Cytochrome P450 2E1 Antibody (YA2302) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Cytochrome P450 2E1. It is for research use only and demonstrates endogenous sensitivity. This antibody is supplied as a liquid formulation in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide, and 50% glycerol.
- Involved in fatty acid metabolism and potentially xenobiotic oxidative metabolism.
- Catalyzes hydroxylation of carbon-hydrogen bonds, specifically at the omega-1 position of saturated fatty acids.
- Subcellular localization includes endoplasmic reticulum membrane, microsome membrane, and mitochondrion inner membrane.
- Application in western blot (WB) with a dilution ratio of 1:500-1:1000.
- Species reactivity includes human, mouse, and rat.
- Immunogen is a synthesized peptide derived from human CYP2E1 aa52-114.