Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. It is intended to interrupt severe oral mucositis pathogenesis, to reduce the duration, incidence, and severity of radiation-induced oral mucositis.
- Potent superoxide dismutase mimetic
- Rapidly and specifically converts O2*- to hydrogen peroxide (H2O2)
- Arrests the initiation of the superoxide cascade
- Used for research of severe oral mucositis (SOM) and cancer
- Intended to reduce duration, incidence, and severity of radiation-induced oral mucositis in vivo
- Appearance: Solid, Light yellow to brown