Other Solvents
Medchemexpress LLC Losartan-d4 | 1030937-27-9 | 99.4% | 426.94 | 5 MG
Losartan-d4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Picolinic-3,4,5,6-d4 acid | 284487-61-2 | MFCD00145121 | 100.0% | 127.14 | C6HD4NO2 | 10 MG
Picolinic acid-d4 is the deuterium-labeled isotopologue of picolinic acid used as a stable-isotope reference standard and tracer in analytical workflows. It is supplied with high isotopic enrichment for use as an internal standard in quantitative methods and is intended for research use only.
- Deuterium-labeled internal standard for quantitative analysis.
- High isotopic enrichment (99.99%) for accurate tracing.
- Suitable for NMR, GC-MS, and LC-MS applications.
- Available in small laboratory-scale quantities for standards preparation.
- Provided with product quality data for analytical use.
Cambridge Isotope Laboratories L-LYSINE:2HCL (ALPHA-15N, 95-99%), 0.25 G, 204451-50-3
L-LYSINE:2HCL (ALPHA-15N, 95-99%), 0.25 G, 204451-50-3
Medchemexpress LLC Methomyl-d3 | 1398109-07-3 | C5H7D3N2O2S | 1 MG
Methomyl-d3 is a deuterium labeled compound primarily used as a tracer and as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes such as hydrogen, carbon, and other elements into drug molecules, particularly deuterium, is used for quantitation during drug development and has shown potential in influencing the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Fenofibric acid-d6 | 1092484-69-9 | 99.6% | 5 MG
Fenofibric acid-d6 (FNF acid-d6) is the deuterium-labeled form of Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, acts as a PPAR activator with EC50s of 22.4 μM for PPARα, 1.47 μM for PPARγ, and 1.06 μM for PPARδ. It also inhibits COX-2 enzyme activity with an IC50 of 48 nM. Deuterium substitution in drug molecules is of interest due to its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
Medchemexpress LLC Cholic acid-d5 | 53007-09-3 | MFCD08702879 | 98.0% | 413.60 | C24H35D5O5 | 10 MG
Cholic acid-d5 is the deuterium-labeled analogue of cholic acid supplied for use as an internal standard or tracer in analytical workflows. It supports quantitative method development and routine analyses in NMR, GC-MS, and LC-MS, and is intended for research use only.
- Deuterium-labeled internal standard for quantitative NMR, GC-MS, and LC-MS.
- High purity (98.0%).
- Molecular formula C24H35D5O5; molecular weight 413.60.
- CAS number 53007-09-3.
- Provided as a 10 mg vial; store protected from light and under inert atmosphere.
- For research use only; not for human or animal therapeutic use.
Medchemexpress LLC Simvastatin-d6 | 1002347-71-8 | 99.6% | 424.60 | 1 ML
Simvastatin-d6 is a deuterium-labeled form of Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase with a Kᵢ of 0.2 nM. The incorporation of stable heavy isotopes into drug molecules makes it useful as a tracer for quantitative analysis during drug development. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes for quantitation during drug development.
- Deuteration may impact pharmacokinetic and metabolic profiles of drugs.
- Functions as a competitive inhibitor of HMG-CoA reductase.
- Exhibits a high affinity with a Kᵢ of 0.2 nM for HMG-CoA reductase.
Cambridge Isotope Laboratories Simazine (unlabeled) 100 ug/mL in methanol 1 2 mL
Simazine (unlabeled) 100 ug/mL in methanol 1 2 mL
Cayman Chemical DeferIpron-d3 1mg
An internal standard for the quantification of deferiprone by GC- or LC-MS
Medchemexpress LLC 2-aminohexane-d6 | 1219802-28-4 | 97.9% | 107.23 g/mol | C6H9D6N | 5mg
2-Aminohexane-d6 is the deuterium labeled 2-Aminohexane[1]
Cambridge Isotope Laboratories CREDENTIALED E. COLI CELL EXTRACT KIT (DRIED DOWN), 1 KIT
CREDENTIALED E. COLI CELL EXTRACT KIT (DRIED DOWN), 1 KIT
Medchemexpress LLC Corticosterone-d8 | 1271728-07-4 | 99.91% | 5 MG
Corticosterone-d8 is the deuterium-labeled Corticosterone. Corticosterone is an adrenocortical steroid that exhibits modest but significant activities as both a mineralocorticoid and a glucocorticoid. The incorporation of stable heavy isotopes like deuterium into drug molecules is primarily for quantitation during drug development, with deuteration specifically recognized for its potential impact on the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7 | 1392208-04-6 | 99.6% | 1 MG
(Rac)-Ropivacaine-d7 is a stable isotope-labeled compound, identified as 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7. It appears as a white to off-white solid with an isotopic enrichment of 99.11%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- High purity of 99.6% (HPLC)
- Stable under recommended storage conditions
- Ideal for laboratory chemical applications and substance manufacturing
- For research use only
Medchemexpress LLC 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy-2,4,6-d3)methyl]- | 1192812-66-0 | 98.0% | 5 MG
Metaxalone-d3 is a deuterium-labeled derivative of Metaxalone, an FDA-approved muscle relaxant. It primarily acts on the central nervous system by inhibiting polysynaptic reflex arcs. It also inhibits MAO-A, offering anti-inflammatory and antioxidant effects. Stable heavy isotopes have been incorporated into drug molecules for tracing and can influence drug pharmacokinetics and metabolic profiles.
- Deuterium labeled Metaxalone
- FDA-approved muscle relaxant
- Inhibits polysynaptic reflex arcs
- Inhibits MAO-A, providing anti-inflammatory and antioxidant effects
- Isotopic enrichment of 99.10%
Medchemexpress LLC Sotalol-d6 hydrochloride | 1246820-85-8 | 99.0% | 5 MG
Sotalol-d6 hydrochloride is a deuterium labeled Sotalol hydrochloride. It is an orally active, non-selective competitive β-adrenergic receptor blocker and a potent antiarrhythmic agent. It blocks β-receptors and potassium KCNH2 channels.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS