Organoheterocyclic compounds
1-(Trifluoroacetyl)piperidine 98.0+%, TCI America™
CAS: 340-07-8 Molecular Formula: C7H10F3NO Molecular Weight (g/mol): 181.158 MDL Number: MFCD00466213 InChI Key: BCJUMGSHTLYECD-UHFFFAOYSA-N PubChem CID: 5181830 IUPAC Name: 2,2,2-trifluoro-1-piperidin-1-ylethanone SMILES: C1CCN(CC1)C(=O)C(F)(F)F
2-Methyl-8-nitroquinoline 98.0+%, TCI America™
CAS: 881-07-2 Molecular Formula: C10H8N2O2 Molecular Weight (g/mol): 188.19 MDL Number: MFCD00006764 InChI Key: UHPGVDHXHDPYQP-UHFFFAOYSA-N PubChem CID: 13433 IUPAC Name: 2-methyl-8-nitroquinoline SMILES: CC1=CC=C2C=CC=C(C2=N1)[N+]([O-])=O
1,7-Octadiene Diepoxide 97.0+%, TCI America™
CAS: 2426-07-5 Molecular Formula: C8H14O2 Molecular Weight (g/mol): 142.20 MDL Number: MFCD00005155 InChI Key: LFKLPJRVSHJZPL-UHFFFAOYNA-N Synonym: 1,2,7,8-diepoxyoctane,1,2:7,8-diepoxyoctane,1,7-octadiene diepoxide,oxirane, 2,2'-1,4-butanediyl bis,1,2-epoxy-7,8-epoxyoctane,2,2'-1,4-butanediyl bisoxirane,1,4-di oxiran-2-yl butane,octane, 1,2:7,8-diepoxy,2-4-oxiran-2-yl butyl oxirane,ccris 963 PubChem CID: 17048 ChEBI: CHEBI:23705 IUPAC Name: 2-[4-(oxiran-2-yl)butyl]oxirane SMILES: C1C(O1)CCCCC2CO2
4-Methyl-7-morpholino-8-azacoumarin 98.0+%, TCI America™
CAS: 57980-07-1 Molecular Formula: C13H14N2O3 Molecular Weight (g/mol): 246.266 MDL Number: MFCD18803635 InChI Key: UGHFUCYBDDPFJX-UHFFFAOYSA-N Synonym: 4-Methyl-7-morpholino-2H-pyrano[2,3-b]pyridin-2-one PubChem CID: 93904 IUPAC Name: 4-methyl-7-morpholin-4-ylpyrano[2,3-b]pyridin-2-one SMILES: CC1=CC(=O)OC2=C1C=CC(=N2)N3CCOCC3
Apexbio Technology LLC EGFR Inhibitor 879127-07-8 25mg
EGFR Inhibitor (CAS 879127-07-8) is a cell-permeable pyrimidine small molecule that selectively targets the epidermal growth factor receptor (EGFR) tyrosine kinase By inhibiting EGFR kinase activity with an IC50 of 21 nM this compound disrupts receptor autophosphorylation and downstream signaling It also demonstrates inhibitory activity against EGFR mutants L858R and L861Q with IC50 values of 63 nM and 4 nM respectively Inhibition of EGFR leads to altered expression of apoptotic regulators promoting apoptosis in tumor cells EGFR Inhibitor is valuable for investigating EGFR-dependent cellular processes and mechanisms underlying cancer progression or resistance
Medchemexpress LLC Nystose | 13133-07-8 | 666.58 | 100 MG
Nystose is a tetrasaccharide formed by two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose. It exhibits prebiotic, immunomodulatory, and metabolism-regulating activities, and also promotes bone mineralization.
- Exhibits prebiotic, immunomodulatory, and metabolism-regulating activities.
- Promotes bone mineralization by activating the Wnt/β-catenin signaling pathway.
- Can be fermented by lactobacilli (L. intestinalis and L. reuteri).
- Promotes the proliferation of lactobacilli.
- Increases the activity of alkaline phosphatase (ALP).
- Promotes the proliferation of bone marrow stromal cells (BMSCs).
Medchemexpress LLC Remibrutinib | 1787294-07-8 | 99.8% | 1 MG
Remibrutinib is a potent and orally active Bruton Tyrosine Kinase (BTK) inhibitor with an IC50 value of 1 nM. It inhibits BTK activity with an IC50 value of 0.023 μM in blood and has potential for the treatment of Chronic Urticaria (CU).
- Potent and orally active BTK inhibitor
- Inhibits BTK activity with an IC50 of 1 nM
- Has potential for chronic urticaria treatment
- Purity of 99.8%
- Molecular weight of 507.53
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC Remibrutinib | 1787294-07-8 | 99.8% | 1 ML
Remibrutinib is a potent and orally active Bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. It inhibits BTK activity with an IC50 value of 0.023 μM in blood. This compound has the potential for Chronic Urticaria (CU) treatment.
- Potent and orally active Bruton tyrosine kinase (BTK) inhibitor
- Inhibits BTK activity with an IC50 value of 1 nM
- Inhibits BTK activity in blood with an IC50 value of 0.023 μM
- Potential for Chronic Urticaria (CU) treatment
Medchemexpress LLC Stemazole 1mg | 317337-07-8 | 1 MG
Stemazole is a small-molecule stem cell survival protective agent that promotes the survival and proliferation of human embryonic stem cells. It is supplied as a high-purity research reagent suitable for cellular assays and in vitro studies.
- Promotes stem cell survival and proliferation.
- High purity: 99.96%.
- Chemical formula C9H9N5OS2; molecular weight 267.34 g/mol.
- Provided as a solid suitable for preparation of stock solutions.
- Storage: store long-term at -20°C under inert gas; in solution, keep at -80°C for up to 6 months or -20°C for up to 1 month.
- Intended for research use in stem cell and cellular assays.
Medchemexpress LLC Nystose | 13133-07-8 | 666.58 | 1 ML
Nystose is a tetrasaccharide composed of two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose. It exhibits prebiotic, immunomodulatory, and metabolism-regulating activities. Nystose promotes bone mineralization by activating the Wnt/β-catenin signaling pathway.
- Exhibits prebiotic, immunomodulatory, and metabolism regulating activities.
- Promotes bone mineralization by activating the Wnt/β-catenin signaling pathway.
- Can be fermented by lactobacilli (L. intestinalis and L. reuteri) and promotes their proliferation.
- Increases the activity of ALP and the proliferation of BMSCs.
- Enhances intestinal IgA secretion and modulates systemic immune responses.
- Improves bone density and microstructure in mouse models.
Medchemexpress LLC Stemazole 5mg | 317337-07-8 | 5 MG
Stemazole is a small-molecule research reagent reported to promote stem cell survival and proliferation in vitro. It is supplied as a high-purity solid for assay development and biological studies; follow supplier storage recommendations.
Medchemexpress LLC Sesamolin | 526-07-8 | 370.35 | 1 ML
Sesamolin, isolated from Sesamum indicum, possesses antioxidative activity and inhibits lipid peroxidation. It also demonstrates a neuroprotective effect. Sesamolin potently inhibits MAPK cascades by preventing the phosphorylation of JNK, p38 MAPKs, and caspase-3, but not ERK-MAPK expression. It is orally active.
- Antioxidative activity
- Inhibits lipid peroxidation
- Shows neuroprotection effect
- Potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3
- Orally active
Medchemexpress LLC Griseofulvin | 126-07-8 | 98.9% | 352.77 | 1 ML
Griseofulvin is an orally active antifungal antibiotic with antitumor activity. It induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also exhibits cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand syndrome.
- Orally active antifungal antibiotic
- Exhibits antitumor activity
- Induces apoptosis in cancer cells
- Induces G2/M cell cycle arrest in cancer cells
- Exhibits cardiovascular modulatory activity
- Reduces angina pectoris
- Relieves hand artery spasm
- Relieves peripheral vascular diseases
Medchemexpress LLC Azd-0284 | 2101291-07-8 | 99.9% | 10 MG
AZD-0284 is a selective inverse agonist of the retinoic acid receptor-related orphan receptor γ (RORγ), used as a research tool to study Th17-mediated inflammation and autoimmune disease pathways.
- Selective inverse agonist of RORγ suitable for in vitro and preclinical studies.
- High reported purity (99.9%) for consistent experimental results.
- Available in small-mass formats and DMSO solution for formulation flexibility.
- Documented molecular formula C21H18F6N2O5S and molecular weight 524.43 g/mol.
- Analytical data (e.g., LCMS, COA) reported to support compound identity.
Medchemexpress LLC Griseofulvin | 126-07-8 | 98.85% | 352.77 | 50 MG
Griseofulvin (Standard) is the analytical standard of Griseofulvin. This product is intended for research and analytical applications, and is used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Used in qualitative, quantitative and methodological research experiments
- Suitable for HPLC, GC, and MS applications