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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6. purity: 99%
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3',4'-Tetramethylene-α-pyrrolidinobutiophenone hydrochloride is a synthetic research chemical classified as a drug derivative and intended for laboratory research use only. It is supplied as a white to off-white solid and is characterized by high purity according to manufacturer analytical data. Documentation such as a certificate of analysis and safety data sheet are provided.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Calcium channel-modulator-1 is a calcium channel-modulator (IC500.8 uM) with specialisation to block aortic constriction. purity: 99%
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An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide; selective for COX-2 over COX-1 (IC50 = >1,000 µM); inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg; reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg
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GPR120 modulator 2 is a small-molecule research compound that modulates the free fatty acid receptor GPR120 and is intended for in vitro pharmacology and metabolic signaling studies.
Targets the free fatty acid receptor GPR120.
Molecular formula C20H18ClNO3S and molecular weight 387.88.
CAS number 1050506-87-0 for unambiguous identification.
High purity (97.1%) suitable for research applications.
Available in small pack sizes, including 10 mg.
Storage: powder at -20°C for long-term stability, 4°C short term; in solvent store at -80°C.
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IL-17 modulator 3 is an IL-17 modulator that can be used for the research of inflammation, cancer, and autoimmune diseases. This product is for research use only and not sold to patients.
Used for research of inflammation
Used for research of cancer
Used for research of autoimmune diseases
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IL-17 modulator 3 is a small-molecule IL-17 pathway modulator intended for research use in studies of inflammation, cancer, and autoimmune diseases. It is provided as a chemically characterized research reagent with documentation of purity and structural identifiers suitable for in vitro and preclinical investigations.
High purity (99.5%).
Solid powder with light yellow to yellow appearance.
Molecular formula C31H45N7O4 and molecular weight 579.73.
Structural identifiers available (SMILES and PubChem CID documented).
Supplied in a 10 mg quantity for laboratory research use.
Intended for use in inflammation, cancer, and autoimmune disease research applications.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AMPA receptor modulator-1 can be activated by glutamate thereby modulating ion channels. purity: 98%
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GLP-1R modulator C5 is an allosteric modulator that enhances GLP-1 binding to GLP-1R through a transmembrane site, with an EC50 of 1.59 ± 0.53 μM. It is intended for research use only.
Allosteric modulator
Enhances GLP-1 binding to GLP-1R
Intended for research use only
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A selective small-molecule research ligand for the 5-HT1A serotonin receptor that also exhibits activity at adrenergic α1 and dopamine D2 receptors. Supplied as a white to off-white solid with supporting analytical documentation (COA and datasheet) for preclinical pharmacology and receptor profiling studies.
High affinity for 5-HT1A receptor, IC50 ≈ 2 nM.
Measured off-target activity at adrenergic α1 and dopamine D2 receptors (IC50 ≈ 10 nM and 40 nM).
Supplied as a stable solid suitable for frozen or refrigerated storage.
Certificate of analysis and purity data available to support assay reproducibility.
Useful as a pharmacological tool for serotonin receptor profiling and CNS research.
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DL-Sulforaphane N-acetyl-L-cysteine is a sulforaphane metabolite used in research as an orally active histone deacetylase (HDAC) inhibitor. It is reported to have an extended half-life and improved blood-brain barrier permeability versus the parent compound, and has been used to study autophagy, HDAC activity, and anticancer mechanisms. Supplied as a high-purity solid for laboratory research.
Orally active HDAC inhibitor and sulforaphane metabolite.
Longer half-life and improved blood-brain barrier permeability compared with parent compound.
Reported to induce autophagy, cell-cycle arrest, and apoptosis in certain cancer cell lines.
High-purity solid suitable for research applications.
Soluble in DMSO; store powder frozen for long-term stability.
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GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R through a transmembrane site, with an EC50 of 11.01 ± 2.73 μM.
Allosteric modulator
Enhances GLP-1 binding to GLP-1R via a transmembrane site
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