Phenylpropanoids and polyketides
Medchemexpress LLC Luteolin-7-rutinoside | 20633-84-5 | 5 MG
Luteolin-7-rutinoside possesses both anti-arthritic and antifungal activities, which can lead to a combination therapy for treating fungal arthritis caused by *C. albicans* infection. It is intended for research use only and not for sale to patients.
- Possesses anti-arthritic activity.
- Possesses antifungal activity.
- Reduces proliferation of T cells in a dose-dependent manner.
- Shifts Th1-Th2 balance away from Th1 towards Th2-type responses.
- Inhibits nitric oxide (NO) production from macrophages.
Medchemexpress LLC Apigenin-7-diglucuronide | 74696-01-8 | 1 MG
Apigenin-7-diglucuronide is a flavonoid glycoside found in various medicinal plants. It exhibits anti-inflammatory and antioxidant activities, and has been shown to protect retinas against bright light-induced photoreceptor degeneration by inhibiting retinal oxidative stress and inflammation.
- Flavonoid glycoside
- Found in various medicinal plants
- Exhibits anti-inflammatory and antioxidant activities
- Protects retinas against bright light-induced photoreceptor degeneration
- Inhibits retinal oxidative stress and inflammation
- Intended for research use only
Cayman Chemical Cel-Based asy ApIgenIn 100uL
Source Recombinant MERS-CoV C-Terminal His-tagged nucleocapsid protein expressed in insect cells Amino acids 1-413 (full length) MW 46.51 kDa
Selleck Chemical LLC (-)Epicatechin S4723-1mg-5
( )Epicatechin (L-Epicatechin (-)-Epicatechol) is a flavonoid present in cocoa green tea and red wine It is a strong antioxidant has insulin mimic action and improves heart health
TARGETMOL CHEMICALS INC Luteolin 500MG
Also available in 1 g, 1 mL, 10 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant. Purity 97.39%
Medchemexpress LLC Apigenin (4',5,7-Trihydroxyflavone) | 520-36-5 | 270.24 | 5 G
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. This natural flavonoid possesses broad biological properties including antioxidative, anti-inflammatory, anticancer, and neuroprotective effects.
- Competitive CYP2C9 inhibitor
- Exhibits antioxidative effects
- Exhibits anti-inflammatory effects
- Exhibits anticancer effects
- Exhibits neuroprotective effects
- Inhibits cell proliferation
- Alleviates Adriamycin (ADR)-induced myocardial injury
Medchemexpress LLC Apigenin (Standard) | 520-36-5 | 270.24 | 5 MG
Apigenin (Standard) is the analytical standard of Apigenin, intended for research and analytical applications. It is a competitive CYP2C9 inhibitor with a Ki of 2 μM. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS. Features and benefits include:
- Purity: 98.82%
- Appearance: solid
- Color: yellow to brown
- Structure classification: flavonoids, phenols
- Initial source: plants Compositae Baccharis sarothroides A.Gray, plants Umbelliferae
- Endogenous metabolite: human gut microbiota metabolites
Medchemexpress LLC Luteolin-3',7-diglucoside | 52187-80-1 | 5 MG
Luteolin-3′,7-diglucoside is a glycoside that can be isolated from *R. luteolin*. It significantly inhibits cataracts induced in ovine lenses and also inhibits the activity of *Ureaplasma urealyticum* ATCC and clinical strains.
- Glycoside isolated from *R. luteolin*.
- Significantly inhibits cataracts induced in ovine lenses.
- Inhibits activity of *Ureaplasma urealyticum* ATCC and clinical strains.
- High purity of 97.0%.
- Appears as a solid, light yellow to yellow.
Medchemexpress LLC Luteolin-3-O-beta-D-glucuronide | 53527-42-7 | 98.9% | 462.36 g·mol⁻¹ | C21H18O12 | 10 MG
Luteolin-3-O-beta-D-glucuronide is a flavonoid metabolite of luteolin used as a research reagent and analytical standard in biochemical and pharmacological studies. The compound is supplied as a high-purity solid for use in metabolism, enzymology, and analytical method development.
- High purity (~98.9%) suitable for analytical and biological assays.
- Molecular formula C21H18O12 and molecular weight 462.36 g·mol⁻¹.
- Identified by CAS number 53527-42-7 for unambiguous chemical tracking.
- Available in small milligram quantities for assay development and reference use.
- Reported as a luteolin metabolite present in plant sources such as Rosmarinus officinalis.
Medchemexpress LLC Luteolin monohydrate | 6113-16-2 | MFCD00017309 | 99.1% | 304.25 g/mol | C15H12O7 | 250 MG
Luteolin monohydrate is the monohydrate form of luteolin, a naturally occurring flavonoid used in life-science research. It is reported to act as an Nrf2 pathway modulator and shows anti-inflammatory and anticancer activity in cellular studies. It is supplied as a solid and provided in small research quantities for biochemical assays and mechanistic investigations.
- Monohydrate form of luteolin
- Reported Nrf2 inhibitor and bioactive flavonoid
- High purity (99.13%)
- Available in small research quantities, e.g., 250 mg
- Storage: 4°C, sealed, away from moisture; in solution: -80°C (6 months)
Medchemexpress LLC (-)-epicatechin (standard) | 490-46-0 | 290.27 g/mol | C15H14O6 | 10 MG
(-)-Epicatechin (standard) is an analytical reference material of the flavonoid (-)-epicatechin provided as a 10 mg quantity for research and analytical use. It is intended for assay calibration, method development, and reference measurements; not for human or clinical use. Recommended storage is 4°C sealed and protected from light and moisture; in solvent, store at -80°C for up to 6 months or -20°C for up to 1 month.
- Analytical reference standard of (-)-epicatechin.
- Intended for research and analytical applications; not for human use.
- CAS number 490-46-0; molecular formula C15H14O6.
- Supplied as a 10 mg quantity suitable for calibration and method development.
- Recommended storage: 4°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Apigenin | 520-36-5 | 1 ML
Apigenin, also known as 4',5,7-Trihydroxyflavone, functions as a competitive inhibitor of CYP2C9 with a Ki of 2 μM. This compound has been observed to inhibit cell proliferation and suppress clone formation in various cell lines, making it suitable for research applications exploring its biological activity.
- Competitive CYP2C9 inhibitor
- Inhibits cell proliferation
- Suppresses clone formation of cells
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 1 ML
Luteolin 7-O-glucuronide is an inhibitor of Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, and 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It is intended for research use only.
- Inhibits NO production and mRNA expression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
- Inhibits NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages.
- Improves depression-like and stress coping behaviors in mouse sleep deprivation models.
- Reduces increased immobility time and plasma corticosterone levels.
- Reduces TNF-α and IL-1β levels and increases BDNF mRNA expression in the hippocampus of sleep-deprived mice.
Cayman Chemical ApIgenIn 7-glucosIde 10mg
A flavonoid with anti-inflammatory and anxiolytic activities; inhibits LPS-induced nitric oxide production in RAW 264.7 cells from 0.16-10 μM; reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury at 10 mg/kg; increases the number of entries and the time spent in the open arms of the elevated plus maze in rats
