2 | 204.27 | 1 ML
N-Methylcytisine (Caulophylline) is a tricyclic quinolizidine alkaloid recognized for its hypoglycaemic, analgesic, and anti-inflammatory properties. It acts as a selective ligand for nicotinic acetylcholine receptors in the central nervous system, showing a high affinity (Kd = 50 nM) for nAChR from squid optical ganglia. This compound is intended for research use only.
- Exhibits hypoglycaemic, analgesic and anti-inflammatory activities.
- Acts as a selective ligand of nicotinic receptors of acetylcholine.
- Shows high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR).
- Ameliorates symptoms of DSS-induced colitis in mouse models.
- Reduces concentrations of TNF-α, IL-1β, and IL-6.
- Inhibits p-NK-κB p65 expression in colon tissue.