Phenylpropanoids and polyketides
LIFE CHEMICALS USA INC (2S)-2-AMINO-2-(1-HYDROXYC 10G
(2S)-2-AMINO-2-(1-HYDROXYCYCLOPROPYL)ACETIC ACID | Mol Wt: 131.130 | 77448-58-9 | MFCD19212937 | 10 g
Medchemexpress LLC Trans-Cinnamic acid | 140-10-3 | MFCD00004369 | 148.16 | 100 MG
trans-Cinnamic acid is a natural antimicrobial, with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1. This compound is used in various biological applications.
- Antimicrobial activity against various fish pathogens
- Shows moderate inhibition on rainbow trout intestinal isolates and gill isolate
- More effective on bacteria when the pH of the culture media is not neutralized
Medchemexpress LLC 3,4,5-Trimethoxycinnamic acid | 90-50-6 | 99.9% | 238.24 | 25 G
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of *Polygala tenuifolia WILLD*. It has an anti-stress effect and can prolong sleeping time in animals. This compound increases the expression of GAD65 and the γ-subunit of the GABAA receptor, but it does not affect the amounts of α- and β-subunits.
- Anti-stress effect
- Prolongs sleeping time in animals
- Increases expression of GAD65 and γ-subunit of GABAA receptor
- Exhibits sedative effect in rats
- Significantly decreases locomotor activity in mice
- Available in solid form, white to off-white color
Chem-Impex International, Inc. trans-4-Bromocinnamic acid | MFCD00004394 | 5G
trans-4-Bromocinnamic acid, MFCD00004394, 5G
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 25 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, utilized in the development of medicines, cosmetics, and fruit preservation products. It boasts a purity of 99.19% and a molecular weight of 192.21, presenting as a light yellow to light brown solid. This compound also exhibits anti-platelet activity.
- Non-competitive, reversible tyrosinase inhibitor
- IC50 of 4.89 μg/mL and Ki of 1.83 μg/mL against tyrosinase
- Quenches intrinsic fluorescence of the enzyme
- Alters L-tyrosine binding affinity through conformational changes in tyrosinase
- Does not bind to the enzyme's copper ion
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC trans-Cinnamic acid | 140-10-3 | 148.16 | 1 G
Trans-Cinnamic acid is a natural antimicrobial with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1. It shows moderate inhibition on rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1, and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY-VC10, and Y. ruckeri E42. This acid is more effective on bacteria when the pH of the culture media is not neutralized. It also inhibits M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage with an IC50 > 100 μM.
- Natural antimicrobial
- Effective against various fish pathogens and nonpathogenic isolates
- More effective on bacteria in non-neutralized pH culture media
- Inhibits osteoclast differentiation
Medchemexpress LLC trans-Cinnamic acid-d7 | 343338-31-8 | 155.20 | 50 MG
trans-Cinnamic acid-d7 (also known as trans-3-Phenylacrylic acid-d7) is the deuterium-labeled form of trans-Cinnamic acid, a natural antimicrobial. This compound is used in laboratory research and can serve as a tracer or internal standard for quantitative analysis using methods such as NMR, GC-MS, or LC-MS. Deuterium substitution in drug molecules is known for its potential to influence pharmacokinetic and metabolic profiles.
- Deuterium-labeled form of trans-Cinnamic acid.
- Acts as a natural antimicrobial.
- Can be used as a tracer or internal standard.
- Useful for quantitative analysis via NMR, GC-MS, or LC-MS.
- Deuterium substitution may impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC p-Coumaric acid | 501-98-4 | 164.16 | 1 ML
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity.
- Inhibits cell proliferation and promotes apoptosis.
- Exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Can significantly inhibit the proliferation of human and mouse melanoma cells.
- Shows antibacterial activity against gram-negative and gram-positive bacteria, with MIC values for Escherichia coli, Streptococcus dysenteriae, and Salmonella typhimurium of 80, 10, and 20 μg/ml respectively.
- Has a protective effect on colon pretumor induced by 1,2 dimethylhydrazine (DMH) in rats.
- Alleviates nephrotoxicity induced by Doxorubicin by inhibiting oxidative stress, inflammation, and apoptosis.
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.8% | C10H10O2 | 50 G
3-Methylcinnamic acid is a drug intermediate used for the synthesis of various active compounds. This product is for research use only and is not sold to patients.
- Used for the synthesis of various active compounds.
- Appears as a white to off-white solid.
- Intended for research use only.
- Purity of 99.77%.
- Storage as powder at -20°C for 3 years or 4°C for 2 years.
- Storage in solvent at -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | MFCD02605317 | 99.82% | C14H11FO2 | 50 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate used for the synthesis of various active compounds. This product is provided as a solid and is intended for research use only.
- Drug intermediate for synthesis of active compounds
- Provided as a solid
- For research use only
Accela Chembio Inc 4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 100g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 100g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
Medchemexpress LLC p-Hydroxycinnamic acid | 7400-08-0 | 1 ML
p-Hydroxycinnamic acid, also known as p-Coumaric acid, is a common dietary phenol and ubiquitous plant metabolite. It is recognized for its antioxidant and anti-inflammatory properties. This compound can inhibit platelet activity and modulates platelet function, particularly under shear-inducing conditions.
- Inhibits platelet activity
- Exhibits antioxidant properties
- Provides anti-inflammatory benefits
- Modulates platelet function under shear-inducing conditions
- Interferes with the arachidonic acid cascade
- Demonstrates IC50s of 371 μM for thromboxane B2 production
- Shows IC50s of 126 μM for lipopolysaccharide-induced prostaglandin E2 generation
eMolecules 4'-(4-Fluorobenzyloxy)acetophenone | 72293-96-0 | MFCD00173651 | 25g
Oakwood Chemical | 4'-(4-Fluorobenzyloxy)acetophenone | 25g | 537669236 | 008324 | | 72293-96-0 | MFCD00173651 | 244.265 | C15H13FO2
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Medchemexpress LLC m-Coumaric acid | 588-30-7 | >99.8% | 164.16 | 500 MG
m-Coumaric acid | 588-30-7 | >99.8% | 164.16 | 500 MG