Hydrocarbons
Sigma Aldrich Fine Chemicals Biosciences (Iodomethyl)cyclopentane contains copper as stabilizer | 27935-87-1 | MFCD03453190 | 1g
(Iodomethyl)cyclopentane contains copper as stabilizer | 95% | MW: 210.06 | 27935-87-1 | MFCD03453190 | 1g
Medchemexpress LLC TAMRA alkyne, 5-isomer | 945928-17-6 | 96.6% | 467.52 g/mol | C28H25N3O4 | 10 MG
TAMRA alkyne, 5-isomer is a red-fluorescent tetramethylrhodamine derivative bearing a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC) labeling of biomolecules. Supplied as a solid small-molecule reagent, it is suitable for fluorescence labeling, enrichment, in-gel detection, and analytical identification.
Medchemexpress LLC ML162-yne | 2883115-46-4 | 99.1% | 501.42 g·mol⁻¹ | C25H22Cl2N2O3S | 10 MG
ML162-yne is a GPX4-inhibitor affinity probe designed for click-chemistry applications. The molecule contains an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling or capturing target-engaged proteins. It is supplied as a high-purity solid or as a DMSO solution and is intended for research use only.
- Enables selective labeling via copper-catalyzed azide-alkyne cycloaddition.
- Functions as an affinity probe for glutathione peroxidase 4 (GPX4).
- Supplied with high purity for reliable experimental results.
- Available as solid and ready-to-use DMSO solution formats.
- Stable under recommended storage conditions for long-term use.
Medchemexpress LLC 8-bromooct-1-yne | 81216-13-9 | MFCD20621358 | 189.09 | C8H13Br | 500 MG
8-Bromooct-1-yne is an organobromide reagent containing a terminal alkyne and a bromide leaving group. It is used as a synthetic building block in organic chemistry and for bioconjugation workflows such as copper-catalyzed azide-alkyne cycloaddition (click chemistry). Store under nitrogen at 4°C; in solution, keep at -80°C (up to 6 months) or -20°C (up to 1 month). CAS: 81216-13-9; formula: C8H13Br; MW: 189.09.
- Terminal alkyne for conjugation and cross-coupling reactions.
- Bromide leaving group enables nucleophilic substitution.
- Suitable for copper-catalyzed click chemistry with azide partners.
- Supplied in small-scale quantities for research applications.
- Store under inert atmosphere to preserve stability.
Medchemexpress LLC 8-bromooct-1-yne | 81216-13-9 | MFCD20621358 | 189.09 g/mol | C8H13Br | 100 MG
8-Bromooct-1-yne is a brominated terminal alkyne reagent used in organic synthesis and copper-catalyzed click chemistry. It offers both a reactive alkyne for azide coupling and a bromide leaving group for substitution, supplied in small research-scale quantities and requiring inert storage.
- Terminal alkyne reagent for organic synthesis and click chemistry.
- Contains a bromide leaving group for nucleophilic substitution.
- Molecular formula C8H13Br; molecular weight 189.09 g/mol.
- Suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Available in small research-scale pack sizes for laboratory use.
- Store under nitrogen at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Bis(choline)tetrathiomolybdate | 649749-10-0 | 98.0% | 432.56 g/mol | C10H28MoN2O2S4 | 10 MG
ATN-224 (bis(choline)tetrathiomolybdate) is an orally active Cu2+/Zn2+-dependent superoxide dismutase 1 (SOD1) inhibitor used in research to modulate copper-dependent enzymatic activity and angiogenesis. It inhibits SOD1 activity in endothelial and tumor cells and has been characterized in cellular and in vivo models.
- Orally active Cu2+/Zn2+ SOD1 inhibitor with reported IC50 ~17.5 nM in endothelial cells.
- High affinity copper binder, showing selectivity against Ca, Fe, Mg, Zn, and Mn up to 1 mM.
- Inhibits proliferation of HUVEC cells (IC50 ~1.4 μM) and purified SOD1 (IC50 ~0.33 μM after 24 h).
- Time-dependent SOD1 inhibition, reaching maximal effect at ~16 hours.
- Demonstrated inhibition of angiogenesis in Matrigel plug models in mice.
Medchemexpress LLC MD-224 10mM | 10MM 1ML
MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept MD-224 consists of ligands for Cereblon and MDM2 MD-224 induces rapid degradation of MDM2 at concentrations 1 nM in human leukemia cells and achieves an IC50 value of 1 5 nM in inhibition of growth of RS4 11 cells MD-224 has the potential to be a new class of anticancer agent[1] MD-224 is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC 18-azido-stearic acid | 1529763-58-3 | MFCD35066654 | ≥95.0% | 325.49 g/mol | C18H35N3O2 | 10 MG
18-Azido-stearic acid is an azide-functionalized long-chain fatty acid used as a hydrophobic bioconjugation linker for click chemistry. It enables efficient attachment of lipophilic tags or cargos to biomolecules via copper-catalyzed or strain-promoted azide-alkyne cycloaddition, and is supplied as a stable powder for laboratory research use.
- Contains a terminal azide functional group for click reactions.
- Compatible with CuAAC and SPAAC bioconjugation methods.
- Hydrophobic stearic backbone facilitates membrane incorporation or lipophilic tagging.
- Solid powder form with recommended storage for long-term stability.
- Available in small milligram pack sizes suitable for research applications.
Medchemexpress LLC 8-bromooct-1-yne | 81216-13-9 | MFCD20621358 | 189.09 g·mol⁻¹ | C8H13Br | 1 G
8-Bromooct-1-yne is a brominated terminal alkyne reagent used as a synthetic building block in organic synthesis and chemical biology research. It combines a terminal alkyne for click-type reactions with a bromide leaving group for nucleophilic substitution, enabling installation of alkynyl linkers and chain elaboration in probe and linker synthesis.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Bromide functions as a good leaving group for nucleophilic substitution and chain modification.
- Suitable as a building block for probes, tags, and linker or PROTAC synthesis.
- Available in small laboratory quantities for research use.
- Handle under inert atmosphere and store cold according to handling guidelines.
Medchemexpress LLC 8-bromooct-1-yne | 81216-13-9 | MFCD20621358 | 189.09 g/mol | C8H13Br | 250 MG
8-Bromooct-1-yne is a terminal alkyne bearing a bromide substituent used as a synthetic building block for organic synthesis and chemical biology. It participates in alkyne-based coupling and substitution reactions, enabling installation of functional groups or linkers in small-molecule synthesis and bioconjugation.
- Terminal alkyne with a reactive bromide group.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (click chemistry) and cross-coupling reactions.
- Useful as an alkylating building block for functionalization and chain extension.
- Provided as a 250 mg research reagent; store under inert atmosphere at low temperature for stability.
- Molecular formula C8H13Br; molecular weight 189.09 g/mol.
- Purity not specified on the manufacturer product page.
Medchemexpress LLC Tamra alkyne, 5-isomer | 945928-17-6 | MFCD29912899 | 96.6% | 467.52 g/mol | C28H25N3O4 | 50 MG
TAMRA alkyne, 5-isomer is an alkyne-derivatized tetramethylrhodamine fluorescent probe for bioorthogonal labeling by click chemistry. It is designed for selective conjugation to azide-bearing biomolecules and enables enrichment, in-gel fluorescence detection, and identification of modified proteins.
- Alkyne functional group for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN reagents.
- Enables enrichment and in-gel fluorescence detection of labeled proteins.
- High purity (~96.6%) with characterized molecular weight and formula.
- Supplied as the single 5-isomer to ensure consistent labeling performance.
- Available in multiple package sizes for research use.
Medchemexpress LLC Tamra azide, 5-isomer | 825651-66-9 | 98.6% | 512.56 | C28H28N6O4 | 10 MG
TAMRA azide, 5-isomer is a tetramethylrhodamine-based fluorescent azide reagent designed for conjugation via click chemistry. The azide functionality enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), allowing efficient labeling of biomolecules for fluorescence detection and imaging applications.
- Fluorescent tetramethylrhodamine dye with orange emission.
- Azide functional group enables CuAAC and SPAAC conjugation reactions.
- Suitable for labeling proteins, peptides, nucleic acids, and small molecules.
- High purity (98.6%) for reliable analytical and imaging results.
- Solid material for preparation of concentrated stock solutions in organic solvents.
- Molecular weight 512.56; molecular formula C28H28N6O4.