Phenylpropanoids and polyketides
Medchemexpress LLC (-)-Epicatechin gallate | 1257-08-5 | MFCD00075936 | 99.6% | 442.37 | C22H18O10 | 10 MG
(-)-Epicatechin gallate is a flavonoid gallate used as a research reagent for biochemical and cell-based studies. It inhibits cyclooxygenase-1 (COX-1) with a reported IC50 of approximately 7.5 μM and has reported activity against glucose transporters (GLUT1, GLUT5). The compound is provided as a high-purity analytical reagent suitable for assay development and mechanistic studies.
- Natural flavonoid derivative
- Inhibits COX-1 (IC50 ≈ 7.5 μM)
- Reported GLUT1 and GLUT5 inhibitor
- Molecular formula C22H18O10, molecular weight 442.37
- High purity (HPLC) - 99.6%
- Supplied in small research pack sizes for analytical use
Medchemexpress LLC Apigenin (4',5,7-Trihydroxyflavone) | 520-36-5 | 270.24 | 5 G
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. This natural flavonoid possesses broad biological properties including antioxidative, anti-inflammatory, anticancer, and neuroprotective effects.
- Competitive CYP2C9 inhibitor
- Exhibits antioxidative effects
- Exhibits anti-inflammatory effects
- Exhibits anticancer effects
- Exhibits neuroprotective effects
- Inhibits cell proliferation
- Alleviates Adriamycin (ADR)-induced myocardial injury
Medchemexpress LLC Luteolin-3',7-diglucoside | 52187-80-1 | 5 MG
Luteolin-3′,7-diglucoside is a glycoside that can be isolated from *R. luteolin*. It significantly inhibits cataracts induced in ovine lenses and also inhibits the activity of *Ureaplasma urealyticum* ATCC and clinical strains.
- Glycoside isolated from *R. luteolin*.
- Significantly inhibits cataracts induced in ovine lenses.
- Inhibits activity of *Ureaplasma urealyticum* ATCC and clinical strains.
- High purity of 97.0%.
- Appears as a solid, light yellow to yellow.
Medchemexpress LLC (-)-Epicatechin | 490-46-0 | 95.6% | 290.27 | 1 MG
(-)-Epicatechin is the analytical standard of (-)-Epicatechin, intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) and the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments in techniques such as HPLC, GC, and MS.
- Suitable for research and analytical applications.
- Inhibits cyclooxygenase-1.
- Blocks nuclear localization of p65 subunit of NF-κB.
- Used in qualitative research experiments.
- Used in quantitative research experiments.
- Used in methodological research experiments.
- Compatible with HPLC, GC, and MS techniques.
Apexbio Technology LLC 7,3＇,4＇-Trihydroxyflavone 2150-11-0 5mg
73p4p-Trihydroxyflavone is a small-molecule inhibitor targeting cyclooxygenase-1 (COX-1) and pathways involved in osteoclastogenesis It is designed to inhibit oxidative radical formation and osteoclast differentiation thereby regulating inflammatory and bone resorption pathways 73p4p-Trihydroxyflavone exerts its biological activity primarily through free radical scavenging and downregulation of osteoclast marker genes In in vitro studies 73p4p-Trihydroxyflavone demonstrates inhibition of reactive oxygen species in rat kidney tissue homogenates and suppresses RANKL-induced osteoclastogenesis in mouse bone marrow-derived macrophages Based on these pharmacological properties 73p4p-Trihydroxyflavone holds research potential in biochemical pharmacological antimicrobial and bone metabolism studies